|
Fly 1 MGSQTLEILRQGVWASLTGGYFYDPHQGVFCNVVHLYLWLYLLCSPFVAYLIFLQYFPSTWLTWC 65
||||||:||||||.||||||::||.||.||||.||||:||:||..||:.|: |||:|...|.
Mosquito 1 MGSQTLKILRQGVLASLTGGWYYDVHQNVFCNAVHLYIWLFLLFLPFIIYM----YFPTTVAVWS 61
Fly 66 LYCVITSLTILMVKLANLALHRLYDRAQTMSEGNLK---GQFVKVTKETEP------RHDDEGGI 121
:|||:.::.|...|:.|:||||:||||:|:||.||| ....||.:|... ..|||.||
Mosquito 62 VYCVLIAIIITFFKMVNVALHRMYDRARTLSETNLKKPGSASSKVPREAGAGIGIGGSGDDEPGI 126
Fly 122 EMKVIRPG-----------GSRISGEQAINEASEENSIMSID---NVNSIIDLKVDVHRKNSSES 172
||:::..| .||.|.|...:|.|..||.:||| .|.|.|||||||||||||||
Mosquito 127 EMQILGTGEVAGSTPPANMSSRTSVEHHSDENSYANSAISIDYQEQVTSTIDLKVDVHRKNSSES 191
Fly 173 IELMFYAPSMLSGGSQQDQQSLAGSASVSKSIRSTGPGGNSSTSAAAQADMFNKYLTVYPEVVEA 237
:.|.||||. |..|:..|.| .
Mosquito 192 ------SDSGLSGGG--------------------GAAGSGPTGA-------------------G 211
Fly 238 AGSSAGSADGGSSGGDSRSGAAVSTLGHTGAGTAPAQH--------VRTG-----HLSRKCSEVF 289
.|..||.|.||...|.....||.|.........|.|.: ||.| |.:..||
Mosquito 212 TGGVAGGATGGGLVGAVVPSAACSDACFRSDRIAEANNETPFGAPVVRYGGPVKTHTAEVCS--- 273
Fly 290 SRRHRRRLERQSSLDTAAAAANSNAENKLMRNQSDTIATAAPSFLHSQPTNKARGQTNPRQHFIT 354
:..|:|.|...|. |..:.........::.|...| :..||..
Mosquito 274 TGTHKRSLSTPSQ-DRFSELVLETVMREMTREFGD-LPLAANG---------------------- 314
Fly 355 SAPSTGIGGGDAPTSSTAVVVIAPASNSLVNPGRSSRLQRHRSSETHDERLKHQSRGGLFQPILQ 419
:||.|||.:..|..|| |.:.|:....::.|:||:......:|..:. |
Mosquito 315 ---ATGAGGGGSGKSGEAV-----AGSRLLGAQSNASLRRHQYKSKRKQRFMNS----------Q 361
Fly 420 LPHHSAASSIGALAVLGGGGNVAANDVE---------DMELGLVRN-----AGSGGVA-DACSRA 469
|....:..|... .|.||.|:::. :|..|..|| .|:||.: ||....
Mosquito 362 LQRQISLDSEKL-----NGSNVFADELAGCDQGKLGGEMPDGGARNRRRTTGGAGGSSTDAGGVG 421
Fly 470 LQSWILDPFPDGYLE-------DDSYTKSDLGIEQPHQPTFRTQHRHHHHHHHL----------- 516
|:|.|: ||...|| :|....|| ..|.|||||||:
Mosquito 422 ---------PEGGLQLQRHLSSDDQNNKS-VGSLFHHQ----LHHHHHHHHHHMLALQNLDPDLY 472
Fly 517 --HHHLGGAI--------------------------IRKDPTSTMSALQLAAVTQPGTG--GSVT 551
|::...|: ||:|.:||||||||..:....:| |:.:
Mosquito 473 MDHNYTKSAVQLAIADTGSGNDASGKITYLLHQTTPIRRDSSSTMSALQLPTIASSSSGPVGASS 537
Fly 552 GGGGAAGGGGSAAGM-----------------KRRRHSNATSYKHGSSQSNKSSLVGGGGSRGPS 599
.|||.:|.|.|.||: |||||||.. ::..||.|:..|.
Mosquito 538 VGGGVSGDGVSTAGLGAGGDRAVSRGGNNASGKRRRHSNTA-----------ANTAGGNGAGRPL 591
Fly 600 GEAGTSGGAGGTGGVRRIKSAALEVLCPQPSVSNLSP-HPNSVEAISGQQQMRNP----LPPPSK 659
..:.|| ||||||||||. |...|:.||:| ||||||.|.| |.:||| ||||||
Mosquito 592 PRSLTS--------VRRIKSAALET-CSPASIPNLTPTHPNSVEVIGG-QTLRNPRHTVLPPPSK 646
Fly 660 SLVRNQHLNLYPTQGYG-DGT----PSAGGGGPGNSST-----CSSLFFGSSSACGSTTALIEPP 714
.|.||.:|||:.....| .|| ...|||..|.||: |.|.....|...|:|.|..: |
Mosquito 647 CLSRNPYLNLFTKSNEGSSGTGLVDVCGGGGVAGGSSSFAGAGCDSAAAFESVLPGATNAGSD-P 710
Fly 715 VYPIVEHSDEKT------------AHEE----------HGDDCLGI----------GQGNADDDD 747
||||.|.|||.| |.:| |.|...|: |.|..::||
Mosquito 711 VYPIAEQSDESTPVKSAAGTGRVMARDESTPPVQRFDLHSDSEDGLEDDDEDEEDEGDGEEEEDD 775
Fly 748 EVDDV-----------PIR-RRTRALG---CSQTHYSVESDVGGFL--ADEVGADEDVFKDFDD- 794
|.||| |.| .|:|..| ..:::|:.|. | .|.:|..|:.....|.
Mosquito 776 EDDDVDEEEENIEQEAPGREERSRQEGEELRGESYYAAEE-----LKKPDRIGDSEEDLTLHDQL 835
Fly 795 -NLEHILSELQQTHNQ-----LDDVLKTHDLHHHSHLHHHKAASVEG------AGPSGGSVAVGV 847
.|.|...:.||.|.. :||.|: .||.||. :||.
Mosquito 836 RRLHHQQQQQQQQHQPRMSEGVDDSLE-------------DAAGVESDMEHPDSGPQ-------- 879
Fly 848 SAGNDDEDEETEDNNTGSRSPLLNDRNRQPATLREIQADKQLRQELSHQSGAVIP---------- 902
:.|.|.|| |.|||||||..|..:..:.:::.| ..:.:..:....|::|
Mosquito 880 ---STDSDTET---NAGSRSPLLEPRTHRTNSEQQVGA-ATIVEAKNAACCAIVPPKLIGSEVKK 937
Fly 903 -APNPPV------------------PIRSEADSGC-PSSDCEQVSASSKDQLLS----------G 937
:.:|.: |:::..::|| .|||.||.||||||.|:: |
Mosquito 938 TSSSPTISCSDSSALHLHHHHMLRSPMKAFEETGCLSSSDWEQASASSKDLLIAKDGAVAKEGHG 1002
Fly 938 IELELQQYQILQRCQLDEEQPCTSKMAAK-----------------------------------S 967
....|: :.:...:.|.:.|.:|..|:| :
Mosquito 1003 ASGALK--KAVATSESDPQIPGSSGAASKTKTNDEATAGCSAVTDTANGSTLSVAQLQQQQQPRN 1065
Fly 968 LGAIPKV--------VKYREVDELRRRRRGGSPADAAEAGNEFALVKQTKQASRNSSSSNSTHSI 1024
||||||. |:...|:| ..|:.:::..|. .:.|...|.|...:|.:...|
Mosquito 1066 LGAIPKTSPPGRSASVRRLSVEE-------NYPSTSSKIYNR--SLSQRLLAERIPENSTAAPLI 1121
Fly 1025 SLTDSLTADIHKMLWLMHGGAVDDRGRPITGTSADGTPIPASSSLVPPNMSNAHFQFYQ------ 1083
:.. :..:|:......:.|.:.....:..:.|.....|:||. |....|...:..:
Mosquito 1122 TFL-NYRSDVPIPPIYLPGNSALSEQQTASFTFRRPAPLPAR----PYRQLNCRLRMLKSDGGSE 1181
Fly 1084 ----DAIQALQGTHPTSGSSVEHMTNIELARDKLRLDAKLMCEQLVAAAEANSGVRGNTLATQQM 1144
.:..|..|...::|::.........|.:..|.|....|...:.|.|:.. .|..:|||
Mosquito 1182 GGAGSSSLAQSGVSSSAGAAASSTGTAAAAGEYWRDDDNNNCNYCLDALESPQ-TRLQSLAT--- 1242
Fly 1145 TQQQVGMLMRGGSSSRHPSSA----------------PFS----------VQGLINVIRSERPAA 1183
.|....|||.:.:|:.| |.: ::...||::....|.
Mosquito 1243 ----AGAAAGGGSFAGYPAGARSICHDALMPGTVGEVPLNFYVTDDSDRWLRCAANVLKERFGAF 1303
Fly 1184 RSQLDALQQL----------SDAAAALAANASEAASVSASGAGG--GASSGG--GGVLSALG--L 1232
...|.:...| |.:..:.:..:.....:.:.|.|| |.:||| ||.:|:.| .
Mosquito 1304 NHHLHSHHHLHHHHHHHRTISISGPSTSGTSGVIGGLGSGGVGGSSGLASGGPTGGTISSAGDDF 1368
Fly 1233 ANHPSNQISQISQLS-------QMSQPMLNVDGHFAPYCDYWRPACLLSATEKPAAPKSFYKYRF 1290
.....|..|.|:..: .:|:....:| ..|..:...:.....||.:||...
Mosquito 1369 NTASINSGSGIADKTIVASTDCSLSRAQSTID---------VVPHSMFGESGPKVRPKRYYKLSL 1424
Fly 1291 KW-CGQEHEFKIAMDRLELLALFDRDLHWMHVLLASLLCTLVACLGAAILQHDHYKDLCALLFCA 1354
:: |.:|| ..|:|:||:||||||||..|:.|:||..|||||:.||:.:|....|:||.|.:||.
Mosquito 1425 RFLCFREH-LNISMNRLQLLALFDRDTSWVQVVLAIALCTLVSLLGSLVLFQKFYEDLYAFIFCF 1488
Fly 1355 VIAGAQYSLVKSVQPDAASPVHGFNKTVAYSRAIYFCLAGGMLL----LLKRLDTDYGERTPDPV 1415
||||:||||:||||||||||:|||||||.|||.|||||..|:|| ||:....|.|..|.. :
Mosquito 1489 VIAGSQYSLLKSVQPDAASPIHGFNKTVTYSRPIYFCLCCGLLLGIHQLLREYQLDMGRDTVS-I 1552
Fly 1416 VFFGMRYSPADVVALLLQALYIL---LLCFPIIFSVGLCPQINTFLMYLLEQIDMHVFGGNAASS 1477
|.|| ||..:||.|..|..:| :|.||::|.:||.||||||.||.|||:|||:||.||:.|
Mosquito 1553 VLFG---SPISIVAFLQSAQTVLKYVILFFPLLFCLGLFPQINTFTMYFLEQVDMHLFGSNASCS 1614
Fly 1478 LLGSFLCVVRSVLAVMLLYGPLYGALDEQRGTQYILFSIFCAMLVPLGYHLSRCASDFSHLWRLI 1542
||.|||.||||::|..||:|.:||||.| .|||::|||::||.||.:.|||||||||::::|.:|
Mosquito 1615 LLASFLSVVRSIVACTLLFGLVYGALSE-TGTQHVLFSMYCAFLVTVSYHLSRCASDYTYIWAVI 1678
Fly 1543 KTCIVSTYRDDEDEDLSQMQHIATGTVTGSGTANSTALQLTTSTPKQHRQTDVKTEHEQIELSSL 1607
|:.::: |...|..:..|..::||
Mosquito 1679 KSSLLT-----------------------------------------HSDYDDASSKEDSKISS- 1701
Fly 1608 EKLTVNEEHHEKDHGADDQLETDQDLPLQQKHSKSKTSSLGSSQQTLGKTISSSKRAITASSSCT 1672
...|.|.:| .|:||.....:.||::.|
Mosquito 1702 ---------DSGDDGKED----------GQRHSSGDGGAGGSARST------------------- 1728
Fly 1673 SIGTGEPAVEAGALTEEAVEGEEQRRNTLAGEVGSKHELAENYDQAAKIDECEDKISSSSATNPG 1737
.|:..::|:
Mosquito 1729 ------------------------------------DEMNRDFDE-------------------- 1737
Fly 1738 DMSTLTAGAGTATTDATPACLEADPDAEAEAPADEKQHQGILGTGTGTGTGTTEASENGSGGGAN 1802
||..||.|:
Mosquito 1738 ---------------------EAGRDAVAK----------------------------------- 1746
Fly 1803 GNTNSNGTGNDLPDPLPRKLQATVTTRLKNDLVVMTLLAVSVLGLHCSTVFTALQPDLNVVLYSF 1867
:|.||||||||.|||.|||||.||..:|:|::..||||||||.|||::|.||:|.
Mosquito 1747 ----------ELDDPLPRKLQDTVTARLKNDAVVCVVLSVAMFSLHCSTVFTVLQPEINHVLHSG 1801
Fly 1868 IGVLGLLLHYIVPQMRKHMPWLCFSRPLLRQREFGQFEVLNAPKIMWFEKLYIYLSVLERNVLFP 1932
..:||.|:||||||:|||:||||.::|:|:..|||.|||....||||||.:|:.|...|||:|:|
Mosquito 1802 ACILGFLMHYIVPQLRKHLPWLCIAKPILKPEEFGLFEVHKLSKIMWFETMYVVLCFFERNILYP 1866
Fly 1933 LLAISSLTADSQLIVAKFGLPWGTLIVAICALKFVRNAYSDPTNQYLIIIFTVLLFRIDFAMATE 1997
|:.||:||||...|..||||.:|::::.:|:||.|||||||..:||:|:|||||.||.|:.|::|
Mosquito 1867 LIFISALTADCGQIADKFGLTFGSILIVMCSLKCVRNAYSDTGSQYVILIFTVLFFRSDYKMSSE 1931
Fly 1998 TFIIDYFFVSLAFRKCCDFLLKLQFIVTYIAPWQITWGSAFHAFAQPFSVPHSAMLFLQAAISAV 2062
||::|||.:|:.:||..:|||||||:|||||||||||||||||||||||||||||||||.||||:
Mosquito 1932 TFLLDYFLISILYRKIAEFLLKLQFVVTYIAPWQITWGSAFHAFAQPFSVPHSAMLFLQTAISAI 1996
Fly 2063 LSTPLNPFLGSAIFLTSYVRPIKFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLT 2127
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito 1997 LSTPLNPFLGSAIFLTSYVRPIKFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLT 2061
Fly 2128 RSLQHSLCGDLLMGRWGNVNQGDCFVLASDDLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREV 2192
|||||||||||||||||||:||||||||||.||||||||||||||||||||||||||||||||||
Mosquito 2062 RSLQHSLCGDLLMGRWGNVSQGDCFVLASDYLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREV 2126
Fly 2193 EAITEDVEDNDGCCCCDPGHLPQLLSANAMFSTRWLAWQVVAAQYVIEGYSISDNLASATLQVFE 2257
|||:|:||||.|||||..||||::|||||||:||||||||:|::||:||||||||.|:||:||||
Mosquito 2127 EAISEEVEDNIGCCCCTIGHLPRMLSANAMFTTRWLAWQVMASKYVLEGYSISDNSATATMQVFE 2191
Fly 2258 YRKVLITYYIKSIIYYVVKNPKLEQWLASGPIQDALQHTLSRQFVDLDPIFNFNLDEDFDFRAVG 2322
:|||||:||:||||||.:::|||..||.|..|::||:||..||||||||:||.|||:|:|.||.|
Mosquito 2192 FRKVLISYYVKSIIYYTLRSPKLMSWLQSQAIEEALEHTTDRQFVDLDPVFNINLDDDYDSRAAG 2256
Fly 2323 ITRSSFCYVYLKWINYCVDMRRDANSMGGAPPAQAPAAAGGASSAPATAGVAPPAPVTPAHNDSK 2387
||||||..||..||.:|.|.:| ..:..|...:.|....|| |.|||..|.|:..||
Mosquito 2257 ITRSSFWCVYGDWIQFCSDKKR--QQLQAALNERTPRKTTGA--ATATATTAAPSTATP------ 2311
Fly 2388 STPNLSAHGGQAGPSSGQSKSQSQQQLRRPQKSVAQETSVGGGGVVVG---GTTVPGTGGVTGGG 2449
|.....:...|.|.:...::....|.|.:...|..|..|| |:||. .|.:..|.
Mosquito 2312 --------GDSGAGNCFVSSSSNANVMKADSASGATKDGKGSSGGAVGTNTGSTVL-DGWMEAGS 2367
Fly 2450 GDPQLSSSHSFANISRQTSESAPGLGGYVAYMDQNVFVKLAKSSTTTGAGAGAPTSRKESQEKPA 2514
.|.:.....| |.....:.|. .:::|||.|| ||...|
Mosquito 2368 ADSKAECGES----SGTNGNTVPA------------------GTSSTGASAG-------SQANGA 2403
Fly 2515 LRLKLASVG-----------KDAPLVSLCLALGLLARRSLATASHSALTGVEFFLHGLHALFKGD 2568
.....||.| :|:.:.|||::|.|||||:|||||||:..||||||||||||||||
Mosquito 2404 GSTNNASNGSANGTSFFKSNRDSLVTSLCMSLALLARRTLATASHSSSCGVEFFLHGLHALFKGD 2468
Fly 2569 FRITSPRDEWVFADMELLHSVVAPAVKMALKLQQDHITNPDEFLDPHALYDAIDNCSNELVISHE 2633
||||.||||||||||||||.||||||:|:|||.|||...|||:.|...||:|||..:.|||||||
Mosquito 2469 FRITCPRDEWVFADMELLHGVVAPAVRMSLKLHQDHFLCPDEYDDYSNLYNAIDFHTKELVISHE 2533
Fly 2634 ADPVWRSAVLRGAPNLLALRHVMEDGSDEYRIIRLTKRCLSFRVIKLNRECVRGLWAGQQQELIY 2698
|||:||:|||||.||||||||||:|||||||:||||||.|:||||||||||||||||||||||||
Mosquito 2534 ADPLWRNAVLRGTPNLLALRHVMDDGSDEYRVIRLTKRFLTFRVIKLNRECVRGLWAGQQQELIY 2598
Fly 2699 LRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYVSPLTTSYADTNAQLCEVIGGAITLDTIRH 2763
||||||||||||||||||||||||||||||||||||||||||||:||||||.:|||.|||:.|:.
Mosquito 2599 LRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYVSPLTTSYAETNAQLCRIIGGEITLEKIQS 2663
Fly 2764 TVLGWWHRIRERCRQGCSSGSALEPHPGSGPVQLGACNFGSGGSVVGAASTATGVGASTGSGLGV 2828
.::..|.|||:|||:|||||||: :.|..:...||..:|
Mosquito 2664 MLIRIWKRIRQRCREGCSSGSAI---------------------IEGEMTEMQGVYCNT------ 2701
Fly 2829 AAPGTAGSTGGESGDLAPVFISAPLYNTLTVNSYYSVRPGNVPGGPIPGNLGGNYVSDSLAVVRG 2893
|....:..|.:|.|: |..:..::.|. |..||
Mosquito 2702 --PTPNNTLSGTAGTLS-----------------YGSQNMSISGA---------------AATRG 2732
Fly 2894 GLAVMPVKPTSTTLIAGLLNRERDETSGSGIMGAGASGPTRATSSGGVRSR----RPEVGSSRGR 2954
.:|.:. ||||:||:||.|.|||| |.....|..:.|||.| :..|||: .:
Mosquito 2733 SMASIN-KPTSSTLLAGFLIRERD-----------AEREAMAMGTTGVRERSTIAKRNVGST-SK 2784
Fly 2955 DHERRATLPI----------------ASGGAGGEPGKDLTA---PQTQVEHEPSPRSTKLSSSSG 3000
|....|.|.| |:|||.|. |.|.:. .::|.....||.|| ....|
Mosquito 2785 DRIDWAALQINKRDSFREVLAEAVAAAAGGASGS-GNDSSVGADDESQSTAGGSPNST--LKQQG 2846
Fly 3001 SLGLGMGVGLGNIITTPGDYPRKTKGP-ICLTAVDTGTSSSAAEGKPAGSGTVAGT---GVGGVI 3061
|:....|:..| |..|...| ..|:...:|.|::.|.| |:|..||: ||.|.:
Mosquito 2847 SVESTSGLASG--------YVHKANVPSSMLSGGGSGFSAALASG---GNGVAAGSRIPGVPGTL 2900
Fly 3062 ---------------------------------RKPRIEIFKKVIIVDDTGIYDCLDI---IDAV 3090
..|.|.:.|||||||.:.||||||: || |
Mosquito 2901 TFTLSPPDDAPYSLFVMAEAQPDEPKTSVQWMHSPPTIGLNKKVIIVDASQIYDCLDLGRRID-V 2964
Fly 3091 VWPTERMRNNGGRLSWKDWEPSAGMVGHVVHCWTPNHKDIRFRSHVNRYVYLVEIGDHYVPVEEL 3155
.||.|:.|::|||.|||:|.|..||||:|||.|.|||.|..:||:|||.:.||:||:.:||:.|.
Mosquito 2965 TWPNEQFRSSGGRSSWKEWSPQEGMVGNVVHYWQPNHPDHHYRSNVNRTILLVKIGERHVPIGEK 3029
Fly 3156 GLREYNQI-------MGSTEEMANSRRSSIQRDFHEYNIQLKLAGLAPIIGGGESSTATTSDASK 3213
|::|||.| :.:|.:...|.||.:... .:::::.....:...| ..:|||..:||.:.
Mosquito 3030 GIKEYNTIGLVAAETLPTTVQGDESSRSGVAPG-RQHSLEAVSEDITSAI-AVDSSTIVSSDRAS 3092
Fly 3214 SHKAKIRAVSSSSSEDEDTSSTRSIPLPQGDDGD 3247
:....:: ||..||.:.||:|.:|....|.:.:
Mosquito 3093 TEANDMQ--SSPQSETQITSTTGNIASQGGTESE 3124
| 
