Protein Alignment Mct1 and SLC16A3

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001035887.1
• Gene: SLC16A3 / 9123
• HGNCID: 10924
• Length: 465
• Species: Homo sapiens
• Alignment Length: 617
• Identity: 138/617 - (22%)
• Similarity: 237/617 - (38%)
• Gaps: 219/617 - (35%)

  Fly    22 MERQPT---PPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASI 79
            ::..||   .|||||||.|:||.|:|    .|.:|:|    .:|:.|.:..|..|...||||:||
Human     6 VDEGPTGVKAPDGGWGWAVLFGCFVI----TGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSI 66

  Fly    80 MVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYL 144
            ::.:.:.:||:.|..|||:|||.|.:.|.:.|:..::.:.|.::::.:.:|.|..||||..|.:.
Human    67 LLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQ 131

  Fly   145 PAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAM 209
            |:::.:.:||..:|.:|.|:|..||.......:||.:.|...|||||..||:||::|||.:..|:
Human   132 PSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAAL 196

  Fly   210 FRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGAL 274
            .|||.:.|.|.:.|..||
Human   197 MRPLVVTAQPGSGPPRPS----------------------------------------------- 214

  Fly   275 CRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRER 339
                                                                             
Human   215 ----------------------------------------------------------------- 214

  Fly   340 SASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCI 404
                                                                             
Human   215 ----------------------------------------------------------------- 214

  Fly   405 TCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLIST 469
                      ..:::.|:.:|..||:::|:.....:|..||.::||:||:.|.:..|.|::|::.
Human   215 ----------RRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTI 269

  Fly   470 IGVANTVGRIILGYISDKPWVNRLLVYNVCLTAC-----GVSTAMVPLCHDFQSLAFYCCVFGFT 529
            :|..:...|...|:::.   :.::..|:|.|.:.     |::........|:..|..:|..||.:
Human   270 LGFIDIFARPAAGFVAG---LGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGIS 331

  Fly   530 IGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIA 594
            .|....|...:|:.::|..|.::|.||:||.:.:|..:|||.||.:.|.|..|...|::||..:.
Human   332 YGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVL 396

  Fly   595 ISGLVM-----FAIPPLQRLQVRKSERKPHTE 621
            .|.|::     |.|        ||..::|..|
Human   397 TSSLILLLGNFFCI--------RKKPKEPQPE 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	65/181 (36%)
		MFS	<426..604	CDD:119392	51/187 (27%)
SLC16A3	NP_001035887.1	2A0111	8..444	CDD:331689	138/615 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..438		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145569
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850