|
Fly 1 MGSQTLEILRQGVWASLTGGYFYDPHQGVFCNVVHLYLWLYLLCSPFVAYLIFLQYFPSTWLTWC 65
||||||:|||||||||:|||::|||||..|.|.:||||||.|||.||..|:. .|.|.:...
Zfish 1 MGSQTLQILRQGVWASVTGGWYYDPHQNTFVNALHLYLWLLLLCLPFTLYMA----LPPTMVIVG 61
Fly 66 LYCVITSLTILMVKLANLALHRLYDRAQTM------SEGNLKGQFVKVTKE-TEPRHDDEGGIEM 123
:||.:.:...:::|..|..||...|..:.: ||| :||..:..:| |..|.:|..|
Zfish 62 IYCGVIAGMFVLLKAVNYRLHTALDEGEVVELRAKGSEG--RGQGAERQREGTSTRQEDSNG--- 121
Fly 124 KVIRPGGSRISGEQAINEASEENSIMSIDNVNSIIDLKVDVHRKNSSESIELMFYAPSMLSGGSQ 188
||
Zfish 122 ----PG----------------------------------------------------------- 123
Fly 189 QDQQSLAGSASVSKSIRSTGPGGNSSTSAAAQADMFNKYLTVYPEVVEAAGSSAGSADGGSSGGD 253
.|||....|..|: .|......||..|..|..|...
Zfish 124 -------------------DPGGGIEMSDFAR-----------DETPPVDCSSRNSYVGMDSSHQ 158
Fly 254 SRSGAAVSTLGHTGAGTAPAQHVRTGHLSRKCSEVFSRRHRRRLERQSSLDTAAAAANSNAENK- 317
..|..|..|...||.|.||. |.:.:.|.|.::::
Zfish 159 ITSHGASVTNKRTGVGKAPD------------------------------DISLSFAQSCSQDQD 193
Fly 318 LMRNQSDTIATAAPSFLHSQPTNKARGQTNPRQHFITSAPSTGIGGGDAPTSSTAVVVIAPASNS 382
||.:.......:..||...||: |:..|....|.|. |.|.|
Zfish 194 LMSDPKMFCLVSNDSFASMQPS------TSLAQDLYGSTPH-------------------PFSQS 233
Fly 383 LVNPGRSSRLQRHRSSETHDERLKHQS---RGGLFQPILQLPHHSAASSIGALAVLGGGGNVAAN 444
| ....:.:..|.| ||.:..:.:| || ||..| ||.|: |..
Zfish 234 L--SSCDTEITAHLS--THSQSFRKESSRPRG--------LPRTS--SSAGS----------AFP 274
Fly 445 DVEDMELGLVRNAGSGGVADAC----SRALQSWILDPFPDGYLEDDSYTKSDLGIEQPHQPTFRT 505
|....|..|......||:...| ||:.:: .:...:.||.|.|..|.|..
Zfish 275 DPSLPEFSLYPPPRRGGLDPVCEMDSSRSQRA------TESSEQADSGTPSTSGTECT------- 326
Fly 506 QHRHHHHHHHLHHHLGGAIIRKDPTSTMSALQLAAVTQPGTGGSVTGGGGAAGGGGSAAGMKRRR 570
.:|...|..|..::.|: ||.|..||.||| |:.|
Zfish 327 -----RYHLKEHRRLSRSVSRE-----------------------TGEGECAGEGGS--GLYR-- 359
Fly 571 HSNATSYKHGSSQSNKSSLVGGGGSRGPSGEAGTSGGAGGTGGVRRIKSAALEVLCPQPSVSNLS 635
..|..||...||| .|| .|:.:||
Zfish 360 ------------------------------SEGVQGGCERTGG----HSA--------ESLRSLS 382
Fly 636 PHPNSVEAISGQQQMRNPLPPPSKSLVRNQHLNLYPTQGYGDGTPSAGGGGPGNSSTCSSLFFGS 700
... ||. |:.|..||.. ..:||.||| .
Zfish 383 TRS------SGS------------------------TESYCSGTDR------DTNSTLSSL---H 408
Fly 701 SSACGSTTALIEPPVYPIVEHSDEKTAHEEHGD-DCLGIGQGNADDDDEVDDVPIRRRTRALGCS 764
|....|| .|..::..|.::..:..|.| ....:..|.|:.:...:::.|:..|
Zfish 409 SEQTSST------HVESLLSLSGDEKVNAGHADARNSNVASGEANKNPHANELAIKLPT------ 461
Fly 765 QTHYSVESDVGGFLADEVGADEDVFKDFDDNLEHILSELQQTHNQLDDVLKTHDLHHHSHLHHHK 829
||..:.:.||.||.
Zfish 462 ----------------------------DDPPKSLNSESQQG----------------------- 475
Fly 830 AASVEGAGPSGGSVAVGVSAGNDDEDEETED---------NNTGSRSPLLNDRNRQPATLREIQA 885
||...:....:..||||:..::.|.:. :...|.|.......|:....|....
Zfish 476 ----EGTVEATSRTSADVSAGHQHQETEPDKVRPKTVNLVHRAASSSAATRSGRRRNGKQRASSF 536
Fly 886 DKQLRQELSHQSGAVIPAPNPPVPIRSEADSGCPSSDCEQVSASSKDQLLSGIELELQQYQIL-Q 949
|....:| :..|..:..|...|.::.|.| |||..::|.:| .|.|..:|........ .
Zfish 537 DASRHRE--YICGRGMAKPRSAVFMKGEED----SSDQSELSCAS--SLHSTHQLSTDSSSSTPH 593
Fly 950 RCQLDEEQPCTSKMAAKSLGAIPKVVKYREVDELRRRRRGGSPADAAEAGNEFALVKQTKQASRN 1014
.|...||:...| :.||..|......|.:|.:..:.:.:| .::|||.
Zfish 594 SCPSPEERRRPS-LRAKMHGMPTSGQKVKEKERQKDKEKG------------------KRRASRR 639
Fly 1015 SSSSNS--THS--ISLTDSLTA---DIHKMLWLMHGGAVDDRGRPITGTSAD-----GTPIPASS 1067
:.|:.| ||: :||..|.|| |.| |.|| ....||:|.:.:| |..:.|:|
Zfish 640 TPSTGSAKTHARVLSLDSSTTACLNDPH------HLGA-PASSRPLTTSKSDLEAKEGEVLDAAS 697
Fly 1068 SLVPPNMSNAHFQFYQDAIQALQGTHPTSGSSVEHMTNIELARDKLRLDAKLMCEQLVAAAEANS 1132
.| ...|.:|.:|. :|:.|.....|...| .|.|.|
Zfish 698 LL-------------------------GRASQLESVTR---SRNSLPCPISLSHTQ---DAMAGS 731
Fly 1133 GVRGN----TLATQQMT--QQQVGMLMRGGSSSRHPSS---APFSVQGLI--------NVIRSER 1180
...|| |...::.| :|.|......||:|..|:| :|.|:|..: :.:|.:.
Zfish 732 RAPGNDDTVTFRRERSTFRRQAVRRRHNAGSNSTPPASLIGSPLSLQEALSQVSQASGSQVRGQP 796
Fly 1181 PAARSQLDALQQLSDAAAALAANAS---EAASVSASGAGGGASSGGGGVLSA---------LGLA 1233
....||:.. ||.:|:.|..|.| |.....||..|..:.....|.|:. :.|.
Zfish 797 SRTPSQVTV---LSTSASLLVRNGSAQLEGCPDKASTVGVASLQDEFGKLTPPLYEVGGCDMSLV 858
Fly 1234 N-----------------HPSNQIS--------------QISQLSQMSQPML---NVDG------ 1258
| |.|:..| ::::|..|...:| :|||
Zfish 859 NFEPATRRASNNLWETDSHLSSSTSVRFYPHDLFSFPQMRLNRLLSMDPELLEQHDVDGSPDLQE 923
Fly 1259 ---------HFAPYCDYWRPACLLSATEKPAAPKSFYKY---RFKWCGQEHEFKIAMDRLELLAL 1311
|..|:.. .|...| |.:|:: .:.|.| :..|||.||||
Zfish 924 APHGTQDSTHNHPHTH-----ALAHKT------KQYYRFWLLPYLWVG------LHFDRLTLLAL 971
Fly 1312 FDRDLHWMHVLLASLLCTLVACLGAAILQHDHYKDLCALLFCAVIAGAQYSLVKSVQPDAASPVH 1376
|||:...:..||:..|..|||.||:.:|.|..:.|:....||.|||..||||:||||||::||.|
Zfish 972 FDRNREVLENLLSVALAVLVAFLGSVLLVHGFFTDIWVFQFCLVIASCQYSLLKSVQPDSSSPRH 1036
Fly 1377 GFNKTVAYSRAIYFCLAGGMLLLLKRLDTDYG--ERTPDPVVFFGMRYSPADVVALLLQALYILL 1439
|.|:.:||||.:||||..|::.|| .|| ..:.:.|..:|:..:.:.:::.....|.:..
Zfish 1037 GHNRIIAYSRPVYFCLCCGLIWLL-----HYGSVNCSTNAVSLYGVALTSSVLLSQARDLLIVFT 1096
Fly 1440 LCFPIIFSVGLCPQINTFLMYLLEQIDMHVFGGNAASSLLGSFLCVVRSVLAVMLLYGPLYGALD 1504
||||:||.:||.||||||:||||||:|:|.|||||.:|||.:...|:||::.:.:|||..||||.
Zfish 1097 LCFPVIFFIGLLPQINTFVMYLLEQLDIHFFGGNACTSLLSALYSVLRSIVTIAMLYGFCYGALK 1161
Fly 1505 EQRGTQYI--LFSIFCAMLVPLGYHLSRCASDFSHLWRLIKTCIVSTYRDDEDED-LSQMQHIAT 1566
:....|:| |||:||.:||.:.|||||.:||.|.|..|:::.:....:|...|| ||::|
Zfish 1162 DSWDPQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLISLVQSKVFPNVKDKNPEDPLSEVQ---- 1222
Fly 1567 GTVTGSGTANSTALQLTTSTPKQHRQTDVKTEHEQIELSSLEKLTVNEEHHEKDHGADDQLETDQ 1631
Zfish 1223 ----------------------------------------------------------------- 1222
Fly 1632 DLPLQQKHSKSKTSSLGSSQQTLGKTISSSKRAITASSSCTSIGTGEPAVEAGALTEEAVEGEEQ 1696
Zfish 1223 ----------------------------------------------------------------- 1222
Fly 1697 RRNTLAGEVGSKHELAENYDQAAKIDECEDKISSSSATNPGDMSTLTAGAGTATTDATPACLEAD 1761
Zfish 1223 ----------------------------------------------------------------- 1222
Fly 1762 PDAEAEAPADEKQHQGILGTGTGTGTGTTEASENGSGGGANGNTNSNGTGNDLPDPLPRKLQATV 1826
||||.||:::|
Zfish 1223 ------------------------------------------------------DPLPDKLRSSV 1233
Fly 1827 TTRLKNDLVVMTLLAVSVLGLHCSTVFTALQPDLNVVLYSFIGVLGLLLHYIVPQMRKHMPWLCF 1891
..||::|::|..::||....:|.||||.||||.|:.|||..:|.:|||.||::|||||.:||.||
Zfish 1234 NERLQSDVIVCVVIAVLYFAIHVSTVFIALQPFLSYVLYGLVGSVGLLTHYLLPQMRKQLPWYCF 1298
Fly 1892 SRPLLRQREFGQFEVLNAPKIMWFEKLYIYLSVLERNVLFPLLAISSLTADSQLIVA--KFGLPW 1954
|.|||:.||:.|||:..|..:||||:.:::|..:|:|:|:||:.::.|:..:|.:.. |.....
Zfish 1299 SHPLLKTREYYQFEIRGAAHVMWFERTHVWLLFVEKNILYPLIVLNELSGSAQELAGPKKLNTEI 1363
Fly 1955 GTLIVAICALKFVRNAYSDPTNQYLIIIFTVLLFRIDFAMATETFIIDYFFVSLAFRKCCDFLLK 2019
|.|::.|..||.:|:::|.||.||:.::||||.|..|:...:||.::|.|.:|:.|.|..:...|
Zfish 1364 GALVITIAGLKLLRSSFSSPTYQYVTVLFTVLFFTFDYRQFSETMLLDLFIMSIIFSKLWELFYK 1428
Fly 2020 LQFIVTYIAPWQITWGSAFHAFAQPFSVPHSAMLFLQAAISAVLSTPLNPFLGSAIFLTSYVRPI 2084
|:|:.|||||||||||||||||||||:||||||||:||.:|||.|||||||||||||::|||||:
Zfish 1429 LKFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAIVSAVFSTPLNPFLGSAIFISSYVRPV 1493
Fly 2085 KFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLTRSLQHSLCGDLLMGRWGNVNQG 2149
:||||:|||:|:|||||||:|||:|:.|:|||||||||||||||||||||||||.:|||||.:.|
Zfish 1494 RFWEREYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLQLGRWGNYSTG 1558
Fly 2150 DCFVLASDDLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREVEAITEDVEDNDGCCCCDPGHLP 2214
|||:||||.||.|||::|:||||.|||:||||||||||||||||||||.||:::.||||:|||||
Zfish 1559 DCFILASDYLNALVHLVEIGNGLITFQLRGLEFRGTYCQQREVEAITEGVEEDESCCCCEPGHLP 1623
Fly 2215 QLLSANAMFSTRWLAWQVVAAQYVIEGYSISDNLASATLQVFEYRKVLITYYIKSIIYYVVKNPK 2279
.|||.||.|..|||||:|:..:|.:|||||:||.|::.||||:.|::|.|||:|.|||||:.:||
Zfish 1624 HLLSFNAAFGQRWLAWEVLVTKYALEGYSITDNSAASMLQVFDLRRILTTYYVKGIIYYVIASPK 1688
Fly 2280 LEQWLASGPIQDALQHTLSRQFVDLDPIFNFNLDEDFDFRAVGITRSSFCYVYLKWINYCVDMRR 2344
||:|||:..:.:.|:....|.:|||||.||.|:|||:|.|..||:|.|||.|||.||.||
Zfish 1689 LEEWLANEGLLEGLKSCGERNYVDLDPTFNPNIDEDYDHRLAGISRDSFCSVYLSWIQYC----- 1748
Fly 2345 DANSMGGAPPAQAPAAAGGASSAPATAGVAPPAPVTPAHNDSKSTPNLSAHGGQAGPSSGQSKSQ 2409
Zfish 1749 ----------------------------------------------------------------- 1748
Fly 2410 SQQQLRRPQKSVAQETSVGGGGVVVGGTTVPGTGGVTGGGGDPQLSSSHSFANISRQTSESAPGL 2474
Zfish 1749 ----------------------------------------------------------------- 1748
Fly 2475 GGYVAYMDQNVFVKLAKSSTTTGAGAGAPTSRKESQEKPALRLKLASVGKDAPLVSLCLALGLLA 2539
.||: ||| ....||:.||.||..|.:|.
Zfish 1749 -----------------------------NSRR---EKP------LDSEKDSLLVLLCYGLCVLG 1775
Fly 2540 RRSLATASHSALTGVEFFLHGLHALFKGDFRITSPRDEWVFADMELLHSVVAPAVKMALKLQQDH 2604
||:|.||||...:.:|.||:||||||||||||:|.||||:|.|||||..||.|.::|:|||.|||
Zfish 1776 RRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFTDMELLRKVVVPGIRMSLKLHQDH 1840
Fly 2605 ITNPDEFLDPHALYDAIDNCSNELVISHEADPVWRSAVLRGAPNLLALRHVMEDGSDEYRIIRLT 2669
.|:|||:.:...|::||.:....|||:||.||.||:|||..:|:|||||||:::|::||:||.|.
Zfish 1841 FTSPDEYEESSVLFEAISSHEQTLVIAHEGDPAWRNAVLSNSPSLLALRHVLDEGTNEYKIIMLN 1905
Fly 2670 KRCLSFRVIKLNRECVRGLWAGQQQELIYLRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYV 2734
:|.|||||||:|:||||||||||||||::||||||||||||||||||||:|||||||||||||||
Zfish 1906 RRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYV 1970
Fly 2735 SPLTTSYADTNAQLCEVIGGAITLDTIRHTVLGWWHRIRERCRQGCSSGSALEPHPGSGPVQLGA 2799
|||||||.:|:.||..::||.|::..||:.::..|||:|:.|..||:||..:|.
Zfish 1971 SPLTTSYCNTHPQLGHILGGPISIANIRNFIVNTWHRLRKGCGAGCNSGGNVED----------- 2024
Fly 2800 CNFGSGGSVVGAASTATGVGASTGSGLGVAAPGTAGSTGGESGDLAPVFISAPLYNTLTVNSYYS 2864
|:.| |.|.|| |.:|::|..:.| |.:|
Zfish 2025 CDAG---------------GLSCGS-------GNSGNSGTGASD-----------------SQHS 2050
Fly 2865 VRPGNVPGGP------IPGNLGGNYVSDSLAVVRGGLAVMPVKPTSTTLIAGLLNRERDETSGSG 2923
.|| .|.:||.:..|.| |:.||.
Zfish 2051 -------SGPTALHAYTPHSLGTSQSSQS---VQSGLV--------------------------- 2078
Fly 2924 IMGAGASGPTRATSSGGVRSRRPEVGSSRGRDHERRATLPIASGGAGGEPGKDLTAPQTQVEHEP 2988
...|.||: |.|:......|..|....|.:: .|.||.:..::.|..:...|
Zfish 2079 -----RQSPARAS----VVSQSSSYRHSSSRQSSLRTSV------TGLEPCRRSSSSQLSLRTLP 2128
Fly 2989 SPRSTKLSSSSGSLGLGMGVGLGNIITTPGDYPRKTKGPICLTAVDTGTSSSAAEGKP------- 3046
:....:|.::|. |..| :..|| :||.:|...|
Zfish 2129 TSLQLRLGTNSS-------------IANP-----EPPGP---------SSSLSAHSIPPCKRHAH 2166
Fly 3047 --AG----SGTVAGTGVG-------------------GVIRKPRIEIFKKVIIVDDTGIYDCLDI 3086
|| ...|.||.:. ..:| |.:|..:|.||| :...||:
Zfish 2167 TLAGLLGNEALVLGTDIHPHPHHHLHYIHHHHHNPSLSCLR--RDDISYRVQIVD---VSQVLDV 2226
Fly 3087 ID-----AVVWPTERMRNNGGRLSWKDWEPSAGMVGHVVHCWTPNHKDIRFRSHVNRYVYLVEIG 3146
.: .:|||.|.||...||..|::|.|..||.|||||.|.|..:|...|||:::.:.||::.
Zfish 2227 TNHPKRKELVWPDESMRLRSGRNFWREWTPLEGMEGHVVHRWVPCSRDPVSRSHIDKTILLVQVD 2291
Fly 3147 DHYVPVEELGLRE 3159
|..||:.|.|:.|
Zfish 2292 DKLVPIIETGVIE 2304
| 
