Protein Alignment kz and dhx57

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001163976.1
• Gene: dhx57 / 100124795
• XenbaseID: XB-GENE-976876
• Length: 1180
• Species: Xenopus tropicalis
• Alignment Length: 957
• Identity: 249/957 - (26%)
• Similarity: 419/957 - (43%)
• Gaps: 228/957 - (23%)

  Fly    72 KQRKHLQAIVDKKKKKEGRAQLLGDLAAVQIPEEE-------LQQYTSISQVQTVGLKRLPTLDE 129
            |...||.|        .|....|.:| .|:.|::.       |..:.|:::..::|.:.  .:.|
 Frog   337 KDESHLCA--------NGNNNCLYEL-EVRFPKDNKYPYQAPLLAFYSVNENLSMGCRL--HITE 390

  Fly   130 YLAKKKERQAQVLAEKSSASGLRVNAIKGSKRKLLVEEEEEL----------------------Q 172
            ||.:|    |..:|:.|..:...:.:        .:|:|:|:                      .
 Frog   391 YLYEK----ALNIAQTSDPAVYTLVS--------CLEDEDEIVKLLANTHHKYSIPPPLLLTATS 443

  Fly   173 AKRKNPNVISVEE-------------------------DDEDSSSSDEDD-EEAPAQSAPIAIPT 211
            ..|||| ||::.:                         |....:.:|||. ::..::|..:...:
 Frog   444 DTRKNP-VITINKPVAPDKPSLLSYPSGARKGQKPIKMDISKPNDTDEDSLDDLESESVLVENES 507

  Fly   212 PVSIAPPQIAVKPPI--KKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETIN 274
            ..::...| |.|...  .|.....|...|.|............:...|.:||...::.|::|.::
 Frog   508 YANLKKKQ-AKKYSFNSNKAVAAENAKICKHYRAKKTTRNYQSMLEERQKLPAWQKQDQILELLS 571

  Fly   275 ENPIVIVAGETGSGKTTQLPQFLYEA---GYAQH-KMIGVTEPRRVAAIAMSKRVAHEMNLPESE 335
            :..:::|:|.||.|||||:|||:.:|   |...| ..|..|:|||::||::::|||.|    .:|
 Frog   572 KYQVLVVSGMTGCGKTTQIPQFILDASLKGPPSHVSNIICTQPRRISAISVAERVAQE----RAE 632

  Fly   336 -----VSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLL 395
                 |.|.||.|...:.|||:.:.|.||||:.:|.|..|...:.:::||.|||:..:|.|:.:|
 Frog   633 RVGISVGYQIRLESVKSAATRLLYCTTGVLLRRLEGDTTLQNVTHVVVDEVHERTEESDFLLLVL 697

  Fly   396 SRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKI---PPPLLKVEARQFPVTIHFQKRTPDD 457
            ..::.||    ..||:|:|||||       |..||..   ..|:|.:..|.|||..:|
 Frog   698 KDVMVLR----PDLKIILMSATL-------NAELFSCYFQDCPVLHIPGRTFPVDQYF------- 744

  Fly   458 YVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHA----PTKDVAKNGKVSE- 517
             :.:|..||..:   |.:|.                      ||..:    |..|.|:..|.:.
 Frog   745 -LEDAIAKTRYV---LEDGS----------------------PYQRSSKQLPGPDSARGKKGNSY 783

  Fly   518 ----EEKEETIDDAASTVEDPK-------ELEFDMKRV---IRNIRKSKKKFLAQMALPKINLD- 567
                :|.|:.| .::..::|.|       :.:.::|.:   ...|.||..|.|:.|.|.|||||
 Frog   784 NELLDELEQQI-SSSLRIQDSKIVKDSVPDQQLNVKELSVRYNGISKSVIKTLSSMDLDKINLDL 847

  Fly   568 -----DYKLPGDDTEADMHEQPDED--DEQEGLEEDND--DELGLEDESGMGSGQRQPLWVL-PL 622
                 ::.:.||      |..|...  ....||.|...  |:|   ..:.:.:.:|....|: ||
 Frog   848 IEALLEWIVNGD------HSYPPGAVLVFLPGLAEIKTLYDQL---QSNALFNNRRSKRCVIYPL 903

  Fly   623 YSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVT 687
            :|.|||::|..:||..|.|....::|||:||||:||..:.||:|.|:.:.:.||....:.:...|
 Frog   904 HSSLSSDEQQSVFLKPPPGVTKIIISTNIAETSITIDDVVYVIDSGKMREKRYDPGKSMESLEDT 968

  Fly   688 YTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCM------G 746
            :.|:|:|.||.|||||:::|.|:.|::|..|.....|...|:||:.|:|.|.|:::.:      .
 Frog   969 WVSRANAMQRKGRAGRVASGVCFHLFTSHHYQYQLLDQQLPEIQRIPLEQLCLRIKILEMFSECR 1033

  Fly   747 IDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKML 811
            :| :|......||....|.|::.||..||||    |:...|.|    ||:.::..||..|.||::
 Frog  1034 LD-LVFARLIEPPRMESLHASKIRLQDLGAL----TKEEKLTP----LGYHLASLPVDVRIGKLM 1089

  Fly   812 ALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVL 876
            ........|...:.:.|:|:.:...:....:::|     ||   :|:|.:|.:.:     |.:.|
 Frog  1090 LFGAIFRCLDPALTIAASLAFKSPFVCPWDKKEE-----AN---KKKQEFATANS-----DHLAL 1141

  Fly   877 LRAVGA----------AEYAGSQGRLPEFCAANGLRQKAMSEVRKLR 913
            |:|..|          |.|        ::|..|.|..:.:.|:..|:
 Frog  1142 LQAYQAWSSVIKESSRAAY--------QYCRDNFLSVRVLQEIASLK 1180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	208/712 (29%)
		DEXHc_DHX37	260..439	CDD:350740	70/190 (37%)
dhx57	NP_001163976.1	UBA_DHX57	185..222	CDD:270502
		RWD_DHX57	246..424	CDD:467661	22/109 (20%)
		zf-CCCH_4	308..329	CDD:465626
		HrpA	557..>1109	CDD:441249	189/618 (31%)