Protein Alignment kz and dhx37

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_002944206.3
• Gene: dhx37 / 734015
• XenbaseID: XB-GENE-986494
• Length: 1147
• Species: Xenopus tropicalis
• Alignment Length: 1237
• Identity: 560/1237 - (45%)
• Similarity: 772/1237 - (62%)
• Gaps: 144/1237 - (11%)

  Fly     1 MGK--KVHNAKARQNPQTIVDNSA--VKKIQIDVDAVAGGNQV-GYDEANALVLPSEKRATKIKV 60
            |||  |.||.||||..::..:.::  .:.:|::::   |..|: |.||:||||||.:|...|...
 Frog     1 MGKMRKRHNWKARQQVKSTEEEASGDQEHLQLELE---GSEQLKGVDESNALVLPGKKSKRKKIN 62

  Fly    61 DKVQHVKILSKKQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQ-QYTSISQVQTVGLKRL 124
            :.....|.||:||:|.||.::::|:||..||:||..|...|..|:||. .||:         .:|
 Frog    63 ESGPTKKPLSRKQKKVLQKVLEQKEKKSKRAELLSKLVESQASEKELNLLYTT---------SKL 118

  Fly   125 PTLDEYLAKKKERQAQVLAEKSSASGLRVNAIKGSKRKLLVEEEEELQAKRKNPNVISVEEDDED 189
            .|.|...:.|:     .:.|..|:...|:::|.|:.:|...|||:            ..||.|..
 Frog   119 GTGDRLFSAKR-----AIEEADSSLQGRISSIGGANKKRKSEEED------------VAEESDTT 166

  Fly   190 SSSSDEDDE------------------EAPAQS-APIAIPTPVSIAPPQIAVKPPIKKLKPEPNP 235
            |.||.||::                  ..|..| .|.|.|||   .||...  ||.|..:...:.
 Frog   167 SESSGEDEDPTEREQEKDGENDHTASCSVPCTSERPHAKPTP---KPPNDT--PPKKPSEIPSSQ 226

  Fly   236 PACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEA 300
            ||     :::||.|:.::|.|||:||||||||.:||.|.|||:|::.||||||||||:|||||||
 Frog   227 PA-----IFIPVDRSPDIQEARLKLPILAEEQVIMEAIKENPVVVLCGETGSGKTTQVPQFLYEA 286

  Fly   301 GY-AQHKMIGVTEPRRVAAIAMSKRVAHEMNLPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEI 364
            || :::.:||:||||||||||||:|||.|||||:|.:||.||:||||:..|:.||||||||||||
 Frog   287 GYGSENDVIGITEPRRVAAIAMSQRVALEMNLPQSVISYQIRYEGNVSNETKTKFMTDGVLLKEI 351

  Fly   365 ETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRL 429
            :.||||::|.|:|:|||||||||||||:||||||||||.|:|.||||||||||||:.|||||.||
 Frog   352 QKDFLLTRYRVVIIDEAHERSVYTDILIGLLSRIVPLRAKKGSPLKLIIMSATLRIEDFTENKRL 416

  Fly   430 FKIPPPLLKVEARQFPVTIHFQKRTP-DDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVR 493
            |.:|||::||:|||||||:||.|||| :||..|.|||..|||..||.||||||:|||.||:.|.|
 Frog   417 FPVPPPVIKVDARQFPVTVHFNKRTPLEDYAGECYRKVCKIHRMLPAGGILIFLTGQAEVHSLCR 481

  Fly   494 KLRRTFP-----YHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKK 553
            :||:|||     ||:|           :|:|                    |.:..:|..:||:.
 Frog   482 RLRKTFPFCGRNYHNA-----------TEDE--------------------DSQEAVRRFKKSRP 515

  Fly   554 KFLAQMALPKINLDDYKL-PGDDTEADMHEQPDEDDEQEGLEEDNDDELG----LEDESGMGSGQ 613
            |  ..|.||||:|..|.. |.|:.:.|   :...|||::|...|.|.:||    .|||....|
 Frog   516 K--KTMNLPKIDLASYSAQPLDEGDED---REAADDEEDGSGSDLDIDLGDEGAEEDEKADSS-- 573

  Fly   614 RQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKL 678
             .||:||||||||:.|||.::|.|.|.|.|||||:|||||||||||.||||||||:.|.|.|||:
 Frog   574 -LPLFVLPLYSLLAPEKQAKVFRPPPPGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDKV 637

  Fly   679 TGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMR 743
            ||||:|.|.:||:|||:||||||||...|||||||||||:.| ||.||.|:|.::|||||:|||:
 Frog   638 TGVSSFRVDWTSQASANQRAGRAGRTEPGHCYRLYSSAVFAD-FEQFSPPEITRRPVEDLVLQMK 701

  Fly   744 CMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGAL-EVAKT------ENTDLPPAVTRLGHVISRF 801
            .:.|::||:||||:||....|.|||..||.|||| |..||      :...|...:|.||..::.|
 Frog   702 DLNIEKVVNFPFPTPPSADALIAAEELLISLGALQEPPKTGRLNDLQKAKLSSPITPLGKTMASF 766

  Fly   802 PVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQR------DEDVAPGAN-RFHRKRQ 859
            |||||:.|||||..|...|||.:.:|||::|:|:..|  |.|      ::::..|.. |..:.::
 Frog   767 PVAPRYAKMLALGRQHECLPYVITIVAAMTVRELFEE--VDRPAVSDEEKELLKGKKARVLQMQR 829

  Fly   860 SWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNV 924
            .||..|:.|.|||.||:|.||||.||:|.:   |:||..||||.|||.|:|:||.|||..:|...
 Frog   830 IWAGQGSAQKLGDLMVMLGAVGACEYSGLE---PKFCERNGLRFKAMLEIRRLRGQLTTTVNSLC 891

  Fly   925 SDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPA 989
            .|..|.:|.::.|||::|..:||||:::|:||.:||::...::.|::.|.    ||....:|||.
 Frog   892 PDTHLYLDSKMNPPTESQVTYLRQIVMSGLGDHIARRIRQEELLDEKWRN----AYKTPLLEEPV 952

  Fly   990 FLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLCNIREVREDPAPR 1054
            |:|.:|.|.::.|::|:|||..|     :|||:::|::|||.||:.:.:|..|:.....|||.|.
 Frog   953 FIHPNSALFRQLPDFVVYQEIME-----TTKMYMKGVSAIEAEWIPILLPQYCHFGNPLEDPPPF 1012

  Fly  1055 FDKTSGKIFCHVDATFGKSGWELPLGEVEMPLSEKACCYFGMFLLDGEVCSRLADFRSKLKSTPA 1119
            :...:|::.||..:||.:.||:||....:.|...:...||.||||:|:|..:|..:||.|.|||.
 Frog  1013 YCSETGRVKCHRPSTFYRVGWQLPAVVADYPEGLERYKYFAMFLLEGKVVEKLGSYRSVLLSTPI 1077

  Fly  1120 SVIKSWSSMNNKVLRFKRALITKQIHNRQALIDQWNSDPHFLLEEYQNLLYDVALSELTPLWPPV 1184
            :::|:|:.:..:.....:||:::....:.||:..|..:|.:||..:.....:....::...|||:
 Frog  1078 TMLKTWAKLQPRTEILLKALVSENADCQSALLAAWKKNPKYLLSAFCQWTPEAIHEDIAKAWPPI 1142

  Fly  1185 DK 1186
            .:
 Frog  1143 QQ 1144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	438/836 (52%)
		DEXHc_DHX37	260..439	CDD:350740	133/179 (74%)
dhx37	XP_002944206.3	PTZ00108	<59..222	CDD:240271	56/193 (29%)
		HrpA	246..>997	CDD:441249	428/804 (53%)