Protein Alignment Mct1 and MCH4

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_014522.1
• Gene: MCH4 / 854030
• SGDID: S000005479
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 550
• Identity: 97/550 - (17%)
• Similarity: 176/550 - (32%)
• Gaps: 187/550 - (34%)

  Fly    29 PDGGW-GWVVVFGSFMIHIVTDGMTYSFGIF--YNEFLDYFNEGKGYTAWIASIMVGVTFSSGPI 90
            ||||. .|:||||:||..:...|:..|.|..  |.......|......:||.|:.:.::|.|..:
Yeast    90 PDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCIL 154

  Fly    91 SSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFE 155
            |..:.:|.|...:...|:::.|..:......::|...|:.....:|||.|::..|.|.:|..:|.
Yeast   155 SGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFL 219

  Fly   156 AKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQ 220
            .:|.:||.|:..|...|..||..:...|....|::.|:.|:..|.|.|:|.
Yeast   220 KRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLIC-------------- 270

  Fly   221 TPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLK 285
                          ::::.:..|...::|.|
Yeast   271 --------------ASVLARERTKPVVQPFK---------------------------------- 287

  Fly   286 PNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDA 350
                                         |..::|:.
Yeast   288 -----------------------------SKAEVAKW---------------------------- 295

  Fly   351 LYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFA 415
                       |:||..:....:.|..:....|:         |..|:....|.|
Yeast   296 -----------YISSVFNWRYFLEGKFLFVAIGA---------SFAESSLTSCAT---------- 330

  Fly   416 EMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRII 480
                                            |:.:|:.|...|:..|..:|:.......:||.|
Yeast   331 --------------------------------YLASYSMTRGNTENVAYTMITASNAVGILGRYI 363

  Fly   481 LGYISDKPWVNRLLVYNVCLTACGVSTAM--VPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVD 543
            .||.:|| ::.|..|..:.::...:...:  :|...:.:.|..|.|::||:.|:.:.||.|.:..
Yeast   364 PGYFADK-FIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQ 427

  Fly   544 LLGLDKLTNAFGLLLLFQGIASFIGPPIGG 573
            :.........:..:.|.|.:.:....||||
Yeast   428 ISKTTDFGKRYATVYLLQALVTIPVLPIGG 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	48/179 (27%)
		MFS	<426..604	CDD:119392	30/149 (20%)
MCH4	NP_014522.1	MFS_MCT_SLC16	96..490	CDD:340910	92/543 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343230
Domainoid	1	1.000	72	1.000	Domainoid score	I2205
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840