Protein Alignment Mct1 and ESBP6

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_014274.1
• Gene: ESBP6 / 855598
• SGDID: S000005069
• Length: 673
• Species: Saccharomyces cerevisiae
• Alignment Length: 607
• Identity: 113/607 - (18%)
• Similarity: 210/607 - (34%)
• Gaps: 205/607 - (33%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSG---- 88
            |||||:||||.|..|:....|.|...|||:....:|:: :...|.:.:..:::.|:|...|
Yeast   206 PPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNH-DTYPGASKYDYALIAGLTVFLGQLLS 269

  Fly    89 PISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQY 153
            |:..:.:...|.|...:.|..:..:..:::.|...:..|.:|.||..|....||::||...:..:
Yeast   270 PLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGW 334

  Fly   154 FEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYG-WRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            |..||::|.|:::.|:|.|..|:...|..::.::| .|..:.|||   ::|.|...:...|..|.
Yeast   335 FLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIG---ISCSISVLVAIALLKER 396

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
            .|        ||.:..||       ..|..|.||.:                            .
Yeast   397 NP--------TPAIGLKS-------PRAMFEQLKAM----------------------------F 418

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
            :||                 ::|.|..|:
Yeast   419 SLK-----------------VITKPFVVL------------------------------------ 430

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
             .||:
Yeast   431 -IALW------------------------------------------------------------ 434

  Fly   413 TFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVG 477
                         .:|.:|:         :|:....:.:||.:..|:..|||.|.:.:..:.::|
Yeast   435 -------------FMFALFA---------YNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIG 477

  Fly   478 RIILGYISDK-PWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVIL 541
            |.::|...|| ...|..:|....||.. :....:| .|.|..|.|:..:.|..:|....:.:|::
Yeast   478 RPLMGLAGDKFGRANVTIVLTTLLTIY-MFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLI 540

  Fly   542 VDLLGLDKLTNAFG--------LLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGL 598
            .|::..::...|:.        .||:.:.||..:...     .|.::.|..|.:..|... |:.|
Yeast   541 ADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVE-----KDKSNPYLHAQIFCGCCF-IAAL 599

  Fly   599 VMFAIPPLQRLQVRKSERKPHT 620
            ::.:|.....::::.:||:..|
Yeast   600 ILISILREYSIRMKLTERQAMT 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	46/182 (25%)
		MFS	<426..604	CDD:119392	39/186 (21%)
ESBP6	NP_014274.1	MFS_MCT_SLC16	212..606	CDD:340910	105/584 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1250
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2106
SonicParanoid	1	1.000	-	-		X70
TreeFam	0	0.000	Not matched by this tool.
	8	7.990