Protein Alignment kz and dhx29

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_697933.6
• Gene: dhx29 / 553505
• ZFINID: ZDB-GENE-130530-606
• Length: 1377
• Species: Danio rerio
• Alignment Length: 1165
• Identity: 298/1165 - (25%)
• Similarity: 492/1165 - (42%)
• Gaps: 270/1165 - (23%)

  Fly     1 MGKKVHNAKAR---QNPQTI----VDNSAV---------KKIQIDVDAVAGGNQVGYDEANALVL 49
            ||::....:.|   |..:|:    |.|:|:         ||..:..|.....|...:::|.|  .
Zfish   283 MGQRAAQDRIRVIQQEMKTLESHPVFNTAIKVKDTPKEEKKAAVVTDGKEELNFNLFEQAEA--A 345

  Fly    50 PSEKRATKIKVDKVQHVKILSKKQRKHLQAIVDKKKKKEGRA--QLLGDLAAVQIPEEELQQYTS 112
            |:||.|...|          .||:.|.::......:...|::  |.|.|.....:|:.....:..
Zfish   346 PAEKNAVAEK----------KKKEPKDIRNFDYTSRSWTGKSPKQFLIDWCRKNLPKSPPPSFNK 400

  Fly   113 IS-----------QVQTVGLKRLPTLDEYLAKKKERQAQVLAEKSSASGLRVNAIKG-SKRKLL- 164
            ::           |..|..|:..||    :..:...|||.|    .|:....|.:|| |..:||
Zfish   401 VAAGRYWKCKVRIQRPTDVLEVCPT----ILTEDGMQAQHL----GATLALYNLVKGQSVHQLLP 457

  Fly   165 ---------------VEEEEELQAKRK-----------------------NPNVISVEEDDEDS- 190
                           .|||:.|.|..|                       .|..:..:.:.|||
Zfish   458 PTYRDVWLEWRDGEQKEEEQTLLAINKPRDQFISRLLTRLKQQQSLQSQPEPQKLLQDAEPEDSW 522

  Fly   191 SSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPPIKK--LKPEPNPPACIHQTVYVPVHRTTEV 253
            .:.|..:|:.|...|       .|..|..:.|:...::  ||.:.:|.|             ..:
Zfish   523 ENLDTQEEQEPQCGA-------ASGGPAGLVVEEASRRLLLKLQASPLA-------------RRL 567

  Fly   254 QNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYE----AG-YAQHKMIGVTEP 313
            .:.|.:||:....:||:|.:..:.::::||||||||:||:|||:.|    || .||...:.||:|
Zfish   568 LDERKQLPVFQHREQVLEALRHHRVLVIAGETGSGKSTQIPQFILEELLAAGDTAQPCSVVVTQP 632

  Fly   314 RRVAAIAMSKRVAHEMNLPE------SEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSK 372
            ||::|::::.||:.|:...:      |...|.||.|...:.|||:.:.|.||||::::.|..|:.
Zfish   633 RRISAMSLACRVSQELGSEDGPGSMNSLCGYQIRMENRSSEATRLLYCTTGVLLRKLQQDRHLNS 697

  Fly   373 YSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKIPPPLL 437
            .:.||:||.|||||.:|.|:.:|..:|   |||.. |:||:||||:....|..    :....|::
Zfish   698 LTHIIVDEVHERSVQSDFLLTILKEVV---HKRAD-LRLILMSATVDCQKFAN----YFNRCPVV 754

  Fly   438 KVEARQFPVTI-HFQKRTPDDYVAEAYRKTLKIHNKLPEGGIL--------IFVTGQQEVN-QLV 492
            .:..|.|||.: |.     :|.|.|.             |.:|        .||..::||| .:.
Zfish   755 SIPGRTFPVEVFHL-----EDIVEET-------------GYVLEQDSEYSQKFVEEEEEVNIGIT 801

  Fly   493 RKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVE------DPKELEFDM-KRVIRNIRK 550
            :|..:|..:.....:|.|....:..|     :|..:|...      :|.::..|: ..::..:.|
Zfish   802 QKGGKTVQHQELIVRDSASGWDLGPE-----LDHFSSRTRHILQYMNPNKINMDLILDLLAYLDK 861

  Fly   551 SKKKFLAQMALPKINLDD----YKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGS 611
            |          |:.|..|    ..|||......:|:.                   |..:....|
Zfish   862 S----------PQFNAVDGAVLVFLPGLAHIQQLHDL-------------------LSTDKRFSS 897

  Fly   612 GQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYD 676
            ..|..|  :.|:|.|||:.|:..|...|.|.|..|:|||:|||.:|||.:.:|:|.||.|...|.
Zfish   898 KDRYKL--VALHSSLSSQDQSSAFTVPPAGVRKIVLSTNIAETGVTIPDVVFVIDTGRTKENRYH 960

  Fly   677 KLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQ 741
            :.:.:|:.|..:.|||||.||.|||||:..|.|:|||....: :.|.|:|.|:|.:.|:|:|.|.
Zfish   961 ESSQMSSLVEMFVSKASALQRQGRAGRVREGFCFRLYPKFRF-ESFIDYSIPEILRVPLEELCLH 1024

  Fly   742 -MRCMGIDRVVHFPFPSPPDQV-------QLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVI 798
             |:|         .:.||.|.:       |.||....:.:|..:...:.:...|.|    |||.:
Zfish  1025 IMKC---------EYGSPEDFLSRSLDAPQQQAVCNAVSLLRRIGACQQDTHTLTP----LGHHL 1076

  Fly   799 SRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAA 863
            :..||..:.||||........|.....:.||:|              :.:|.|....||.::..|
Zfish  1077 AALPVNVKIGKMLIFGAIFGCLEPIATIAAAMS--------------EKSPFATPMSRKEEANLA 1127

  Fly   864 SGNYQLL-GDPMVLLRAVGAAEYAGSQGRLPE--FCAANGLRQKAMSEVRKLRVQLTNEI-NLNV 924
            .....:. .|.|.:.:|......:.::|...|  :|..:.|.:.|:..:.:::.:|...: ....
Zfish  1128 KSALAVANSDHMTIYKAYLGWRSSRTEGTRAEMNYCRRHFLNRTALITIEEVKQELMRMVEQAGF 1192

  Fly   925 SDVELGVDPELKPPTDAQARF---------LRQILLAGMGDRVARKV--PLADIADKEERRRLKY 978
            ...:||..|..:|.|:.:|..         ::..|.||:.|.|.|.:  |..|:     :.|:..
Zfish  1193 VSSKLGRTPRPRPSTETKAPLSISTQDVCVVKATLTAGLYDNVGRILYSPSLDV-----QERVVC 1252

  Fly   979 AYNCADMEEPAFLHVSSVLR-QKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLY 1037
            ....|  :..|.:|.|||.| .:...|:::||..:.     :|:|::..|.|.|..:||:
Zfish  1253 VVETA--QGKAHVHPSSVNRFLQTHGWMLFQEKVKY-----SKVFLKDTTLISPLSMLLF 1305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	233/834 (28%)
		DEXHc_DHX37	260..439	CDD:350740	72/189 (38%)
dhx29	XP_697933.6	HrpA	573..>1191	CDD:441249	201/707 (28%)
		DEXHc_DHX29	574..756	CDD:350733	72/189 (38%)
		OB_NTP_bind	1223..1309	CDD:400182	26/95 (27%)