Protein Alignment kz and prp16

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_595890.2
• Gene: prp16 / 2540006
• PomBaseID: SPBC1711.17
• Length: 1173
• Species: Schizosaccharomyces pombe
• Alignment Length: 1037
• Identity: 289/1037 - (27%)
• Similarity: 445/1037 - (42%)
• Gaps: 278/1037 - (26%)

  Fly    72 KQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKE 136
            :.|.|....::|:||.      |...|:.:..|..:.:.   :::.|.|:.:.|.|:...:..:|
pombe   314 EDRAHEAEFIEKQKKH------LSIEASDRFKENSMWEK---NRMITSGVSKAPGLESDYSLMEE 369

  Fly   137 RQAQVL-----------AEKSS------------ASGLRVNAIKGSKRKLLVEEEEELQAKRKNP 178
            |:..:|           ||.||            .|.|.:||..||:   ||.|..|.:.::|..
pombe   370 RRVHLLVDELRPHFLDGAEFSSKKVGDITSVRDPQSDLAINARLGSR---LVRERREFRERQKAA 431

  Fly   179 ------------NVISVEEDDEDSSSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPPIKKLKP 231
                        ||:.::         |.:||:|.|.:      |||.:|...   :...||
pombe   432 SAATSLAGTSLGNVMGLK---------DSNDEDAKAGT------TPVKVAGRS---EQSNKK--- 475

  Fly   232 EPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQF 296
                     .|.:.   ||...:..|..||..|..:|::..|.:|.::||.|||||||||||.||
pombe   476 ---------DTEFA---RTKSYREQREFLPAFAVREQLLSVIRDNQVLIVVGETGSGKTTQLAQF 528

  Fly   297 LYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNLP-ESEVSYLIRFEGNVTPATRIKFMTDGVL 360
            |||.||.::.|||.|:||||||::::|||:.||.:. .|.|.|.||||....|.|.||:||||||
pombe   529 LYEDGYHRNGMIGCTQPRRVAAMSVAKRVSEEMGVRLGSTVGYSIRFEDVTGPDTVIKYMTDGVL 593

  Fly   361 LKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATL---RVSD 422
            |:|......|.||||||:|||||||:.||||:|||.:::    .|.:.:||::.|||:   :.||
pombe   594 LRESLMQNNLEKYSVIIMDEAHERSLNTDILMGLLKKVL----SRRRDIKLLVTSATMNSQKFSD 654

  Fly   423 FTENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQE 487
            |......|.||       .|.:||.|.|.|....|||..|.|:.|:||...|.|.||:|:|||::
pombe   655 FFGGAPQFTIP-------GRTYPVDIMFAKAPCSDYVEAAVRQVLQIHLSQPAGDILVFMTGQED 712

  Fly   488 VNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSK 552
            :                             |...|.|.|
pombe   713 I-----------------------------EATCEIIAD-------------------------- 722

  Fly   553 KKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPL 617
                      ::|             .:|:.|                               .|
pombe   723 ----------RLN-------------QLHDAP-------------------------------RL 733

  Fly   618 WVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVS 682
            .:||:||.:.::.|.:||.....|.|..||:||:||||||:..|.||||.|..|.::|:...|:.
pombe   734 SILPIYSQMPADLQAKIFDSAEPGVRKVVVATNIAETSLTVHGISYVVDTGYCKLKMYNSKLGID 798

  Fly   683 AFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVY-NDCFEDFSQPDIQKKPVEDLMLQMRCMG 746
            ...||..|:|:|:||||||||...|..||||:...| .:.||. :.|:||:..:.:.:|.::.:|
pombe   799 TLQVTPISQANANQRAGRAGRTGPGIAYRLYTEMAYIREMFET-TLPEIQRTNLSNTVLILKSLG 862

  Fly   747 IDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKML 811
            ::.:..|.|...|....|.|:...|..||||        |....:|.||..:|.||:.|...|::
pombe   863 VEEISDFDFMDRPPNDTLMASLYELWTLGAL--------DNFGKLTTLGKKMSLFPMDPSLSKLI 919

  Fly   812 ALSHQQNLLPYTVCLVAALSVQEVLI-------ETGVQRDEDVAPGANRFHRKR--QSWAASGNY 867
            .::.........:.:|:.|||..|..       |:...|::...|.::......  |.|..:|
pombe   920 IIAEDYKCTEEIITIVSMLSVPSVFYRPKERAEESDAAREKFNVPESDHLMLLNIYQHWQRNG-- 982

  Fly   868 QLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVD 932
                             |:.|      :|:.:.|..|.:...|.:|.||...::.....:|...|
pombe   983 -----------------YSNS------WCSKHFLHSKTLKRARDIRQQLVEIMSKQKISLESVSD 1024

  Fly   933 PELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVL 997
            .::.......|.|.:.....|:|:                     |.:..:.|  |..|||:|.|
pombe  1025 WDIVRRVLCSAYFHQAACAKGIGE---------------------YVHLRSGM--PCHLHVTSSL 1066

  Fly   998 RQKA--PEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLCNIREVREDPAPRFDK 1057
            ....  |::|||.|...     ::|.::..:|:::|.||..:..:..:::|...:....:|:
pombe  1067 YGLGYLPDYVIYHELVL-----TSKEYMNIVTSVDPYWLAEFGGVYYSVKERFRNETESYDR 1123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	242/814 (30%)
		DEXHc_DHX37	260..439	CDD:350740	93/182 (51%)
prp16	NP_595890.2	HrpA	492..>1087	CDD:441249	235/776 (30%)