DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-8 and smyd1a

DIOPT Version :9

Sequence 1:	NP_001014717.1	Gene:	SmydA-8 / 31200	FlyBaseID:	FBgn0053548	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_991103.2	Gene:	smyd1a / 321245	ZFINID:	ZDB-GENE-030131-9825	Length:	485	Species:	Danio rerio

Alignment Length:	419	Identity:	97/419 - (23%)
Similarity:	166/419 - (39%)	Gaps:	87/419 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GRGVFATRDIAAGELIFQE---RALVTGPTARKGQLSSCICC--HETLPQTGFLCR--HRCTLPV 123
            |||:..|||::|||::|.|   .|:|....:    |..|..|  .:..|.....|:  |.|.
Zfish    18 GRGLRGTRDLSAGEVVFAEASFAAVVLDSLS----LQVCHSCFRRQVNPHRCAQCKFAHYCD--- 75

  Fly   124 CETCSDS--EEHQAECEHFRRWQPKDVDAEQEQVNPMSLRILTAVRVFHLG---KEQRHLVDAMQ 183
             .||..:  :||:.||...|...    .|..|.|. :..|||..::. |.|   ..|...:|.::
Zfish    76 -RTCQRAAWDEHRKECSAIRNIG----KAPNENVR-LVARILWRIQK-HTGLVSDSQLTTLDMLE 133

  Fly   184 ANAERAYRREIIQAAQCFRNFPT-----TDRVFMDQLFRIVGVLNTNAFEAPCRSGGHETLLRGL 243
            .:..|....::.:.....:.|.|     :..|..|.:..:.||::.|.|....:. |.:::..||
Zfish   134 DHLSRMTPEDLKELKVDVKTFYTYWPKKSKAVGEDYVSHLFGVISCNGFTLSDQR-GLQSVGIGL 197

  Fly   244 FPLTAIMNHECTPNA----SH--------YFENGRLAVVRAARDIPKGGEITTTYTKILWGNLTR 296
            ||...::||:|.||.    :|        .|.:.|...:||...|..|.|:|.:|...|..:..|
Zfish   198 FPNLCLVNHDCWPNCTVILNHGDQSALDASFHSSRRIELRALEPISAGQELTVSYVDFLSVSTDR 262

  Fly   297 NIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGCRGLVIPVQTRTLQPDWRCITCENVFPHA 361
            ...|:...:|.|.|..|.:.|:: ..::|:...|.|.:                        |.|
Zfish   263 QRLLQQQYYFDCKCEHCVNGTKD-ELMTAVKPTEDGKQ------------------------PSA 302

  Fly   362 KMAK-YQDFALNTINNRINSCSVQDMIHFINELC--------PRFCPSSNYVL--IEAKLNVIWR 415
            ::.| ..||:|..: .:|.:...|...|.:..:|        |.|..::.:||  :.....|:..
Zfish   303 EVVKQLTDFSLQAL-VKIEAARAQGNFHEVIRICRECLEKQDPVFADTNVHVLRVLSTASEVLSF 366

  Fly   416 MTRFDHEEYTPEEMGHMDRYREEVLAILH 444
            :.:|.      |..|:..|..:..:.:.|
Zfish   367 LQQFQ------EAAGYAQRMVDGYMKLYH 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-8	NP_001014717.1	SET	<189..293	CDD:214614	29/120 (24%)
smyd1a	NP_991103.2	zf-MYND	52..90	CDD:280009	10/41 (24%)
smyd1a	NP_991103.2	SET	<203..252	CDD:279228	14/48 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582762
Domainoid	1	1.000	54	1.000	Domainoid score	I11197
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750