Protein Alignment kz and ddx-35

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_497420.1
• Gene: ddx-35 / 175308
• WormBaseID: WBGene00022056
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 916
• Identity: 260/916 - (28%)
• Similarity: 382/916 - (41%)
• Gaps: 247/916 - (26%)

  Fly   150 GLRVNAIKGS-KRKLLVEEEEELQAKRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAIPTPV 213
            |.|....||: .|:.....::...|.|..|.:.                ||...::|..|
 Worm     8 GHRQEPRKGAGARRGFARPDDSADAPRTGPLIF----------------EERSTENAGAA----- 51

  Fly   214 SIAPPQIAVKPPI-KKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENP 277
                      ||| ::||...||.|.::            :|..|:||||......::.......
 Worm    52 ----------PPIEEQLKVHNNPYASLN------------IQQQRIRLPIFKNRGHILYMCERYR 94

  Fly   278 IVIVAGETGSGKTTQLPQFLYEAGY-AQHKMIGVTEPRRVAAIAMSKRVAHEMN-LPESEVSYLI 340
            .:|:.||||.||:||:||||.|||: |..:.|.:|:|||||.:.::.|||.|.: :...:|.|.:
 Worm    95 TIIIVGETGCGKSTQVPQFLLEAGWAADGRQIVITQPRRVAVVTLATRVAEEKDCILGHDVGYTV 159

  Fly   341 RFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKR 405
            ||:......|::||||||:||:||..|.||||||:|::|||||||..||||:|||.:|:.:|:
 Worm   160 RFDDVSDKDTKVKFMTDGLLLREILADPLLSKYSIIMIDEAHERSCNTDILLGLLRKIIQIRN-- 222

  Fly   406 GQPLKLIIMSATLRV---SDF---TENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYR 464
              .|::|:.||||..   .||   .|.....|....::.||.|..||.:|..|.:..||...|..
 Worm   223 --DLRIIVSSATLDAELFKDFFEMNETGNSDKDTAGIISVEGRTHPVAVHHTKTSVPDYCQSAVD 285

  Fly   465 KTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAAS 529
            ..:.||.....|.||:|:|||.||..:..|||
 Worm   286 TVINIHKHENPGDILVFLTGQDEVEDVCEKLR--------------------------------- 317

  Fly   530 TVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLE 594
                  ||..::|...|
 Worm   318 ------ELAGNLKNCDR------------------------------------------------ 328

  Fly   595 EDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIP 659
                                  |||:|.|..|.:.:|.:.|...|.|.|..||:||:||.|:|||
 Worm   329 ----------------------LWVVPCYGALPAREQMKAFDSTPHGTRKVVVATNIAEASITIP 371

  Fly   660 HIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFED 724
            .|.||:|.|..|.|......||...:....|||||:|||||||||..|.|||||..:.    ||.
 Worm   372 GICYVIDTGYVKLRAQHAANGVETLMRVTVSKASAEQRAGRAGRIRPGKCYRLYPESE----FER 432

  Fly   725 FSQ---PDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTD 786
            |::   |:||:..:...:||::.:|:..|..|.:.|||....:......|..|||::    |.:.
 Worm   433 FAEGTVPEIQRCQMASTILQLKALGVQNVHRFHYLSPPPSWAMINGLELLYALGAID----ETSQ 493

  Fly   787 LPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDE-DVAPG 850
            |   .:.||..::.||:.|...|.|..|.:.......|.:||.:.:|:|.|....||.: ||.
 Worm   494 L---TSPLGLQMAEFPLPPMHSKCLLKSAEFGCSTEMVTIVAMMQIQDVFITPYRQRHQADVI-- 553

  Fly   851 ANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQ 915
                   |:.:|...     ||.|.:|...  .::. ..||..::|:.:.:..:.:.....:|.|
 Worm   554 -------RKKFAVEE-----GDHMTMLNVF--TKFV-ENGRSKKWCSDHFVNYRGLMRADNVRSQ 603

  Fly   916 LTN-----EIN-------LNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIA 968
            |..     ||.       :|.|:                  .:||.|:.|...:.|:    ....
 Worm   604 LVRLLKRFEIEKVSSRGLINCSE------------------NIRQCLVTGFFSQAAQ----YHYT 646

  Fly   969 DKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEW 1033
            .|....:..:.:|       .:...|.:.::..|:|||:.|..:    ||    ||.:|.|||||
 Worm   647 GKYMTVKESFPFN-------MYKGSSIMFKKDYPKWVIFTEVMQ----DS----IRDVTVIEPEW 696

  Fly  1034 LLLYVP 1039
            |....|
 Worm   697 LYELAP 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	237/804 (29%)
		DEXHc_DHX37	260..439	CDD:350740	80/186 (43%)
ddx-35	NP_497420.1	HrpA	95..>703	CDD:441249	234/786 (30%)