Protein Alignment kz and LOC1281840

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_061505255.1
• Gene: LOC1281840 / 1281840
• VectorBaseID: AGAMI1_014012
• Length: 1210
• Species: Anopheles gambiae
• Alignment Length: 1071
• Identity: 287/1071 - (26%)
• Similarity: 443/1071 - (41%)
• Gaps: 337/1071 - (31%)

  Fly   248 HRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTE 312
            ::..:::.|:..||:....::::|.:....:|::||:||.||:||:||:||.|||   :.|..|:
Mosquito   170 NKLRKLRQAQANLPVAKHREEIVEAVRNERVVVLAGDTGCGKSTQVPQYLYRAGY---EGIACTQ 231

  Fly   313 PRRVAAIAMSKRVAHEMNLPE--SEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSV 375
            |||:|.|::|||||||: |.|  :||.|.||||.:....|:|.|:|:|:||:::.::..|.:|||
Mosquito   232 PRRIACISLSKRVAHEL-LAEYRTEVGYQIRFERSKNTNTKILFITEGLLLRQLASEDNLQQYSV 295

  Fly   376 IILDEAHERSVYTDILVGLLSRIVPLRHKRGQP-LKLIIMSATLRVSDFT-----ENTRLFKIPP 434
            |||||.|||.::.|.|:|:...::     |.:| |||::||||:.:..|.     |..|:.::|
Mosquito   296 IILDEVHERHLHGDFLLGIAKCLI-----RARPDLKLVLMSATINIKLFADYFSEEEARIIEVP- 354

  Fly   435 PLLKVEARQFPVTIHF----------------QKRTPDDYVA-EAYRKTLK-IHNKLP---EGGI 478
                  .|.||:.:|:                .|||..|.:: |.|.:.|: |..|.|   :|.:
Mosquito   355 ------GRLFPIKLHYMPQLQDVPMVSGGAGGSKRTQSDRLSPEPYIQILQLIDQKYPPTEKGDV 413

  Fly   479 LIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKR 543
            |||::|..|:..:|                                 |||
Mosquito   414 LIFLSGLNEITAIV---------------------------------DAA--------------- 430

  Fly   544 VIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESG 608
              |...:..|.::
Mosquito   431 --REYNEKNKNWI---------------------------------------------------- 441

  Fly   609 MGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTR 673
                      :|||:|.||..:|:::|...|||.|.|:||||:||||:||..|::|||.|:.|..
Mosquito   442 ----------ILPLHSTLSIAEQDKVFDYAPDGMRKCIVSTNIAETSVTIDGIRFVVDSGKVKEM 496

  Fly   674 LYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDL 738
            .||..|.:......:.|||||:||.|||||...|.|||||:...:.| |:.:|..:|.|.|:|.|
Mosquito   497 SYDPTTKMQRLKEFWISKASAEQRKGRAGRTGPGICYRLYAEKQFYD-FDAYSTAEILKVPLESL 560

  Fly   739 MLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPV 803
            :|||..||:.....|||..||   .:...|..::.|...| |.||:..|.|    ||..:::.||
Mosquito   561 LLQMISMGLPNARLFPFVEPP---PMDNVENAIVNLKEAE-ALTEDEKLTP----LGKALAKIPV 617

  Fly   804 APRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQ 868
            ....||||.:......|...:.|.||||||              :|..||.:|..:...|..:.:
Mosquito   618 DIGIGKMLLMGCVFQQLQPVLTLAAALSVQ--------------SPFTNRAYRDPECERARKSLE 668

  Fly   869 L-LGDPMVLLRA----VGAAEYAGSQGRLPE----------FCAANGLRQKAMSEVRKLRVQ--- 915
            . .|||:.||.|    :...::....||..:          :|...||.::...|:.|||.|
Mosquito   669 SDHGDPITLLNAYKEWLEIKQHRTDYGRRDDGDRRSESSKVWCRRRGLEEQRFYEITKLRNQFQD 733

  Fly   916 -------LTNEINLNVSDVELGVD-------PELKPPTDAQARFLRQILLA---GMGD------- 956
                   :..:.|.::|..|..:.       .||:.....:|...|::|.:   |:|:
Mosquito   734 LLQDCGLMETQNNDHLSSAERAIRNGELRQLKELRKAHRMEAPRKRKLLKSDPWGLGEDGEEEAD 798

  Fly   957 --RVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDST 1019
              ||       ||.|.|.|                ..|.||.|:             .|.:| :|
Mosquito   799 DGRV-------DIRDVEFR----------------LSHDSSKLQ-------------HLVSG-AT 826

  Fly  1020 KMFIRGITAIEPEWLLLYVPLLCNIREVRE-----DPAPRFDKTSGK--IFCHVDATFGKSGWEL 1077
            ....|.:..::   |:|...|...:....|     ..:.:|..|..|  :..|..:.||.:...|
Mosquito   827 ACSYRDLMTLK---LILVSGLYPQVAIADEFNYCKSLSEQFFHTRAKPYVSLHPMSFFGNNAQIL 888

  Fly  1078 PLGEVEM-----------PLSEK--ACCY-------------------------FGMFLLDGEVC 1104
            .|.:.|:           |||.:  ..||                         |...:.....|
Mosquito   889 QLTDSEIEEKPPMYKSRQPLSSRHQIVCYLTLLETNKSYLTNTLRMPAAQTLLLFAHTIETNASC 953

  Fly  1105 SRLA-------DFRSKLKSTPASVIKS------WSSMNNKVLRFK-RAL-------ITKQIHNRQ 1148
            ||:.       ||.:. :|..|.::|:      |    |::|..| :||       :||.  .|.
Mosquito   954 SRIVCDAWLCLDFPAP-ESGQALLLKATKLRRLW----NRLLAEKLKALTITADGELTKA--ERN 1011

  Fly  1149 ALIDQWNSDPHFLLEEYQNLLYDVALSELTP 1179
            ..|||.|.:....|.:|.|......:.:|.|
Mosquito  1012 VSIDQMNRELWSSLAQYMNTEVCYTMKKLLP 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	249/890 (28%)
		DEXHc_DHX37	260..439	CDD:350740	77/186 (41%)
LOC1281840	XP_061505255.1	None