DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kz and AT2G47250

DIOPT Version :9

Sequence 1:	NP_001284815.1	Gene:	kz / 31205	FlyBaseID:	FBgn0001330	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_182247.1	Gene:	AT2G47250 / 819338	AraportID:	AT2G47250	Length:	729	Species:	Arabidopsis thaliana

Alignment Length:	814	Identity:	255/814 - (31%)
Similarity:	372/814 - (45%)	Gaps:	204/814 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 RTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHK------M 307
            |..|:...|..||:..::...:.|:|.|..:|:.||||||||||:|||:.:|..|.:.      :
plant    54 RYFEILEKRRDLPVWLQKDDFLNTLNSNQTLILVGETGSGKTTQIPQFVLDAVVADNSDKGRKWL 118

  Fly   308 IGVTEPRRVAAIAMSKRVAHEMNLP-ESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLS 371
            :|.|:||||||:::|:|||.||::. ..||.|.||||...:..|.:|::|||:||:|...|.||.
plant   119 VGCTQPRRVAAMSVSRRVADEMDVSIGEEVGYSIRFEDCTSSRTMLKYLTDGMLLREAMADPLLE 183

  Fly   372 KYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQP-LKLIIMSATLRVSDFTENTRLFKIPPP 435
            :|.||||||||||::.||:|.|||..::     |.:| |||::|||||....|.|    :....|
plant   184 RYKVIILDEAHERTLATDVLFGLLKEVL-----RNRPDLKLVVMSATLEAEKFQE----YFSGAP 239

  Fly   436 LLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFP 500
            |:||..|..||.|.:.:....||:..|.|..::||...|.|.||:|:||::|:....||:
plant   240 LMKVPGRLHPVEIFYTQEPERDYLEAAIRTVVQIHMCEPPGDILVFLTGEEEIEDACRKI----- 299

  Fly   501 YHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKIN 565
                 .|:|:..|
plant   300 -----NKEVSNLG---------------------------------------------------- 307

  Fly   566 LDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEK 630
                                             |::|             |:.|:||||.|....
plant   308 ---------------------------------DQVG-------------PVKVVPLYSTLPPAM 326

  Fly   631 QNRIFLPVP-------DGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTY 688
            |.:||.|.|       ...|..|||||:|||||||..|.||:|.|..|.::|:....|.:.:|:.
plant   327 QQKIFDPAPVPLTEGGPAGRKIVVSTNIAETSLTIDGIVYVIDPGFAKQKVYNPRIRVESLLVSP 391

  Fly   689 TSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHF 753
            .|||||.||:|||||...|.|:|||:...:|:..:..:.|:|.:..:.:.:|.::.:|||.:|||
plant   392 ISKASAHQRSGRAGRTRPGKCFRLYTEKSFNNDLQPQTYPEILRSNLANTVLTLKKLGIDDLVHF 456

  Fly   754 PFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQN 818
            .|..||....|..|...|..||||        |....:|:.|.::|.||:.|:..|||.:|.:.|
plant   457 DFMDPPAPETLMRALEVLNYLGAL--------DDEGNLTKTGEIMSEFPLDPQMSKMLIVSPEFN 513

  Fly   819 LLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQ-----LLGDPMVLLR 878
            .....:.:.|.|||                  .|.|.|.|::..|:...:     :.||.:.||.
plant   514 CSNEILSVSAMLSV------------------PNCFVRPREAQKAADEAKARFGHIDGDHLTLLN 560

  Fly   879 AVGAAEYAGSQGRLPEFCAANGLRQKAM---SEVRKLRVQLTNEINLNVSDVELGVDPELKPPTD 940
            ...|.:.....   |.:|..|.:..:||   ..||:..|::.:..||.:..            ||
plant   561 VYHAYKQNNED---PNWCFENFVNNRAMKSADNVRQQLVRIMSRFNLKMCS------------TD 610

  Fly   941 AQAR----FLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKA 1001
            ..:|    .:|:.:|||...:||            ...|..:.....| .:...||.|:.|..|
plant   611 FNSRDYYVNIRKAMLAGYFMQVA------------HLERTGHYLTVKD-NQVVHLHPSNCLDHK- 661

  Fly  1002 PEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLL 1035
            ||||||.| |.|    :|:.|||.:|.|..|||:
plant   662 PEWVIYNE-YVL----TTRNFIRTVTDIRGEWLV 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	255/814 (31%)
		DEXDc	279..418	CDD:238005	73/146 (50%)
		P-loop_NTPase	369..>500	CDD:304359	55/131 (42%)
		HELICc	619..704	CDD:197757	44/91 (48%)
		HA2	774..859	CDD:214852	23/84 (27%)
		OB_NTP_bind	915..1039	CDD:285018	36/125 (29%)
AT2G47250	NP_182247.1	HrpA	40..711	CDD:224557	255/814 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820