Protein Alignment kz and Dhx34

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001258381.1
• Gene: Dhx34 / 684903
• RGDID: 1584452
• Length: 1143
• Species: Rattus norvegicus
• Alignment Length: 789
• Identity: 220/789 - (27%)
• Similarity: 353/789 - (44%)
• Gaps: 188/789 - (23%)

  Fly   191 SSSDEDDEEAPAQSAPIAIPTPVSIAPP---QIAVKPPIKKLKPEPN---PPACIHQTVYVPVH- 248
            :|..|.|...|..........|.:..|.   .:::..|..:.:..|.   ||..:.:.....:|
  Rat    77 TSQKEKDPGQPKHGIAALADLPCTYDPRYRINLSILGPDTRGRHGPGKGLPPERVSEFRRALLHY 141

  Fly   249 ----------RTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYA 303
                      |..::|..|..|||.....::::|:.|:.:|:|||:||.||:||:||:|..||::
  Rat   142 LDFQQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFS 206

  Fly   304 QHKMIGVTEPRRVAAIAMSKRVAHE-MNLPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETD 367
            .   :..|:|||:|.|:::|||..| ::...|:|.|.||||...:.||:|.|:|.|:||::|:.:
  Rat   207 H---VACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQCE 268

  Fly   368 FLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKI 432
            ..|.:|.|:|:||.|||.::.|.|:|:|.|::|.|    ..||:|:||||:.:|.|:.    :..
  Rat   269 PRLPQYQVLIVDEVHERHLHNDFLLGVLQRLLPQR----PDLKVILMSATINISLFSS----YFS 325

  Fly   433 PPPLLKVEARQFPVTIHFQKRTPDDYVAEA-------YRKTLK-IHNKLP---EGGILIFVTGQQ 486
            ..|:::|..|.||:|:.:|.:..:...:::       :.:.|: |.||.|   .|.:|:|::|..
  Rat   326 HAPVVQVPGRLFPITVVYQPQEAEQSASKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVFLSGMA 390

  Fly   487 EVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKS 551
            |::                                 |:.|||.
  Rat   391 EIS---------------------------------TVLDAAQ---------------------- 400

  Fly   552 KKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQP 616
                 |...|.                                                  ||
  Rat   401 -----AYATLT--------------------------------------------------QR-- 408

  Fly   617 LW-VLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYD---K 677
             | ||||:|.||...|:::|...|.|.|.|::|||:||||:||..|::|||.|:.|...||   |
  Rat   409 -WVVLPLHSALSVADQDKVFDVAPAGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAK 472

  Fly   678 LTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQM 742
            |..:..|   :.|:|||:||.|||||...|.|||||:.:.| |.|..:..|:|::..::.|:|||
  Rat   473 LQRLQEF---WISQASAEQRKGRAGRTGPGVCYRLYAESDY-DAFAPYPVPEIRRVALDALVLQM 533

  Fly   743 RCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRF 807
            :.|.:.....|||..||....::.|...|...|||        |...|:|.:|.::::.||....
  Rat   534 KSMSVGDPRTFPFIEPPPAASVETAILYLQDQGAL--------DSSEALTPIGSLLAQLPVDVVI 590

  Fly   808 GKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGD 872
            |||:.|....:|....:.:.||||||.....: .|.:.|.|.........:            ||
  Rat   591 GKMMILGSMFSLAEPVLTIAAALSVQSPFTRS-AQSNLDCATARRPLESDQ------------GD 642

  Fly   873 PMVLLRAVGAAEYAGSQ--GRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDPEL 935
            |..|.....|.....|:  |...::|...|:.:..:.|:..||.|. .|:   :.|..|....::
  Rat   643 PFTLFNVFNAWVQVKSERSGNSRKWCRRRGVEEHRLYEMANLRRQF-KEL---LEDHGLLRGAQV 703

  Fly   936 KPPTDAQAR 944
            ..|.|:.:|
  Rat   704 VAPRDSYSR 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	206/703 (29%)
		DEXHc_DHX37	260..439	CDD:350740	72/179 (40%)
Dhx34	NP_001258381.1	HrpA	161..>627	CDD:441249	185/602 (31%)
		OB_NTP_bind	798..909	CDD:400182