Protein Alignment kz and DHX32

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_047281423.1
• Gene: DHX32 / 55760
• HGNCID: 16717
• Length: 792
• Species: Homo sapiens
• Alignment Length: 954
• Identity: 194/954 - (20%)
• Similarity: 354/954 - (37%)
• Gaps: 293/954 - (30%)

  Fly   167 EEEELQA------KRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPP 225
            |||.|:.      ||..|..:...:.||:...:.||.|..|....|.:
Human     2 EEEGLECPNSSSEKRYFPESLDSSDGDEEEVLACEDLELNPFDGLPYS----------------- 49

  Fly   226 IKKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKT 290
                                  .|..::...|..|||..|:...||.:.:|.||||:|:...||:
Human    50 ----------------------SRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKS 92

  Fly   291 TQLPQFLYE---AGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNLP-ESEVSYLIRFEGNVTPATR 351
            .|:||:..|   :.:.||..:..|:..:...:.::.|||.||::. ..||.|:|.||...|..|.
Human    93 AQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETI 157

  Fly   352 IKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSA 416
            :::.||.:|.:|:.::..|..|.|||||:.||||:.||:|:|||..::..|.:    |||||.|:
Human   158 LRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPE----LKLIINSS 218

  Fly   417 TLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIF 481
            ...:|..  |:....:  |:::|: .:.||.:.:......|......|...:||:...:|.|::|
Human   219 PHLISKL--NSYYGNV--PVIEVK-NKHPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVF 278

  Fly   482 VTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIR 546
            :..:|::.::.                             ||:
Human   279 LACEQDIEKVC-----------------------------ETV---------------------- 292

  Fly   547 NIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGS 611
                                  |:  |.:...|:.|
Human   293 ----------------------YQ--GSNLNPDLGE----------------------------- 304

  Fly   612 GQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLC-------VVSTNVAETSLTIPHIKYVVDCGR 669
                 |.|:|||    .:::..:|.|:.:..:.|       |::|:..|..:....:::|:|.|.
Human   305 -----LVVVPLY----PKEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGV 360

  Fly   670 QKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQK-K 733
            ::.::|:.....::.|:...|::.|:.|....|..|:|..:.||:        |:|:..|:.. |
Human   361 ERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYT--------EEFASKDMTPLK 417

  Fly   734 PVE-------DLMLQMRCMGIDRVVHFPFPSPPDQVQL--------------------------- 764
            |.|       .::|.|:.:.|..:.|..|.:.|..:.|
Human   418 PAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPGSLMLPCQPGIRLRFTFSCPFSVLSSHDAQQC 482

  Fly   765 ----------------QAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLAL 813
                            :|.|..:..|..|:.....:.|  ..::..|.::|.||:.|:..|.:..
Human   483 TQAWRGRWFGLKHFPARAPESLMQALEDLDYLAALDND--GNLSEFGIIMSEFPLDPQLSKSILA 545

  Fly   814 SHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANR---------FHRKRQSWAASGNYQL 869
            |.:.:.:...:.:.|.::.....        ..|..||..         .|.:...:.....|:.
Human   546 SCEFDCVDEVLTIAAMVTAPNCF--------SHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKA 602

  Fly   870 LGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDPE 934
            ..|..:    ..::||...:.....|...:.||   |::|  :|.:|. ||   :..:||   |.
Human   603 YQDTTL----NSSSEYCVEKWCRDYFLNCSALR---MADV--IRAELL-EI---IKRIEL---PY 651

  Fly   935 LKPPTDAQARFL--RQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSS-- 995
            .:|...::...|  ::.||:|...::||.|..:.            .|.....::.|.||..|
Human   652 AEPAFGSKENTLNIKKALLSGYFMQIARDVDGSG------------NYLMLTHKQVAQLHPLSGY 704

  Fly   996 VLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVP 1039
            .:.:|.||||::.:....:|.     :||..:.|.||..:..||
Human   705 SITKKMPEWVLFHKFSISENN-----YIRITSEISPELFMQLVP 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	178/855 (21%)
		DEXHc_DHX37	260..439	CDD:350740	65/182 (36%)
DHX32	XP_047281423.1	DEXHc_DHX32	62..237	CDD:350735	65/182 (36%)
		SF2_C_RHA	241..404	CDD:350178	38/275 (14%)
		HA2	507..596	CDD:461295	15/98 (15%)
		OB_NTP_bind	665..745	CDD:400182	24/96 (25%)