Protein Alignment kz and kz

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_312236.6
• Gene: kz / 1273275
• VectorBaseID: AGAMI1_001604
• Length: 1224
• Species: Anopheles gambiae
• Alignment Length: 1253
• Identity: 646/1253 - (51%)
• Similarity: 831/1253 - (66%)
• Gaps: 97/1253 - (7%)

  Fly     1 MGKKVHNAKARQNPQTIVDNSAVKKIQIDVDAVAGGNQVGYDEANALVLPSEKRATKIKVDKVQH 65
            |||:..|.|.||..:||:|:|..|||::|.  ..|....|.|.:|.|||||:||.||||.|:...
Mosquito     1 MGKRRFNEKGRQKVETIIDDSETKKIKLDF--APGDEYGGQDNSNVLVLPSKKRETKIKKDRTVV 63

  Fly    66 VKILSKKQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEY 130
            .|||||||||.|:.|||:|||||.|:.|:..|.|||..:::|..:..:|:|||.|||:
Mosquito    64 TKILSKKQRKRLEKIVDQKKKKENRSSLIASLVAVQASKDDLSGFRKLSEVQTKGLKQ------- 121

  Fly   131 LAKKKERQAQVLAEKSSASGL-RVNAIKGSKRKLLV----------------------------- 165
             ..|:::........:..:|: ::.::.||:||.|.
Mosquito   122 -HFKEQKYGVTYVNNAKEAGVAKIKSLVGSRRKRLALLRQAGPASVEEVEGEYDPNVVGLNDPSS 185

  Fly   166 ---EEEEELQAKRKNPNVISVEEDDEDSSSSDEDDE----EAPAQSAPIAIPTPVSIAPPQIAVK 223
               |.|||::.:.:..|....||.:::|:..||::|    :...:|........|..|||:...:
Mosquito   186 SEDESEEEVEEEGEEGNEQEEEESEQESAQEDENEEVDKNQPEQESITEESSKKVENAPPEDVKQ 250

  Fly   224 PPIKKLKPE--PNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETG 286
            |..:|.||.  ...||     .|:.|.|...:|.|||:||||.|||.:||||:||.|.|:|||||
Mosquito   251 PNGEKEKPTVVDRKPA-----TYIHVERDPAIQAARLKLPILGEEQIIMETISENKITILAGETG 310

  Fly   287 SGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNLPESEVSYLIRFEGNVTPATR 351
            ||||||:|||||||||.:..:|||||||||||::|||||||||||....||||||:|||||..|:
Mosquito   311 SGKTTQIPQFLYEAGYGERGLIGVTEPRRVAAVSMSKRVAHEMNLSTDVVSYLIRYEGNVTDRTK 375

  Fly   352 IKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRG-QPLKLIIMS 415
            ||||||||||||||.||||:|||.||||||||||||||||:|||||||.||.||| .||::||||
Mosquito   376 IKFMTDGVLLKEIEVDFLLNKYSCIILDEAHERSVYTDILMGLLSRIVRLREKRGNNPLRVIIMS 440

  Fly   416 ATLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILI 480
            |||||.|||||.:||...||::.:::||||||:||.|.|||||:.||:.||:|||.|||:||||:
Mosquito   441 ATLRVQDFTENKKLFLDTPPVINIDSRQFPVTVHFNKTTPDDYLREAFLKTVKIHTKLPDGGILV 505

  Fly   481 FVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVI 545
            |:|||:|||.:|||||:.||..  ..|:..:.||..:|:|||.:.|        :|.|||  .|.
Mosquito   506 FLTGQKEVNTMVRKLRKMFPLR--GDKEGVRTGKKVDEKKEEVVRD--------EEDEFD--NVY 558

  Fly   546 R--------NIRKSKKKFLAQM-ALPKINLDDYKLPG-DDTEADMHEQPDEDDEQEGLEEDNDDE 600
            |        ..:.||::...|: .||:||||.|.||. ||||.|..|:.|...|.:  .:|:|||
Mosquito   559 RGKPAHKPPKAKSSKRQKRDQLPVLPQINLDAYDLPHVDDTEGDRAEENDTASELD--SDDDDDE 621

  Fly   601 LGLEDESGMGSGQR--QPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKY 663
            |...:.|...|..|  ||||||||||:||.:||..||.|.|:|.|||||:|||||||||||.|||
Mosquito   622 LNAANLSASVSELRKSQPLWVLPLYSMLSPDKQQLIFQPPPEGARLCVVATNVAETSLTIPDIKY 686

  Fly   664 VVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQP 728
            |||.|||||:||||.|||:||||||||||||:||||||||::.|||||||||||:||.|.:|:.|
Mosquito   687 VVDTGRQKTKLYDKTTGVTAFVVTYTSKASANQRAGRAGRVAPGHCYRLYSSAVFNDEFVEFAPP 751

  Fly   729 DIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVA-------KTENTD 786
            ::|:|||:.|||||:|||||:|::||||||||.|||.:||:||:.|||||..       |.:...
Mosquito   752 EVQQKPVDGLMLQMKCMGIDKVLNFPFPSPPDPVQLMSAEQRLLQLGALEQVIVRNGGQKVQKNQ 816

  Fly   787 LPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGA 851
            ....||.||..::.||||||||||||||||..||||.:||||||||||||.|..:..:.:.....
Mosquito   817 TLTRVTELGRTMAAFPVAPRFGKMLALSHQHALLPYVICLVAALSVQEVLEEVSLSEEANNTESG 881

  Fly   852 NRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQL 916
            .|:.:||:.||.:|...||||||:||:||||||:|.|:|.|.|||..||:|.||:.|:||||:||
Mosquito   882 KRWRQKRKIWAGTGESLLLGDPMILLKAVGAAEHAHSKGVLEEFCTENGIRLKAIREIRKLRIQL 946

  Fly   917 TNEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYN 981
            |||:|.|:..:.|.|||::.|||..|.|.|||:||.|..|::|||:|.:||..|.:.|:||:|||
Mosquito   947 TNEVNANLLGMNLAVDPDMAPPTATQIRLLRQLLLIGNADQIARKLPESDIKLKTDARKLKHAYN 1011

  Fly   982 CADMEEPAFLHVSSVLRQKAPEWVIYQEAYEL--------QNGDSTKMFIRGITAIEPEWLLLYV 1038
            ...::||.|||.|||||::.||||.||||||.        :..|.||||:||||||||:||..:|
Mosquito  1012 LPMIDEPVFLHASSVLRREQPEWVCYQEAYEAIVPGVVGEEGSDKTKMFVRGITAIEPDWLPKFV 1076

  Fly  1039 PLLCNIREVREDP-APRFDKTSGKIFCHVDATFGKSGWELPLGEVEMPLSEKACCYFGMFLLDGE 1102
            |.:||..:|.|:| .|.::..:..|.|||.|||||:.||||...||||.:...|.|...|:|.|.
Mosquito  1077 PNVCNAIDVLEEPIPPAYNAATDTIECHVRATFGKTSWELPASVVEMPKNMLRCKYLLKFILQGI 1141

  Fly  1103 VCSRLADFRSKLKSTPASVIKSWSSMNNKVLRFKRALITKQIHNRQALIDQWNSDPHFLLEEYQN 1167
            |..:|..||..|.|:|.||:|.:|:...::....:.::..::.|.|...:.|.:||.|...||.:
Mosquito  1142 VFKQLKPFRKSLLSSPDSVLKLYSTAVPRIDAALKVMLANELFNAQRFHELWQADPKFFCREYAD 1206

  Fly  1168 LLYDVALSELTPLWPPVD 1185
            .|......::..|||||:
Mosquito  1207 FLPVSCHEDVAKLWPPVE 1224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	506/839 (60%)
		DEXHc_DHX37	260..439	CDD:350740	138/179 (77%)
kz	XP_312236.6	None