Protein Alignment SmydA-8 and Smyd4-3

DIOPT Version :10

• Sequence 1: NP_001014717.1
• Gene: SmydA-8 / 31200
• FlyBaseID: FBgn0053548
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_725048.1
• Gene: Smyd4-3 / 36234
• FlyBaseID: FBgn0033633
• Length: 660
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 89/441 - (20%)
• Similarity: 145/441 - (32%)
• Gaps: 132/441 - (29%)

  Fly    59 ISSSTVAGRGVFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQTGFLCRHRCTLPV 123
            |.|:...||...|:.|:..||.:..||..|: ....|...:.|..|        |:   |..:||
  Fly   243 IDSNRQEGRFARASADVKPGEELLVERPFVS-VLLEKFAKTHCENC--------FM---RTVVPV 295

  Fly   124 -CETCSD----SEE---------HQAEC---------------------------EHFRRWQPKD 147
             |..|:|    ||:         |:.||                           ::|.:.:| .
  Fly   296 ACPRCADVLYCSEQCREEASKKYHKYECGIVPIIWRSGASINNHIALRIIASKPLDYFLKLKP-T 359

  Fly   148 VDAEQEQVNPMSL---------RILTAVRVFHLGKEQ-----RHLVDAMQANAERAYRREIIQAA 198
            :|   |::.|..|         |:....|  |.|:.|     :|::.|       .:....::|.
  Fly   360 ID---EELTPEQLISLPKDDFRRVAQLER--HQGERQPSNFFQHVLMA-------RFLTNCLRAG 412

  Fly   199 QCFRNFPTTDRV--FMDQLFRIVGVLNTNAFEAP-----CRSGGHETLLRG--LFPLTAIMNHEC 254
            ..|.:.|..|.|  ....:.|.:..:..|..|..     ..||..:::..|  ::|..|:.||.|
  Fly   413 GYFGSEPKPDEVSIICSLVLRSLQFIQFNTHEVAELHKFSSSGREKSIFIGGAIYPTLALFNHSC 477

  Fly   255 TPNASHYFENGRLAVVRAARDIPKGGEITTTYTKILWGN--LTRNIFLKMTKHFACDCVRCHDN- 316
            .|....|| .|....:.:.|.|..|..|...|..:...:  ..|...||....|.|.|..|.||
  Fly   478 DPGVVRYF-RGTTIHINSVRPIEAGLPINENYGPMYTQDERSERQARLKDLYWFECSCDACIDNW 541

  Fly   317 --------------TENGTYLSALFCREQGCRGLVIPVQTRTLQPDWRCITC---ENVFPHAKMA 364
                          .:.....||:......|...::           :|:||   .|:....|:.
  Fly   542 PKFDDLPRDVIRFRCDAPNNCSAVIEVPPSCNDFMV-----------KCVTCGEITNILKGLKVM 595

  Fly   365 KYQDFALNTINNRINS-------CSVQDMIHFINELC----PRFCPSSNYV 404
            :..:....|......:       ....|:|..:.|:.    |.||.|..::
  Fly   596 QDTEMMTRTAKRLYETGEYPKALAKFVDLIRIMYEVLAPPFPDFCESQQHL 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-8	NP_001014717.1	SET	58..>88	CDD:394802	10/28 (36%)
		SET_SMYD	<224..313	CDD:380997	25/97 (26%)
Smyd4-3	NP_725048.1	TPR repeat	74..103	CDD:276809
		TPR repeat	108..142	CDD:276809
		TPR repeat	150..177	CDD:276809
		SET_SMYD4	235..537	CDD:380934	70/319 (22%)
		zf-MYND	284..323	CDD:460312	12/49 (24%)