DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kz and ZCCHC17

DIOPT Version :9

Sequence 1:	NP_001284815.1	Gene:	kz / 31205	FlyBaseID:	FBgn0001330	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_001269495.1	Gene:	ZCCHC17 / 51538	HGNCID:	30246	Length:	263	Species:	Homo sapiens

Alignment Length:	164	Identity:	38/164 - (23%)
Similarity:	65/164 - (39%)	Gaps:	42/164 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 DKVQHVKILSKKQRK-HLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRL 124
            ||| .||::.::.:. .::..:..|...:|..:.| |...|.|.:||               :|.
Human    87 DKV-WVKLIGREMKNDRIKVSLSMKVVNQGTGKDL-DPNNVIIEQEE---------------RRR 134

  Fly   125 PTLDEYLAKKKERQAQVLAEKSSASGLRVNAIK-------GSKRKLLVEEEEELQAKR------- 175
            .:..:|..:|...:| ||.......|.:.:..|       |:|..|:.:||||.:..:
Human   135 RSFQDYTGQKITLEA-VLNTTCKKCGCKGHFAKDCFMQPGGTKYSLIPDEEEEKEEAKSAEFEKP 198

  Fly   176 ---KNPNVISVEED------DEDSSSSDEDDEEA 200
               :||:....:|.      |..||.||..|.|:
Human   199 DPTRNPSRKRKKEKKKKKHRDRKSSDSDSSDSES 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557
		DEXDc	279..418	CDD:238005
		P-loop_NTPase	369..>500	CDD:304359
		HELICc	619..704	CDD:197757
		HA2	774..859	CDD:214852
		OB_NTP_bind	915..1039	CDD:285018
ZCCHC17	NP_001269495.1	S1_pNO40	45..108	CDD:240191	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900