Protein Alignment Mct1 and SLC16A5

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_005257847.1
• Gene: SLC16A5 / 9121
• HGNCID: 10926
• Length: 545
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 132/606 - (21%)
• Similarity: 220/606 - (36%)
• Gaps: 197/606 - (32%)

  Fly     6 PARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYF 66
            |.:|:.|:..:|.|.        .||.|.|||:..:    :||.|:|..|    |||:.|....|
Human    33 PWQRRQQRMPQALER--------ADGSWAWVVLLAT----MVTQGLTLGFPTCIGIFFTELQWEF 85

  Fly    67 NEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITI 131
            ......|:|..||:..|...:||:.|..|.|:|||...:.|.:||:..::.|.|:.|:..|..|.
Human    86 QASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTA 150

  Fly   132 GFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLII 196
            ||.||||....:..:|..:..||..:|.||..:|..|...|..::..|:.:|:.|.||||..|:.
Human   151 GFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVF 215

  Fly   197 GGIVLNCIIFGAMFRPLELEAPPQT---PPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQY 258
            |||.|:|.|.||:.||:.....|:|   ||..|.||.|
Human   216 GGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPAL--------------------------- 253

  Fly   259 LQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKC 323
                                                                             
Human   254 ----------------------------------------------------------------- 253

  Fly   324 HSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQS 388
                                                                             
Human   254 ----------------------------------------------------------------- 253

  Fly   389 NNVSQSQEEAKCCGCI-TCSKETRDTFAEMMNFSLLK-DMVFVIFSVSNFCTSIGFNVPYLYVVA 451
                         ||: .|.:    |....:.|.:|: :..:.::.:....:.:||.:|.:::|.
Human   254 -------------GCLAACGR----TIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVP 301

  Fly   452 YAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWV--NRLLVYNVCLTACGVSTAMVPLCH 514
            ||....:.:..|:.|||.||.:|...|.:.|.::.:|..  :|..::::.|...|::..:.....
Human   302 YAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASG 366

  Fly   515 DFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLT 579
            ||..|..||..:..::.....|...:|:|::.:|:...|.||..:..|:|..|.||:.|.:.|.|
Human   367 DFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDAT 431

  Fly   580 DSYAPAFLMAGLMIAISGLVM 600
            ::::..|.|:...:..:.|.|
Human   432 NNFSYVFYMSSFFLISAALFM 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	66/181 (36%)
		MFS	<426..604	CDD:119392	43/177 (24%)
SLC16A5	XP_005257847.1	2A0113	41..493	CDD:273325	129/598 (22%)
		MFS	54..452	CDD:119392	123/575 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.750