Protein Alignment kz and Dhx8

DIOPT Version :9

• Sequence 1: NP_001284815.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_006247348.1
• Gene: Dhx8 / 287727
• RGDID: 1310723
• Length: 1242
• Species: Rattus norvegicus
• Alignment Length: 1117
• Identity: 298/1117 - (26%)
• Similarity: 468/1117 - (41%)
• Gaps: 295/1117 - (26%)

  Fly     5 VHNAKARQ-----NPQTIVDNSAVKKIQI-------------DVDAVAGGNQVGYDEANALVLPS 51
            ||.::.|:     |...:|......|:::             |||... |..:..:....||..:
  Rat   317 VHISELRREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQET-GEDLNPNRRRNLVGET 380

  Fly    52 EKRATKIKVDKVQHVKILS-------KKQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQQ 109
            .:..:....|:..|:.::|       ..:||.|..|.|.:|     .::...:||..:.:||...
  Rat   381 NEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEK-----WEIKQMIAANVLSKEEFPD 440

  Fly   110 YTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLAE---------KSSASGLRVNAIKGSKRKL-- 163
            :.     :..|:  ||.:|:  .:.::.:.:::.|         |.|.....:..:|.....|
  Rat   441 FD-----EETGI--LPKVDD--EEDEDLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQ 496

  Fly   164 -------LVEEEEEL-QAKRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAI------PTP-- 212
                   |.:|..|| ||:|                       ||...|.|:.:      |.|
  Rat   497 AAMMQSALAKERRELKQAQR-----------------------EAEMDSIPMGLNKHWVDPLPDA 538

  Fly   213 -----------VSIAPPQIAVKPPIKKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEE 266
                       :.:.|..|   |..||.....|..:...:|       ...:...|..|||...:
  Rat   539 EGRQIAANMRGIGMMPNDI---PEWKKHAFGGNKASYGKKT-------QMSILEQRESLPIYKLK 593

  Fly   267 QQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEMN- 330
            :|:::.:::|.|:||.||||||||||:.|:|.||||.....||.|:||||||::::|||:.|..
  Rat   594 EQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGC 658

  Fly   331 LPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLL 395
            ....||.|.||||...:|.|.||:||||:||:|...|..|::|::|:|||||||:::||:|.|||
  Rat   659 CLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLL 723

  Fly   396 SRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVA 460
            .:.|..|    |.:|||:.||||....|::    :....|:..:..|.:||.|.:.|....||:.
  Rat   724 KKTVQKR----QDMKLIVTSATLDAVKFSQ----YFYEAPIFTIPGRTYPVEILYTKEPETDYLD 780

  Fly   461 EAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETID 525
            .:....::||...|.|.||:|:|||:|                                    ||
  Rat   781 ASLITVMQIHLTEPPGDILVFLTGQEE------------------------------------ID 809

  Fly   526 DAASTV-EDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDE 589
            .|...: |..|.|..|:..:|
  Rat   810 TACEILYERMKSLGPDVPELI-------------------------------------------- 830

  Fly   590 QEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAET 654
                                         :||:||.|.||.|.|||.|.|.|.|..|::||:|||
  Rat   831 -----------------------------ILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAET 866

  Fly   655 SLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYN 719
            ||||..|.||||.|..|.::|:..||:...|||..|:|.|.||||||||...|.|||||:...|.
  Rat   867 SLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYR 931

  Fly   720 DCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTEN 784
            |.....:.|:||:..:...:|.::.|||:.::.|.|...|....|..|..:|..||||
  Rat   932 DEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGAL------- 989

  Fly   785 TDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAP 849
             |....:||||..::.||:.|...|||.:|.........:.:|:.||||.|
  Rat   990 -DDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNV-------------- 1039

  Fly   850 GANRFHRKRQSWAASGN-----YQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEV 909
                |:|.:...|.:..     :|..||.:.||....:  :..::...| :|..|.::.:::...
  Rat  1040 ----FYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNS--WKNNKFSNP-WCYENFIQARSLRRA 1097

  Fly   910 RKLRVQLTNEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERR 974
            :.:|.|:...::.:..||.......::         :::.:.:|.....|:|.|
  Rat  1098 QDIRKQMLGIMDRHKLDVVSCGKSTVR---------VQKAICSGFFRNAAKKDP----------- 1142

  Fly   975 RLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVP 1039
              :..|.....::..::|.||.|..:.||||:|.|...     :||.::|.:|.|:|.||:.:.|
  Rat  1143 --QEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVL-----TTKEYMREVTTIDPRWLVEFAP 1200

  Fly  1040 LLCNIREVREDP 1051
            ....:    .||
  Rat  1201 AFFKV----SDP 1208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	245/822 (30%)
		DEXDc	279..418	CDD:238005	74/139 (53%)
		P-loop_NTPase	369..>500	CDD:304359	46/130 (35%)
		HELICc	619..704	CDD:197757	48/84 (57%)
		HA2	774..859	CDD:214852	24/84 (29%)
		OB_NTP_bind	915..1039	CDD:285018	26/123 (21%)
Dhx8	XP_006247348.1	S1_DHX8_helicase	287..365	CDD:240189	9/48 (19%)
		DEXDc	583..768	CDD:214692	88/192 (46%)
		DEXDc	604..742	CDD:238005	75/141 (53%)
		HELICc	767..924	CDD:238034	75/265 (28%)
		HA2	986..1068	CDD:214852	28/107 (26%)
		OB_NTP_bind	1102..1201	CDD:285018	26/125 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820