Protein Alignment kz and Dhx15

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_061518278.1
• Gene: Dhx15 / 1270778
• VectorBaseID: AGAMI1_008645
• Length: 745
• Species: Anopheles gambiae
• Alignment Length: 966
• Identity: 272/966 - (28%)
• Similarity: 419/966 - (43%)
• Gaps: 263/966 - (27%)

  Fly   122 KRLPTLDEYLAKKKERQAQVLAEKSSASGLRVNAIKGSKRKLLVEEEEELQAKRKNPNVISVEED 186
            :|:..:|.::.|::|       ||::|.|    |...|..||                      |
Mosquito     4 RRIEVMDPFIKKRRE-------EKAAAEG----AAGASSSKL----------------------D 35

  Fly   187 DEDSSSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPPIKKLKPEPNPPACIHQTVYVPVHRTT 251
            ...||||      .|:.::..|.....:.:..:...|.|:..:....|         |..:::
Mosquito    36 AAGSSSS------GPSSASKAAAAAAAAGSATESGGKNPLNGIAYTQN---------YYKLYK-- 83

  Fly   252 EVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYA---QHKMIGVTEP 313
                .|:.||:...:...|..::|:..:::.||||||||||:||:..|  ||   ..|.:..|:|
Mosquito    84 ----KRITLPVFEYKTDFMRLLSEHQCIVLVGETGSGKTTQIPQWCVE--YALQTSSKGVACTQP 142

  Fly   314 RRVAAIAMSKRVAHEMN-LPESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVII 377
            |||||:::::||:.||: :...||.|.||||...:|.|.:|:||||:||:|..:|.:|..|.||:
Mosquito   143 RRVAAMSVAQRVSEEMDVMLGQEVGYSIRFEDCSSPRTLLKYMTDGMLLREGMSDPMLEAYQVIL 207

  Fly   378 LDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKIPPPLLKVEAR 442
            |||||||::.||:|:|:|..::    ::.:.|||::|||||....|.:    :....||:.|..|
Mosquito   208 LDEAHERTLATDLLMGVLKEVI----RQRKDLKLVVMSATLDAGKFQQ----YFDNAPLMNVPGR 264

  Fly   443 QFPVTIHFQKRTPDDYVAEAYRKTLKIHN-KLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPT 506
            ..||.|.:......||:..|.|..::||. :..||.||:|:|||:|:.:..::::|
Mosquito   265 THPVEIFYTPEPERDYLEAAIRTVIQIHMCEEIEGDILMFLTGQEEIEEACKRVKR--------- 320

  Fly   507 KDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKL 571
                                           |.|                        ||.
Mosquito   321 -------------------------------EID------------------------NLG---- 326

  Fly   572 PGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFL 636
                        ||..:                            |..:||||.|....|.:||.
Mosquito   327 ------------PDVGE----------------------------LKCIPLYSTLPPPMQQKIFE 351

  Fly   637 PV----PDGC--RLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASAD 695
            |.    |:|.  |..|:|||:|||||||..:.:|:|.|..|.::|:....|.:.:|:..|||||.
Mosquito   352 PAPPKRPNGAIGRKVVISTNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVSPISKASAQ 416

  Fly   696 QRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPD 760
            ||||||||...|.|:|||:...|....:|.:.|:|.:..:..::||::.:|||.:|||.|..||.
Mosquito   417 QRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPA 481

  Fly   761 QVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVC 825
            ...|..|...|..|.||:    ::.:|    |.||.|::.||:.|:..|||..|.|.|.....:.
Mosquito   482 PETLMRALELLNYLAALD----DDGNL----TDLGAVMAEFPLDPQLAKMLIASCQHNCSNEILS 538

  Fly   826 LVAALSVQEVLIETGVQRDEDVAPGAN----RFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYA 886
            :.|.|||.:..:     |..::...|:    ||            ..:.||.:.||....|.:..
Mosquito   539 ITAMLSVPQCFV-----RPNEMKKAADDAKMRF------------AHVDGDHLTLLNVYHAFKQN 586

  Fly   887 G-SQGRLPEFCAANGLRQKAMSEVRKLRVQLT---NEINLNVSDVELGVDPELKPPTDAQAR--- 944
            . .||    :|..|.:..:::.....:|.||.   :...|.            :..||..:|
Mosquito   587 NEDQG----WCYDNFINYRSLKSADNVRQQLARIMDRFQLQ------------RTSTDFTSREYY 635

  Fly   945 -FLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEWVIYQ 1008
             .:|:.|:.|...:||            ...|.|: |......:...||.|:.|..| ||||||.
Mosquito   636 FNIRKALVQGFFMQVA------------HLERTKH-YQTIKDNQVVQLHPSTCLDHK-PEWVIYN 686

  Fly  1009 EAYELQNGDSTKMFIRGITAIEPEWLLLYVPL--------LCNIREVREDPAPRFD 1056
            | :.|    :||.:||.:|.::|||||...|.        ||..:...|....|.|
Mosquito   687 E-FVL----TTKNYIRTVTDVKPEWLLQIAPQYYDMNNFPLCEAKRQLELILARMD 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	248/828 (30%)
		DEXHc_DHX37	260..439	CDD:350740	76/182 (42%)
Dhx15	XP_061518278.1	None