Protein Alignment Vinc and Ctnna3

DIOPT Version :9

• Sequence 1: NP_001284813.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_038955205.1
• Gene: Ctnna3 / 361839
• RGDID: 1562230
• Length: 914
• Species: Rattus norvegicus
• Alignment Length: 1014
• Identity: 206/1014 - (20%)
• Similarity: 383/1014 - (37%)
• Gaps: 267/1014 - (26%)

  Fly     6 TKTIESILDPVAQQVSRLVILHEEAEDGNAMPDLSRPVQVVSAAVA----NLVKVGRDTINSSDD 66
            |.|:|.:|:|:..||:.||...:  ...|.....|:..:|:.|:|.    ||:..|.  :.:.:.
  Rat    39 TFTVEKLLEPLIIQVTTLVNCPQ--NPSNRKKGRSKRARVLLASVEEATWNLLDKGE--MIAKEA 99

  Fly    67 KILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVR 131
            .:|::|:.:||..|...|:.|:.:::....||...|.|:.:::.:|.:|...:.||:..|.::|.
  Rat   100 TVLKEDLEAALQEVRKESKALKGSAERFTDDPCYLPKREAVVQAARALLAAVTRLLILADMTDVM 164

  Fly   132 KIIQECKRVLDYLAVAEVINTMEQLVQFLKDLS--PCLSKVHREVG-----------AREKELTH 183
            .::|.             :::.::..:.||::|  ..|.|.::::|           .|:::|..
  Rat   165 CLLQH-------------VSSFQRTFKSLKNVSNKSDLQKTYQKLGKELERLDRFAFKRQQDLKS 216

  Fly   184 QVHSEILVRCLEQVKTLAPIL--ICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRV 246
            ....:.:......:|..:|:|  |||.     .:|.....:.:|:::      .:.:|:|..:.|
  Rat   217 PSQRDEIAGARATLKENSPLLHSICSA-----CLEHSDVASLKASKD------TVCEEIQNALDV 270

  Fly   247 L----------------QLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGE 295
            :                |..|......||:||.||        |.:....|.|..|.       |
  Rat   271 ISNASQGIQNVPASLEPQAATLGSALDELENLIVL--------NPLTVTEEDLRPPL-------E 320

  Fly   296 KALRQVIDNATEISERCLPQDSYPIRKLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMG 360
            |.|..:|..|..:::....:|.:..|.:|                      :..::.:.::|.:.
  Rat   321 KRLEAIISGAALLADSSCTRDLHRERIIA----------------------ECNAIRQALQDLLS 363

  Fly   361 ELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGC 425
            |..|.:                                      |..||:..|
  Rat   364 EYMSNI--------------------------------------GKTERSNTL------------ 378

  Fly   426 PGHQKAEIQQLCDEVERLKRQAAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTP 490
                                         ..|...:::|..:|:..::.|:::.|...|:|.:.|
  Rat   379 -----------------------------NTAIVNMSKKTRDLRRQLRKAIIDHISDSFLDTTVP 414

  Fly   491 LKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRAS----KTSR-MVAAGGACG---NKKIAEIL 547
            |....||.               |:..::...|.||    .|.| |..|..||.   |:...:|:
  Rat   415 LLVLIEAA---------------KNGQVKEIKDYASIFHEHTGRLMEVANLACSMSTNEDGIKIV 464

  Fly   548 LSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTS 612
            ..:|..:::|.||:|:|.....:.|.|:.....::..|:.:...:..:....|..|...||:..|
  Rat   465 RIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVDDITSIDDFLAVS 529

  Fly   613 EEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLIN----RVLLVAKQEADNSEDPVFTERLNAAA 673
            |.|:......|..|:..:.    .||....|..|.    ||..:...|.|:.|...:||.:....
  Rat   530 ESHILEDVNRCIIALRDQD----ADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNV 590

  Fly   674 NRLER-SLPAMVGDAKLVATNIADPAAAAAWKNSF----QRLLGDVREVRDAIAPPQPPPLPTSL 733
            |.|.. .:|..|....:....::..|..|...|.|    :::...:.::|.::       :....
  Rat   591 NLLTSIVIPEFVTQVNVALDALSKNALTALDDNQFVDISKKIYDTIHDIRCSV-------MIIRT 648

  Fly   734 PPPIPELSAL--------HLSNQ---NAERA--PPRPPLPREGLAPVRPPPPETDDEDEGVFRTM 785
            |..:.::|.|        |.|.|   ..:||  ...|...:|.:|           |....|:.:
  Rat   649 PEELEDVSDLEDDHEVRSHTSTQTEGKTDRAKMTQLPEAEKEKIA-----------EQVADFKKV 702

  Fly   786 PHANQPILIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELVLSDSRGS-----KRELIAT 845
            ...          |..|:..|....|:||..||:|.::|..:::.    :||.     ..::|..
  Rat   703 KSK----------LDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDF----TRGKGPLKHTTDVIYA 753

  Fly   846 AKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATM--LGAQGSDE 908
            ||.|:|:...:..||:::|.||.|...:.:||...|:|.....||||.|.|||.:  ||.:....
  Rat   754 AKMISESGSRMDVLARQIANQCPDPPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVS 818

  Fly   909 DREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTS 947
            ..::...|:..|:|||.:|.:||:.:..||.||...|:|
  Rat   819 ALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSS 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_001284813.1	Vinculin	63..960	CDD:279395	189/953 (20%)
Ctnna3	XP_038955205.1	Vinculin	102..875	CDD:395830	189/947 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910