Protein Alignment kz and Dhx57

DIOPT Version :9

• Sequence 1: NP_001284815.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001157231.1
• Gene: Dhx57 / 106794
• MGIID: 2147067
• Length: 1388
• Species: Mus musculus
• Alignment Length: 1100
• Identity: 268/1100 - (24%)
• Similarity: 467/1100 - (42%)
• Gaps: 272/1100 - (24%)

  Fly   164 LVEEEEEL-------QAKRKNP--NVISVEEDDEDSS---------------------------S 192
            |:|||.|:       |.|...|  ||..|..:...|.                           .
Mouse   414 LLEEESEIVKLLTHTQHKYSVPPVNVPPVPSETRISKPAYRKPVVPSNTFLSNQMLEGERLSELE 478

  Fly   193 SDEDDEEAPAQSAPIAIPTPVSIAPPQIAVK---PPIKKLKPEPNPPACIHQTVYVPVHRTTEVQ 254
            .|.|::|.||.   |.:.....:...:.:.|   .|.|.|..| |...|....:.....:...:.
Mouse   479 EDADEDEGPAS---IIVENESYVNLKKRSYKRYDRPAKSLFAE-NSKICRQFQMKQASRQFHAIL 539

  Fly   255 NARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIG---------V 310
            ..|..||...|.:.:::.::::.:|:::|.||.|||||:|||:.:     :.:.|         .
Mouse   540 QERQLLPAWEERETILKLLSKHQVVVISGMTGCGKTTQIPQFILD-----NSLNGPPERVANIIC 599

  Fly   311 TEPRRVAAIAMSKRVAHEMNLPESE-----VSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLL 370
            |:|||::||::::|||.|    .:|     |.|.||.|...:.|||:.:.|.||||:.:|.|..|
Mouse   600 TQPRRISAISVAERVAKE----RAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATL 660

  Fly   371 SKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKIPPP 435
            ...:.||:||.|||:..:|.|:.:|..||..|    ..|::|:|||||....|   ::.|.. .|
Mouse   661 QGVTHIIVDEVHERTEESDFLLLVLKDIVMQR----ATLQVILMSATLDAGLF---SKYFSY-CP 717

  Fly   436 LLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFP 500
            ::.:..|.|||...|.    :|.:|                 :..:|.  |:.:..:|.:::.
Mouse   718 VITIPGRAFPVDQFFL----EDALA-----------------VTRYVL--QDGSPYMRSMKQI-- 757

  Fly   501 YHHAPTKDVAKNGKVSEEEKEETI-------DDAASTVEDPKELEFDMKRVI---RNIRKSKKKF 555
               |..|..|::.:.::||.||.:       |:..|..:...:.:.|.|:::   :.:.||..|.
Mouse   758 ---AKEKLKARHNRTAQEEVEEDLRLSLHLQDEEESVKDTIPDQQLDFKQLLIRYKGVSKSVIKT 819

  Fly   556 LAQMALPKINLD----------DYK-----------LPGDDTEADMHEQPDEDDEQEGLEEDNDD 599
            ::.|...|:||:          |.|           |||......::||
Mouse   820 MSVMDFEKVNLELIEALLEWIVDGKHAYPPGAVLVFLPGLAEIKMLYEQ---------------- 868

  Fly   600 ELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYV 664
               |:..|...:.:.....:.||:|.||||:|..:|:..|.|....::|||:||||:||..:.||
Mouse   869 ---LQSNSLFNNRRSHRCVIHPLHSSLSSEEQQAVFVKPPMGVTKIIISTNIAETSITIDDVVYV 930

  Fly   665 VDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPD 729
            :|.|:.|.:.||...|:.:...|:.|:|:|.||.|||||:::|.|:.|::|..||........|:
Mouse   931 IDSGKMKEKRYDAGKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPE 995

  Fly   730 IQKKPVEDLMLQMRCMGI----------DRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTEN 784
            ||:.|:|.|.|:::.:.:          .|::     .||....|:|::.||..||||    |.:
Mouse   996 IQRVPLEQLCLRIKILEMFSTHNLQSVFSRLI-----EPPHIDSLRASKVRLRDLGAL----TPD 1051

  Fly   785 TDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAP 849
            ..|.|    ||:.::..||..|.||::.|......|...:.:.|:|:.:...:....:::|
Mouse  1052 EKLTP----LGYHLASLPVDVRIGKLMLLGSIFRCLDPALTIAASLAFKSPFVSPWDKKEE---- 1108

  Fly   850 GANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPE-------FCAANGLRQKAMS 907
             ||   :|:..:|.:.:     |.:.||.|     |.|.|....|       :|..|.|..:.:.
Mouse  1109 -AN---QKKLEFAFANS-----DYLALLCA-----YKGWQLSTKESARASYNYCRQNFLSGRTLQ 1159

  Fly   908 EVRKLRVQLTNEIN--------LNVSDVE---LGVDPEL-----KPPTDAQ-ARFLRQILLAGMG 955
            |:..|:.|.|..::        |...::|   .|.|..|     :..|:|: .:.:..:|.|.:.
Mouse  1160 EMASLKRQFTELLSDIGFVKEGLRAKEIEKRAQGGDGVLDATGEEANTNAENPKLISAVLCAALY 1224

  Fly   956 DRVA---------RKVPLADIADKEERRRLKYAYNCADMEEPAFLHV--SSV---LRQKAPEWVI 1006
            ..|.         :|.....:..:.:...||:.     .:...::|:  |||   :|.....:::
Mouse  1225 PNVVQVKTPEGKFQKTSSGVVRLQPKSAELKFV-----TKNDGYVHIHPSSVNYQVRHFDSPYLL 1284

  Fly  1007 YQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLCNIREVR-------EDPAPRFDKTSGKIF- 1063
            |.|..:     ::::|||..:.:....|:|:.....|::..|       :|...||...|.::.
Mouse  1285 YHEKIK-----TSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGAFVVSLDDGWIRFVAASHQVAE 1344

  Fly  1064 ------CHVDATFGKSGWELPLGEVEMPLSEKACCYFGMFLLDGEVCSRLADFRSKLKST 1117
                  |.:|        :|...:::.|..:...|..|         ||:.....||.:|
Mouse  1345 LVKELRCELD--------QLLQDKIKNPSMDLCSCPRG---------SRIISMIVKLITT 1387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	232/920 (25%)
		DEXDc	279..418	CDD:238005	58/152 (38%)
		P-loop_NTPase	369..>500	CDD:304359	34/130 (26%)
		HELICc	619..704	CDD:197757	38/84 (45%)
		HA2	774..859	CDD:214852	22/84 (26%)
		OB_NTP_bind	915..1039	CDD:285018	27/154 (18%)
Dhx57	NP_001157231.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..154
		UBA_DHX57	181..218	CDD:270502
		RWD	246..419	CDD:368608	3/4 (75%)
		HrpA	501..1298	CDD:224557	230/902 (25%)
		DEVH box	669..672		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810