Protein Alignment kz and dhx38

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_957170.1
• Gene: dhx38 / 393850
• ZFINID: ZDB-GENE-040426-1144
• Length: 1258
• Species: Danio rerio
• Alignment Length: 1054
• Identity: 293/1054 - (27%)
• Similarity: 460/1054 - (43%)
• Gaps: 279/1054 - (26%)

  Fly    40 GYDE-ANALVLPSEKRATKIKVDKVQHVKILSKKQRKHL-----QAIVDKKKKKEGRAQLLGDLA 98
            |||| .|.|...|::...|       ..:||.|:.:|.:     |...|.::.:..|....|.:.
Zfish   361 GYDEFHNPLTSSSDEYVKK-------REQILQKQTQKRISAQKRQINEDNERWETNRMLTSGVVQ 418

  Fly    99 AVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLAEKSSASGLRVNAIKGSKRKL 163
            .::: :|:.::..:......|.....|.||..:...|:.: .|:..|.:.|.:.:.:.|||:
Zfish   419 RLEV-DEDFEEDNAARVHLLVHNLVPPFLDGRIVFTKQPE-PVIPVKDATSDMAIISRKGSQ--- 478

  Fly   164 LV----EEEEELQAKRKNPNV----------ISVEEDDEDSSSSDED---DEEAPAQSAPIAIPT 211
            ||    |::|..:|:.|:..:          |..:||..||.:..||   |..|..:.|
Zfish   479 LVRRHREQKERKKAQHKHWELAGTKLGDIMGIQKKEDGGDSKAVGEDGKVDYRAEQKFA------ 537

  Fly   212 PVSIAPPQIAVKPPIKKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINEN 276
                         ...|.|.|.:......:|:.          ..|..|||.|..||::..|.:|
Zfish   538 -------------DHMKEKSEASSDFAKKKTLL----------EQRQYLPIFAVRQQLLNIIRDN 579

  Fly   277 PIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEM--NLPESEVSYL 339
            .||||.|||||||||||.|:|:|.||..:.|:|.|:||||||::::|||:.||  ||.| ||.|.
Zfish   580 NIVIVVGETGSGKTTQLTQYLHEDGYTSYGMVGCTQPRRVAAMSVAKRVSEEMNSNLGE-EVGYA 643

  Fly   340 IRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHK 404
            ||||...:..|.||:||||:||:|...:..|..||.:|:|||||||:.||:|.|||..:|    .
Zfish   644 IRFEDCTSEKTMIKYMTDGILLRESLRESDLDHYSAVIMDEAHERSLNTDVLFGLLREVV----S 704

  Fly   405 RGQPLKLIIMSATL---RVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKT 466
            |...||||:.|||:   :.:.|..|..:|.||       .|.|||.|.|.|...:|||..|.::.
Zfish   705 RRSDLKLIVTSATMDSDKFASFFGNVPIFHIP-------GRTFPVDILFSKTPQEDYVEAAVKQA 762

  Fly   467 LKIHNKLPEGGILIFVTGQQEV----NQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDA 527
            |:||.....|.||||:.||:::    :|:|.:|
Zfish   763 LQIHLSGMVGDILIFMPGQEDIEVTSDQIVERL-------------------------------- 795

  Fly   528 ASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEG 592
                                                              ||:...|
Zfish   796 --------------------------------------------------ADLENAP-------- 802

  Fly   593 LEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLT 657
                                   .|.|||:||.|.|:.|.:||...|||.|.|:|:||:||||||
Zfish   803 -----------------------ALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 844

  Fly   658 IPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCF 722
            :..|.:|||.|..|.::::...|:.|..|...|:|:|:||||||||...|.|||||:.:.:.:..
Zfish   845 VDGIMFVVDSGYCKLKVFNPRIGMDALQVYPISQANANQRAGRAGRTGPGQCYRLYTQSAFKNEM 909

  Fly   723 EDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTDL 787
            ...:.|:||:..:.:::|.::.:|:..::.|.|..||.:..:..:..:|.:||||     :||.
Zfish   910 LTTTIPEIQRTNLANVVLLLKSLGVQDLLLFHFMDPPPEDNMLNSMYQLWILGAL-----DNTG- 968

  Fly   788 PPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLI-------ETGVQRDE 845
              |:|..|.::..||:.|...|||.:|...:.....:.:|:.|||..:..       |:...|::
Zfish   969 --ALTPTGRLMVEFPLDPALSKMLIVSCDMSCSADILIIVSMLSVPSIFYRPKGREEESDQVREK 1031

  Fly   846 DVAPGANR--FHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSE 908
            ...|.::.  :......| .:.||..:                        :|..:.:..|||.:
Zfish  1032 FSVPESDHLTYLNVYLQW-KNNNYSSI------------------------WCNDHFIHTKAMRK 1071

  Fly   909 VRKLRVQLTN-----EINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIA 968
            ||::|.||.:     ::||    :..|.|.::.......|.|.:...|.|:|:.|..:..:
Zfish  1072 VREVRAQLKDIMVQQKMNL----ISCGSDWDVIRKCICAAYFHQAAKLKGIGEYVNVRTGM---- 1128

  Fly   969 DKEERRRLKYAYNCADMEEPAFLHVSSVL--RQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEP 1031
                               |..||.:|.|  ....|:::||.|...     :||.:::.:||::.
Zfish  1129 -------------------PCHLHPTSALFGMGYTPDYIIYHELVM-----TTKEYMQCVTAVDG 1169

  Fly  1032 EWLLLYVPLLCNIR 1045
            |||....|:..:|:
Zfish  1170 EWLAELGPMFYSIK 1183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	244/811 (30%)
		DEXHc_DHX37	260..439	CDD:350740	93/183 (51%)
dhx38	NP_957170.1	HrpA	563..>1177	CDD:441249	242/803 (30%)