Protein Alignment kz and Dhx34

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_082159.3
• Gene: Dhx34 / 71723
• MGIID: 1918973
• Length: 1145
• Species: Mus musculus
• Alignment Length: 822
• Identity: 226/822 - (27%)
• Similarity: 360/822 - (43%)
• Gaps: 210/822 - (25%)

  Fly   190 SSSSDEDDEEAPAQSAPIAIPTPVSIAPP---QIAVKPPIKKLKPEPN---PPACIHQTVYVPVH 248
            :|...|.|...|..........|::..|.   .:::..|..:.:..|.   ||..:.:.....:|
Mouse    77 TSQKKEKDPGMPKHGIAALADLPLTYDPRYRINLSILSPDTRGRHGPGRGLPPERVSEFRRALLH 141

  Fly   249 -----------RTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGY 302
                       |..::|..|..|||.....::::|:.|:.:|:|||:||.||:||:||:|..||:
Mouse   142 YLDFQQKQAFGRLVKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGF 206

  Fly   303 AQHKMIGVTEPRRVAAIAMSKRVAHE-MNLPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIET 366
            :.   :..|:|||:|.|:::|||..| ::...|:|.|.||||...:.||:|.|:|.|:||::|:.
Mouse   207 SH---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQR 268

  Fly   367 DFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFK 431
            :..|.:|.|:|:||.|||.::.|.|:|:|.|::|.|    ..||:|:||||:.:|.|:.    :.
Mouse   269 EPSLPQYQVLIVDEVHERHLHNDFLLGVLQRLLPQR----PDLKVILMSATINISLFSS----YF 325

  Fly   432 IPPPLLKVEARQFPVTIHFQKRTPDDYVAEA-------YRKTLK-IHNKLP---EGGILIFVTGQ 485
            ...|:::|..|.||:|:.:|.:..|...:::       :.:.|: |.||.|   .|.:|:|::|.
Mouse   326 SHAPVVQVPGRLFPITVVYQPQEADQTASKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVFLSGM 390

  Fly   486 QEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRK 550
            .|:.                                 |:.|||.
Mouse   391 AEIT---------------------------------TVLDAAQ--------------------- 401

  Fly   551 SKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQ 615
                  |..:|.                                                  ||
Mouse   402 ------AYASLT--------------------------------------------------QR- 409

  Fly   616 PLW-VLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYD--- 676
              | ||||:|.||...|:::|...|.|.|.|::|||:||||:||..|::|||.|:.|...||
Mouse   410 --WVVLPLHSALSVSDQDKVFDVAPAGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQA 472

  Fly   677 KLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQ 741
            ||..:..|   :.|:|||:||.|||||...|.|||||:.:.| |.|..:..|:|::..::.|:||
Mouse   473 KLQRLQEF---WISQASAEQRKGRAGRTGPGVCYRLYAESDY-DAFAPYPVPEIRRVALDALVLQ 533

  Fly   742 MRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPR 806
            |:.|.:.....|||..||....::.|...|...|||        |...|:|.:|.::::.||...
Mouse   534 MKSMSVGDPRTFPFIEPPPPASVETAILYLQEQGAL--------DSSEALTPIGSLLAQLPVDVV 590

  Fly   807 FGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLG 871
            .||||.|....:|....:.:.||||||.....: .|.:.|.|.........:            |
Mouse   591 IGKMLILGSMFSLAEPVLTIAAALSVQSPFTRS-AQSNLDCATARRPLESDQ------------G 642

  Fly   872 DPMVLLRAVGAAEYAGSQ--GRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDPE 934
            ||..|.....|.....|:  |...::|...|:.:..:.|:..||.|. .|:   :.|..|....:
Mouse   643 DPFTLFNVFNAWVQVKSERSGNSRKWCRRRGVEEHRLYEMANLRRQF-KEL---LEDHGLLSGAQ 703

  Fly   935 LKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRL 976
            :..|.|:.:|                      :..:.|||.|
Mouse   704 VVAPGDSYSR----------------------LQQRRERRAL 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	212/735 (29%)
		DEXHc_DHX37	260..439	CDD:350740	72/179 (40%)
Dhx34	NP_082159.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		HrpA	162..>628	CDD:441249	187/602 (31%)
		DEAH box	281..284		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	726..764
		OB_NTP_bind	800..911	CDD:400182
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1091..1114