DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kz and AT4G18465

DIOPT Version :9

Sequence 1:	NP_001284815.1	Gene:	kz / 31205	FlyBaseID:	FBgn0001330	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_567558.2	Gene:	AT4G18465 / 827579	AraportID:	AT4G18465	Length:	695	Species:	Arabidopsis thaliana

Alignment Length:	807	Identity:	246/807 - (30%)
Similarity:	377/807 - (46%)	Gaps:	184/807 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 VQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQ-HKMIGVTEPRRV 316
            ::..|.|||:.....:::..:..:...|:.||||||||||:||:|.|||:|: .::|..|:|||:
plant    41 IEKQRQRLPVYKYRTEILYLVENHATTIIVGETGSGKTTQIPQYLKEAGWAEGGRVIACTQPRRL 105

  Fly   317 AAIAMSKRVAHEM--NLPESEVSYLIRFEGNVTP-ATRIKFMTDGVLLKEIETDFLLSKYSVIIL 378
            |..|:|.|||.||  ||.| ||.|.||||.:.|. .|.:||:|||||::|:..|.||:|||||::
plant   106 AVQAVSARVAEEMGVNLGE-EVGYTIRFEDHTTSGVTSVKFLTDGVLIREMMEDPLLTKYSVIMI 169

  Fly   379 DEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLR---VSDFTENTRLF---------- 430
            |||||||:.||||:|||.:|    .:|...|:|||.|||:.   :|:|..:::..
plant   170 DEAHERSISTDILLGLLKKI----QRRRPELRLIISSATIEAKTMSNFFNSSKKRHAPEGSTPGP 230

  Fly   431 KIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKL 495
            |:.|.:|.||.|.|.|.||:.:....||:.......|.|:.:.|.|.:|:|:|||:::...:
plant   231 KLEPAILSVEGRGFSVKIHYVEEPVSDYIRSVVSTILLINEREPPGDVLVFLTGQEDIETAI--- 292

  Fly   496 RRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMA 560
                              |:.|||..                             |.:|
plant   293 ------------------KLLEEEAH-----------------------------SNQK------ 304

  Fly   561 LPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSL 625
                                                        :.||        |..|||||.
plant   305 --------------------------------------------NSSG--------LLPLPLYSG 317

  Fly   626 LSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTS 690
            ||..:|..||.|.|.|.|..::|||:||||||:..:.||:|.|..|.:.|:.::.:.:.||...|
plant   318 LSRSEQELIFTPTPRGKRKVILSTNIAETSLTLEGVVYVIDSGFSKQKFYNPISDIESLVVAPIS 382

  Fly   691 KASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPF 755
            ||||.||:|||||:..|.|||||:...:.:.......|::|:..:...::|::.:|||.::.|.:
plant   383 KASARQRSGRAGRVRPGKCYRLYTEDYFLNQMPGEGIPEMQRSNLVSTVIQLKALGIDNILGFDW 447

  Fly   756 PSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLL 820
            |:||..   :|..|.|.||.:|::...:.....|.    |..::..|:.|...||:..|.:....
plant   448 PAPPSS---EAMIRALEVLYSLQILDDDAKLTSPT----GFQVAELPLDPMISKMILASSELGCS 505

  Fly   821 PYTVCLVAALSVQEV-LIETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAE 884
            ...:.:.|.||||.| :|..|||:::|.|         :..:||:.     ||.:..|..
plant   506 HEIITIAAVLSVQSVWIIARGVQKEQDEA---------KLRFAAAE-----GDHVTFLNV----- 551

  Fly   885 YAG-SQGRLP-EFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDPELKPPTDAQARFLR 947
            |.| .:.:.| ::|..|.|..::|.:|.::|.||.....      .||:  .|| ..|.....:|
plant   552 YKGFLESKKPTQWCYKNFLNYQSMKKVVEIRDQLKRIAR------RLGI--TLK-SCDGDMEAVR 607

  Fly   948 QILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYE 1012
            :.:.||......|..|.::           ..|......|..::|.||||.:..|:||:||....
plant   608 KAVTAGFFANACRLEPHSN-----------GVYKTIRGSEEVYIHPSSVLFRVNPKWVVYQSIVS 661

  Fly  1013 LQNGDSTKMFIRGITAIEPEWLLLYVP 1039
            .:     :.::|.:..|.|.||....|
plant   662 TE-----RQYMRNVVTINPSWLTEVAP 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	246/807 (30%)
		DEXDc	279..418	CDD:238005	81/142 (57%)
		P-loop_NTPase	369..>500	CDD:304359	53/143 (37%)
		HELICc	619..704	CDD:197757	42/84 (50%)
		HA2	774..859	CDD:214852	21/85 (25%)
		OB_NTP_bind	915..1039	CDD:285018	29/123 (24%)
AT4G18465	NP_567558.2	HrpA	41..683	CDD:224557	245/805 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820