Protein Alignment Mct1 and MCH5

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_014951.4
• Gene: MCH5 / 854483
• SGDID: S000005833
• Length: 521
• Species: Saccharomyces cerevisiae
• Alignment Length: 597
• Identity: 109/597 - (18%)
• Similarity: 184/597 - (30%)
• Gaps: 219/597 - (36%)

  Fly    29 PDGGW-GWVVVFGSFMIHIVTDGMTYSFGIFYNEFLD--YFNEGKGYTAWIASIMVGVTFSSGPI 90
            |:||: .|||.||.|:..|...|:..|.|:..:...|  ..:|......|:.|:.:.|..:|..|
Yeast   100 PEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCII 164

  Fly    91 SSSFVNRYGCRAVTIAGSILAASCIIVSMFA--------QNVLTLIITIGFGTGLGFGLIYLPAI 147
            |.::.:|.|.|.:.|.|::..    :..:||        ..:|:..|..|||.|     |.|..:
Yeast   165 SGTYFDRNGFRTIMIVGTVFH----VAGLFATANSTKYWHFILSFAIVCGFGNG-----IVLSPL 220

  Fly   148 VSV-TQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFR 211
            ||| ..||..:|..|..:|..|..                         :||:|     |..|.|
Yeast   221 VSVPAHYFFKRRGTALAMATIGGS-------------------------VGGVV-----FPIMLR 255

  Fly   212 PLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCR 276
            ..                 .:.||   |.:.|...:..::.|   .:|.|
Yeast   256 SF-----------------FSMKS---DTDPTYGFVWGIRTL---GFLDL--------------- 282

  Fly   277 SNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSA 341
                                     .|:|....:||                         ||
Yeast   283 -------------------------ALLTLSIILVK-------------------------ER-- 295

  Fly   342 SGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITC 406
                             ||..:.:
Yeast   296 -----------------LPHVIEN----------------------------------------- 302

  Fly   407 SKETRDTFAEMMNFSLLK--------DMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDA 463
            ||:....:..::...:|:        ||.::...:....:.:..|....|..:||.:..::..||
Yeast   303 SKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDA 367

  Fly   464 SYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCL-TACGVSTAM----VPLCHDFQSLAFYC 523
            ..||..|.|....||.:.||:|||  ..|   :||.: |...:...|    :|...:..::....
Yeast   368 YTLIMIINVCGIPGRWVPGYLSDK--FGR---FNVAIATLLTLFIVMFVGWLPFGTNLTNMYVIS 427

  Fly   524 CVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDL--TDSYAPAF 586
            .::||..|:...|..|....:...::....:..:....|..:.:|.||.|.:..:  |..|....
Yeast   428 ALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYI 492

  Fly   587 LMAGLMIAISGL 598
            :..||...:|.:
Yeast   493 IFCGLATFVSAV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	48/188 (26%)
		MFS	<426..604	CDD:119392	39/180 (22%)
MCH5	NP_014951.4	MFS_MCT_SLC16	106..510	CDD:340910	106/591 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343228
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840