Protein Alignment Vinc and vcla

DIOPT Version :9

• Sequence 1: NP_001284813.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_001122153.1
• Gene: vcla / 552980
• ZFINID: ZDB-GENE-050506-61
• Length: 1131
• Species: Danio rerio
• Alignment Length: 1145
• Identity: 468/1145 - (40%)
• Similarity: 641/1145 - (55%)
• Gaps: 199/1145 - (17%)

  Fly     1 MPVFHTKTIESILDPVAQQVSRLVILHEEAE-DGNAMPDLSRPVQVVSAAVANLVKVGRDTINSS 64
            |||||||||||||:|||||:|.|||:|||.| ||.|:|||:.||..|.|||:|||:||::|:.::
Zfish     1 MPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTSPVAAVQAAVSNLVRVGKETVQTT 65

  Fly    65 DDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESE 129
            :|||:::|||||..:||.|...|.||:.|||:||||.|||..||:||||||.|||.|||.|||:|
Zfish    66 EDKIMKRDMPSAFIKVENACAKLVEAAQMLRTDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAE 130

  Fly   130 VRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCL 194
            |||||:.||.:|:||.||||:.|||.|:.:.|:|.|.::|:.:.:..|::|||||.|..:||..:
Zfish   131 VRKIIRVCKGILEYLTVAEVVETMEDLITYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVTSM 195

  Fly   195 EQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDT-SE 258
            ..||.|.|:||.::|:::.....:..|.|||.:||||...:|:.|:.|||||||||::|||. :.
Zfish   196 NTVKELLPVLISAIKIFVTTKCTKSHGVEEALKNRNYTFDKMTAEINEIIRVLQLTSWDEDAWAN 260

  Fly   259 LDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCL---------- 313
            ..:...:|:....|.:||.||..||.:|.||.|..||.||||::|.|.::.|.|.
Zfish   261 KKDTEAMKRALALIESKMGQAKGWLRDPNALPGDPGEHALRQILDEAGKVGELCAGKERREILGT 325

  Fly   314 ----------------------------------------------------------------- 313
                                                                             
Zfish   326 AKTLGQMTDQVSDVRARGQGATPMGMQKAQQVAQGLDILVGKVENAARKLEALTNAKQAIAKRID 390

  Fly   314 ------------PQDSYPIR-------KLAD----------------EVTAMANTLCELRQEGKG 343
                        |:....||       ::||                |:..:...|.|||:.|||
Zfish   391 NAQSWLADPNGGPEGEENIRALLAEAKRIADLCEDPKERDDILRSIGEIAGLTARLVELRRIGKG 455

  Fly   344 QSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEINDGGLGE 408
            .:|:|.:|.:.|...:..|::..::||..:..|   :.|.|::|::|||::|:.:|.::|.|:|:
Zfish   456 DTPEARALAKQIGTALQNLQAKTNRAVANMRPA---KAAVTLEGKMEQALRWINNPGVDDHGVGQ 517

  Fly   409 RAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAA-------GSGPAAKQAAKQLTQKLY 466
            .||..::.|||::|...||..:.|:...|::||:|..|.|       |..|.|:..|..|.:.:.
Zfish   518 AAIRGLIAEGRRLASSLPGPYRQELLAKCEQVEQLMMQLADLAARGEGESPQARAVAAHLLEAIK 582

  Fly   467 ELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRM 531
            :|||.:|.|:...:...|.|.:||:|....|...|...|.||:.|.::::|.:..:.|...|:..
Zfish   583 DLKAKMQEAMTQEVSDVFSDTTTPIKLLAVAATAPLEAPNREEVFEERASNFENHASRLGATAEK 647

  Fly   532 VAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMR 596
            .||.|. .||...|.:.::......||||:.||.||.:..||::||.||...:|.|:.|.:.:|.
Zfish   648 AAAVGT-ANKSTVEGIQAAVKSARDLTPQVTSAARILLKNPGNQAAYEHFDTMKNQWIDNIEKMT 711

  Fly   597 TLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSE 661
            :|.|:|.|....:..|||.::.....|..|:...|||.:|...::|||..||||||||:|.:|||
Zfish   712 SLVDEAIDTKSLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSE 776

  Fly   662 DPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAIAPPQP 726
            ||.|.|.:.||::.|.|::..||..||.||.||.||.....:.:|..|:|..|.:||:|..|.:
Zfish   777 DPKFRELVKAASDELGRTISPMVMAAKGVAGNIQDPGLQKGFLDSGYRILAAVGKVREAFQPQE- 840

  Fly   727 PPLPTSLPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDE-------------- 777
                ...|||.|:|..||:   |.::|||:||||...:.|.||||||..||
Zfish   841 ----LDFPPPPPDLDQLHV---NDDQAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEMVSEP 898

  Fly   778 ----------------------DEG----------------------------VFRTMPHANQPI 792
                                  |||                            :..:....||||
Zfish   899 MMVAARSLHDEARKWSSKPEVPDEGFEAAEAEVDIDDEDEFTDNEDDYEPELLLMSSNQPVNQPI 963

  Fly   793 LIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELVLSDSRGSKRELIATAKKIAEASEDVT 857
            |.||:.||||.|:||||.|:||.||||||:|||.:|.||...| |:||.||..||.||:||::||
Zfish   964 LAAAQSLHQEARKWSSKGNDIIGAAKRMALLMAEMSRLVRGGS-GNKRALIQCAKDIAKASDEVT 1027

  Fly   858 RLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQ--GSDEDREATEMLVGNA 920
            |||||:|:||||:||||||||||||||||.|||||||||||||||..  ..:|..:||||||.||
Zfish  1028 RLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNA 1092

  Fly   921 QNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQ 960
            ||||||||||||.||.||||||:| ....|:|||:.||||
Zfish  1093 QNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_001284813.1	Vinculin	63..960	CDD:279395	422/1080 (39%)
vcla	NP_001122153.1	Vinculin	66..1131	CDD:279395	422/1078 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593570
Domainoid	1	1.000	488	1.000	Domainoid score	I371
eggNOG	1	0.900	-	-		E1_KOG3681
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	537	1.000	Inparanoid score	I1158
OMA	1	1.010	-	-		QHG51903
OrthoDB	1	1.010	-	-		D141915at33208
OrthoFinder	1	1.000	-	-		FOG0005827
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106307
Panther	1	1.100	-	-	LDO	PTHR46180
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4095
SonicParanoid	1	1.000	-	-		X4806
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.800