Protein Alignment kz and Rhau

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_061510121.1
• Gene: Rhau / 1277741
• VectorBaseID: AGAMI1_000202
• Length: 1051
• Species: Anopheles gambiae
• Alignment Length: 1132
• Identity: 272/1132 - (24%)
• Similarity: 443/1132 - (39%)
• Gaps: 329/1132 - (29%)

  Fly    83 KKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLAEKSS 147
            :|:::|.|     |...:.:|..::|:..:..|:.. |:::.....|:  .:.|....|...:.
Mosquito   161 QKRQREKR-----DAVDITLPRWQIQEIRNNLQMHR-GIEQSDIYREF--AENENMRSVFRNEY- 216

  Fly   148 ASGLRVNAIKGSKRKLLVEEEEELQAKRKNPNVISVEEDDEDSSSSDED---DEEAPAQSAPIAI 209
               |||.:      |.|.|...|..|:|:|           .|.|:.|.   |||...|
Mosquito   217 ---LRVIS------KTLQESMVEAVARREN-----------SSGSAYEPGLLDEELLEQ------ 255

  Fly   210 PTPVSIAPPQIAVKPPIKKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETIN 274
                        ....::.:.|                     :...|.|||.......:::.|.
Mosquito   256 ------------YDRTVRSMHP---------------------LSEFRRRLPAYQSRTTILDMIE 287

  Fly   275 ENPIVIVAGETGSGKTTQLPQFLYE----AGYAQHKMIGVTEPRRVAAIAMSKRVAHEMN--LPE 333
            .|.::::.||||||||||:||::.|    .|......|..|:|||::||.:::|||.|.|  |..
Mosquito   288 RNQVILIKGETGSGKTTQVPQYILEEASACGRGARCRILCTQPRRISAITLARRVAEERNERLGN 352

  Fly   334 SEVSYLIRFEGNVTPATR-------IKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDIL 391
            | |.|.||.|     |.|       |.|.|.|::|..:::|.|||:|:.::|||.|||.|.||:|
Mosquito   353 S-VGYQIRLE-----AERPRQAGGSIMFCTTGIVLTIMQSDPLLSEYTHLVLDEIHERDVITDLL 411

  Fly   392 VGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTE---NTRLFKIPPPLLKVEARQFPVTIHFQKR 453
            :.::..::|.|    :.|::|:|||||....|::   |.       |.:::....:|||
Mosquito   412 LAIIRMVLPYR----KDLRVILMSATLTAETFSQYFNNC-------PTVEIRGITYPVT------ 459

  Fly   454 TPDDYVAEAYRKTLKIHNKLPEGGILIFVTG--------QQEVNQLVRKLRRTFPYHHAPTKDVA 510
               :|..|.....||.:....:.|......|        |..:.....::|..:|   ||.....
Mosquito   460 ---EYYLEDILDELKFYTFEDKYGQKPHFRGRGRQDDPFQAMIEPYCSEIRGRYP---APVLRAL 518

  Fly   511 KNGKVSEEEKEETI-----------DDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKI 564
            :| ..||..:.|.|           .|.|..|..|..::      |.|:
Mosquito   519 QN-PGSESNQNELIVELLYYITCSKPDGAILVFLPSYMQ------ITNV---------------- 560

  Fly   565 NLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSE 629
                ||:        ::|.|                          ...:..|.|.||:|.|.:.
Mosquito   561 ----YKM--------INEHP--------------------------YLSKARLLVSPLHSKLPTR 587

  Fly   630 KQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASA 694
            :|..:|...|||.|..::|||:||||:||..|.|||:.||.|...|:  .|||.....:.|.::.
Mosquito   588 EQTAVFDRPPDGVRKIILSTNIAETSITIDDIVYVVNAGRHKLNRYE--DGVSVLRDEWISVSNE 650

  Fly   695 DQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFP---FP 756
            .||.|||||:..|.||.|||.. ....|::..:|:|.:..:|:::||::.:.:.....|.   ..
Mosquito   651 IQRKGRAGRVREGICYHLYSRG-RKRTFQENVEPEIVRVALEEVILQIKILQLGEARAFMAHLLD 714

  Fly   757 SPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLP 821
            .|.|.:    .|..|.:|..|.....|.     .:|.||..::|.|:.||.|||:.|:...:.:.
Mosquito   715 KPSDGI----IESSLELLNRLNAIDDEQ-----KLTPLGFHLARLPMDPRTGKMILLASIFSCID 770

  Fly   822 YTVCLVAALSVQEVLIE-TGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEY 885
            ....:.|:|:.:..... .|.:::.|      |..||....:||       |.::|...:  ||:
Mosquito   771 PITSIAASLTFKTAFYRPLGKEKEVD------RIKRKFAQDSAS-------DHIMLANVI--AEW 820

  Fly   886 AGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEIN----LNVSDVELGVDPELKPPTDAQA--- 943
            . .|.....||..:.|....:.::..::.|....::    ..|:..:.|       |.:..|
Mosquito   821 R-EQPNKGSFCGRHFLNGATLQQLANMKEQFAEYLHTAKFTAVARSDAG-------PNNRHAGNL 877

  Fly   944 RFLRQILLAGMGDRVA--RKV----------PLADIADKEERRRLKYAYNCADMEEPAFLHVSSV 996
            ..||.|:.||:...||  |||          |:.:|   |...|             |.:|..||
Mosquito   878 ELLRAIVGAGLYPNVAFVRKVIRSRNSPDGRPILNI---EGLGR-------------AEIHPGSV 926

  Fly   997 LRQKA---PEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLCNIREVREDPAPRFDKT 1058
            ...:.   ..:|:|   |::|..::..:|  ..|.:.|..||.:..
Mosquito   927 NGNRGVFHSNFVVY---YDMQKINALTIF--DTTVVNPFPLLFFGD------------------- 967

  Fly  1059 SGKIFCHVDATFGKSGWELPLGEVEMPLSEKAC--CYFGMFLLDGEVCSRLADFRS-------KL 1114
                 |||:.   ::..||      :.::...|  |       |.:..:.:.|.|:       |.
Mosquito   968 -----CHVET---ENDHEL------ISIAGHYCLKC-------DKDTYNLIQDLRTGFNLFLQKQ 1011

  Fly  1115 KSTPASVIKSWSSMNNKVLRFKRALIT 1141
            ..:|:.|  .|||...::||....|||
Mosquito  1012 ICSPSPV--DWSSREGELLRAIIRLIT 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	223/871 (26%)
		DEXHc_DHX37	260..439	CDD:350740	71/194 (37%)
Rhau	XP_061510121.1	None