Protein Alignment Vinc and Ctnna2

DIOPT Version :9

• Sequence 1: NP_001284813.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_017448033.1
• Gene: Ctnna2 / 297357
• RGDID: 1305060
• Length: 966
• Species: Rattus norvegicus
• Alignment Length: 1052
• Identity: 218/1052 - (20%)
• Similarity: 394/1052 - (37%)
• Gaps: 261/1052 - (24%)

  Fly     6 TKTIESILDPVAQQVSRLVILHEEAEDGNAMPDLSRPVQVVSAAV----ANLVKVGRDTINSSDD 66
            |.|:|.:|:|:..||:.||....:...|. ....|:...|::|:|    .|.::.|......|.|
  Rat    34 TLTVERLLEPLVTQVTTLVNTSNKGPSGK-KKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQD 97

  Fly    67 KILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVR 131
              |::::.:|:..|....:.:..||.....||.|...|..::..:|.:|...:.||:..|.::|.
  Rat    98 --LKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVM 160

  Fly   132 KIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQ 196
            :::...|.|.:.|...:.....:.|....|:....:.|::.....|::||......:.:......
  Rat   161 RLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGA 225

  Fly   197 VKTLAPILICSMKVYIHIVEQQGRGAEEAA--ENRNYLAARMSDELQEIIRVLQLTTYDEDTSEL 259
            :|..|.:|..:.:.::       |..:.||  .||:|:..::.:.:..|....|.|:..::....
  Rat   226 LKKNATMLYTASQAFL-------RHPDVAATRANRDYVFKQVQEAIAGISSAAQATSPTDEAKGH 283

  Fly   260 DNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQDSYPIRKLA 324
            ..:..|....|...||:                        ::|..|....|..|.....:..:.
  Rat   284 TGIGELAAALNEFDNKI------------------------ILDPMTFSEARFRPSLEERLESII 324

  Fly   325 DEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRL 389
            .....||::.|                   .||...|  .:|.:.                 ..:
  Rat   325 SGAALMADSSC-------------------TRDDRRE--RIVAEC-----------------NAV 351

  Fly   390 EQAVKWLQHPEINDGGLGERA--INLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSGP 452
            .||::.|....:|:.|..|:.  :|:.::
  Rat   352 RQALQDLLSEYMNNTGRKEKGDPLNIAID------------------------------------ 380

  Fly   453 AAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNN 517
                   ::|:|..:|:..::.|:::.|...|::.:.||....||     ...|.|:...:.:
  Rat   381 -------KMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEA-----AKSGNEKEVKEYA-- 431

  Fly   518 LQAFSDRASKTSRMVAAGGAC---GNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADE 579
             |.|.:.|:|.  :..|..||   .|::..:::..:|.|:|||.||:|:|.......|.||.|.:
  Rat   432 -QVFREHANKL--VEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQD 493

  Fly   580 HLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIAR 644
            ::...|.|:...|..:....|..|...||:..||.|:......|..|:.    :..||.....|.
  Rat   494 NMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQ----EGDVDTLDRTAG 554

  Fly   645 LIN----RVLLVAKQEADNSEDPVFTERLNAAANRL-ERSLPAMVGDAKL----VATNIADPAAA 700
            .|.    ||:.:...|.:|.|..|:||::..|...| |..:|......::    ::.|:..|..
  Rat   555 AIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFE- 618

  Fly   701 AAWKNSF---QRLLGD-VREVRDAIAPPQPPP----------------LPTSLPPPIPELSALHL 745
               :|.|   .||:.| ||::|.|:...:.|.                ..||:.....:|    :
  Rat   619 ---ENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQL----I 676

  Fly   746 SNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGLHQEVRQWSSKD 810
            :.|:|.....:  ||:|..|.:.        |...:|    |..:..|.|      ||.:|....
  Rat   677 AGQSARAIMAQ--LPQEEKAKIA--------EQVEIF----HQEKSKLDA------EVAKWDDSG 721

  Fly   811 NEIIAAAKRMAILMARLSELVLSDSRG-----SKRELIATAKKIAEASEDVTRLAKELARQCTDR 870
            |:||..||:|.::|..:::.    :||     :..::|..|||||||...:.:||:.:|.||.|.
  Rat   722 NDIIVLAKQMCMIMMEMTDF----TRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDS 782

  Fly   871 RIRTNLLQVCERIPTIGTQLKILSTVKATM----------------------------------- 900
            ..:.:||...:||.....||.|.|.|||.:
  Rat   783 ACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTGVQSTFTTFYEVDCDVIDGGRAS 847

  Fly   901 --------------LGAQGSDEDR-EATEMLVGNAQNLMQSVKETVRAAEGASIKIR-----SDQ 945
                          :|:..||... ::...|:..|:|||.:|..||:|:..||.|.:     :..
  Rat   848 QLSTHLPTCAEGAPIGSGSSDSSMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAV 912

  Fly   946 TSNRLQWVRRQP 957
            .|..:.|..:.|
  Rat   913 NSPVVSWKMKAP 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_001284813.1	Vinculin	63..960	CDD:279395	202/991 (20%)
Ctnna2	XP_017448033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910