Protein Alignment Vinc and deb-1

DIOPT Version :9

• Sequence 1: NP_001284813.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_001293743.1
• Gene: deb-1 / 177482
• WormBaseID: WBGene00000942
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1099
• Identity: 498/1099 - (45%)
• Similarity: 675/1099 - (61%)
• Gaps: 147/1099 - (13%)

  Fly     1 MPVFHTKTIESILDPVAQQ---------------------------------------------- 19
            ||||||||||:||:|||||
 Worm     1 MPVFHTKTIENILEPVAQQLHYVLAMAEKNATSVDEVRHLGTSMPNLDRFASRSALALSRASSRR 65

  Fly    20 ----------------------------------VSRLVILHEEAEDGNAMPDLSRPVQVVSAAV 50
                                              |||||||||||.||||||||:.||.:||.||
 Worm    66 SIPEYITPDTVRHVVNDDDCPVCQLMMPRGKDGCVSRLVILHEEANDGNAMPDLTGPVGMVSRAV 130

  Fly    51 ANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGIL 115
            .||::||.||.:.|||:||:||||.||.||||:|:||||:|..|:.||||.|||||||:|:||||
 Worm   131 GNLIQVGYDTCDHSDDRILQQDMPPALQRVEGSSKLLEESSYSLKHDPYSVPARKKLIDGARGIL 195

  Fly   116 QGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKE 180
            ||||:||||||||||||||:.|::..||:||:|||.:|..|.||:||:||.|..|..:|..|::|
 Worm   196 QGTSALLLCFDESEVRKIIRVCRKANDYVAVSEVIESMADLQQFVKDISPVLHDVTNDVNLRQQE 260

  Fly   181 LTHQVHSEILVRCLEQVKTLAPILICSMKVYIHIVEQQGR-GAEEAAENRNYLAARMSDELQEII 244
            ||||||.|||:||::.:|.:|||||||||..|.:.....| |..||..|||:::.||::|:.|||
 Worm   261 LTHQVHREILIRCMDSIKVIAPILICSMKTSIELGTPHPRQGHAEAIANRNFMSQRMTEEMNEII 325

  Fly   245 RVLQLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEIS 309
            |||||||||||..:.||:||::|..:|..:.:..|.:||::|:|..|.|||||:|::.:.|..||
 Worm   326 RVLQLTTYDEDEWDADNVTVMRKALSAAKSLLTAALDWLADPHARSGAVGEKAIRRICEYADRIS 390

  Fly   310 ERCLPQDSYPIRKLADEVTAMANTLCELRQEGKGQSPQAESL----VRGIRDRMGELKS--LVHQ 368
            .|.||:|:..|::...|:|:..:.||.||..|:   |..|:|    .|.::|.:|...|  |:..
 Worm   391 ARALPEDAQSIKRSIFEITSFTDELCNLRNNGQ---PDRENLAAQTARRLKDLVGSQNSSGLMGD 452

  Fly   369 AVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEI 433
            |:....:.|....|||..||||||::||.:|.::|||||.:|:.|:..:.||:|:......:..:
 Worm   453 ALQNAQRHGGANPAHTAAGRLEQALRWLDNPGLDDGGLGLQALRLLTADARKLADRLNPQDRNRL 517

  Fly   434 QQLCDEVER-------LKRQAAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPL 491
            ..||.:::|       |:|:..|:.|.|.|...||...|.:|...::..|.:|:|.||.|::|||
 Worm   518 LGLCSDIDRLAAQLADLERRGLGNSPEAHQIRNQLKNALRDLGDFMRRVLTDRVVDDFADITTPL 582

  Fly   492 KQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDS 556
            |||.|||......|.|||||..||..|...|...:.|:|:||:.|...:||..|.:|.:|.:|:.
 Worm   583 KQFVEAVHADPYDPNREQNFVDKSQRLTDHSQSMTTTARLVASCGPSKSKKTVEAILDTAEKVEQ 647

  Fly   557 LTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAK 621
            |||||::|||:|::.|||   ::|.:|:.:||||.:.|:|:..|.|.|..:|::.||..|:.|..
 Worm   648 LTPQLVNAGRVRLHNPGS---EQHFENIHKQYADALHRLRSHVDDAIDTGEFVRASETAMRRYTN 709

  Fly   622 LCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGD 686
            .||.||:......:|:|:|.||||.||||:.|:.||||||:|.|..|:..||::|..::|.||.:
 Worm   710 HCEGAINGADAHGLVNNSSQIARLGNRVLMTAQNEADNSEEPSFVSRVRNAADQLHNAIPPMVNN 774

  Fly   687 AKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAI-------------------APPQPPPLPTS 732
            ||.:|.|..|..||..|:.:...||..||.|.|||                   |.|..||.|:|
 Worm   775 AKQIAQNPHDQYAAQNWRGTNDHLLNSVRAVGDAITGVPMSNGRHSSYQESISRASPYNPPPPSS 839

  Fly   733 --------LPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFR-----T 784
                    .||..|.:....:..::.. ||||||.|.|...|.|||||...||:|....     .
 Worm   840 QVIRSVNASPPTAPIIHNKMIIREDIP-APPRPPPPVELSPPPRPPPPPEYDEEEETRAFWERYP 903

  Fly   785 MPHA-NQPILIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELVLSDSRGSKRELIATAKK 848
            :|.| :||:|.||..||.|::||||::|:|:||||||||||||||:||..:. |:|::||..:|.
 Worm   904 LPQASHQPMLAAAHNLHNELKQWSSQENDIVAAAKRMAILMARLSQLVRGEG-GTKKDLINCSKA 967

  Fly   849 IAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLGA---------- 903
            ||::||:|||||.:|||.|||.::||.||||.||||||.||||:||||||||||:
 Worm   968 IADSSEEVTRLAVQLARLCTDIKMRTALLQVSERIPTIATQLKVLSTVKATMLGSANVIGPYGQP 1032

  Fly   904 -QGSDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQY 961
             :||:||.||.:.||.||||||||||:.|||||.||||||:: :..||:|:|:..|..:
 Worm  1033 VEGSEEDDEAMQQLVHNAQNLMQSVKDVVRAAEAASIKIRTN-SGLRLRWLRKPMWSNF 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vinc	NP_001284813.1	Vinculin	63..960	CDD:279395	450/954 (47%)
deb-1	NP_001293743.1	Vinculin	100..1089	CDD:366435	481/997 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165724
Domainoid	1	1.000	844	1.000	Domainoid score	I21
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H70886
Inparanoid	1	1.050	852	1.000	Inparanoid score	I223
Isobase	1	0.950	-	0	Normalized mean entropy	S4383
OMA	1	1.010	-	-		QHG51903
OrthoDB	1	1.010	-	-		D141915at33208
OrthoFinder	1	1.000	-	-		FOG0005827
OrthoInspector	1	1.000	-	-		oto18476
orthoMCL	1	0.900	-	-		OOG6_106307
Panther	1	1.100	-	-	LDO	PTHR46180
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4095
SonicParanoid	1	1.000	-	-		X4806
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.890