Protein Alignment kz and dhx29

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_004910409.1
• Gene: dhx29 / 100216168
• XenbaseID: XB-GENE-995260
• Length: 1363
• Species: Xenopus tropicalis
• Alignment Length: 1060
• Identity: 282/1060 - (26%)
• Similarity: 456/1060 - (43%)
• Gaps: 233/1060 - (21%)

  Fly    70 SKKQ------RKHLQAIVDKKKKK-------EGRAQLL---GDLAAV---QIPEEELQ-QYTS-- 112
            |.||      |||.|...:...:|       :.|.:::   .|:..|   .:.|:.:| |:.:
 Frog   375 SPKQFLIDWCRKHYQKSPNPSFEKVPVGKYWKSRVKIIKSHDDVMCVCPTIVTEDSMQAQHLAAT 439

  Fly   113 -----ISQVQTVGLKRLPTLDEYLAKKKERQAQVLAE-KSSASGLRVNAIKGSKRKLLVEEEEEL 171
                 :::.|:|.....||..:...:..:.:.||..: |..::..|...|.....||.: ::.:|
 Frog   440 LALYELTKGQSVHQLLPPTYRDVWLEWSDAEKQVQEQNKMESNKPRDQFITKLLNKLKL-QQNQL 503

  Fly   172 QAKRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAIPTPVSIAPPQIAVKPPIKKLKPEPNPP 236
            ::..:||    |.||.|||..:...|||        .|.|..|.|  |.....||:.|..:....
 Frog   504 KSSGQNP----VTEDPEDSWENLACDEE--------QIETCPSTA--QTDDLEPIRNLLLKSRDS 554

  Fly   237 ACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYE-- 299
            .           :...:.|.|.:||:.|..:.::||:..:.:::|||||||||:||:||||.|
 Frog   555 I-----------KYKRLLNDREQLPVFAHRKFILETLKRHRVIVVAGETGSGKSTQVPQFLLEDL 608

  Fly   300 ---AGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNLP------ESEVSYLIRFEGNVTPATRIKFM 355
               .|......|..|:|||::|::::.||..|:...      .|...|.||.|.....|||:.:.
 Frog   609 LLNRGSPGKCNIVCTQPRRISAMSLATRVCEELGCDSGPGGRNSLCGYQIRMESRTGEATRLLYC 673

  Fly   356 TDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRV 420
            |.|:||::::.|.:|...|.||:||.|||:|.:|.|:.:|..|:   |||.. |.|::||||:..
 Frog   674 TTGILLRKLQEDSMLKNISHIIVDEVHERTVQSDFLLIILREIL---HKRSD-LHLVLMSATVDC 734

  Fly   421 SDFTENTRLFKIPPPLLKVEARQFPVTI-HFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTG 484
            ..|:.    :....|::::..|.|||.: |.:.      |.||            .|.:|
 Frog   735 EKFSS----YFTHCPIIRISGRTFPVEVFHLED------VVEA------------TGFVL----- 772

  Fly   485 QQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEF---------D 540
                                 .:|.....|..|:|:|.|:..........|..||         |
 Frog   773 ---------------------EQDSEYCQKFLEDEEEITLSVTGKGGSSTKYQEFIPALSDTGLD 816

  Fly   541 MKRVIRNIRKSKKKFLAQMALPKINLD-------------DYK---------LPGDDTEADMHEQ 583
            :.:..:......:..:..|...|||||             .|:         |||   .||:.:.
 Frog   817 LGQRYQRYSSQTRHAVLYMNPNKINLDLILELLVFLDISPQYRNVEGAVLIFLPG---LADIQQL 878

  Fly   584 PDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVS 648
            .|.                |..:......:|..|  :.|:|:|||:.|...|:..|.|.|..|::
 Frog   879 YDI----------------LSSDKRFHDRRRYKL--IALHSILSSQDQAEAFILPPAGTRKIVLA 925

  Fly   649 TNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLY 713
            ||:|||.:|||.:.:|||.||.|...|.:.:.:|:.|.|:.|||||.||.|||||:..|.|:|||
 Frog   926 TNIAETGITIPDVVFVVDAGRTKENRYHESSQMSSLVETFISKASALQRQGRAGRVRDGFCFRLY 990

  Fly   714 SSAVYNDCFEDFSQPDIQKKPVEDLMLQ-MRC-MGIDRVVHFPFPSPPDQV-------QLQAAER 769
            :...: :.|.::|.|:|.:.|:|:|.|. |:| :|          ||.|.:       |||....
 Frog   991 TRERF-EGFMEYSVPEILRVPLEELCLHIMKCDLG----------SPEDFLSKALDPPQLQVISN 1044

  Fly   770 RLIVL---GALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALS 831
            .:.:|   ||.|:       :.|.:|.||..::..||..:.||||........|.....|.|.::
 Frog  1045 AMNLLRKIGACEL-------IQPRLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDAVATLAATMT 1102

  Fly   832 VQEVLIETGVQRDE-DVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPE- 894
            .:...:....::|. |:|         :.|.|.:.:     |.:.:.||....:...|.|...|
 Frog  1103 EKSPFVTPIGEKDRADLA---------KSSMAVANS-----DHLTIFRAYLGWKAIRSDGYAAEM 1153

  Fly   895 -FCAANGLRQKAMSEVRKLRVQLTNEINLNVSDVELGVDP-----ELKPPTDAQARFLRQILLAG 953
             :|..|.|.:||:..:..::.:|...:.....:....|:|     .:|..:..:...|:.||.||
 Frog  1154 SYCRKNFLNRKALLTIEDVKQELIRLVRAAGFECPRFVEPNGLSDNMKALSAEETSLLKAILTAG 1218

  Fly   954 MGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQ-KAPEWVIYQEAYELQNGD 1017
            :.|.|. |:...:..|..|    |.|......:..|.:|.|||.|. :...|::|||..:.
 Frog  1219 LYDNVG-KILFTNSVDITE----KLACMVETAQGKAQVHPSSVNRDLQTYGWLLYQEKIKY---- 1274

  Fly  1018 STKMFIRGITAIEPEWLLLY 1037
             :|:|:|..|.|.|..:||:
 Frog  1275 -SKVFLRESTLITPFPVLLF 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	235/842 (28%)
		DEXHc_DHX37	260..439	CDD:350740	69/189 (37%)
dhx29	XP_004910409.1	HrpA	565..>1184	CDD:441249	202/723 (28%)
		OB_NTP_bind	1211..1297	CDD:400182	30/93 (32%)