Protein Alignment Mct1 and MCH2

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_012701.2
• Gene: MCH2 / 853659
• SGDID: S000001704
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 593
• Identity: 110/593 - (18%)
• Similarity: 189/593 - (31%)
• Gaps: 232/593 - (39%)

  Fly    11 SQQQHEACEMDMERQPT----------------PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFY 59
            |:::||....|:|.:..                .||||:||.::....:.:..|.|....:.|:.
Yeast     2 SEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYL 66

  Fly    60 NEFLDYFNEGKGYTAWIASIMVGVTFSSG----PISSSFVNRYGCRAVTIAGSILAASCIIVSMF 120
            ..:|:......|.....||| .|:.||.|    |:.:...:.:..:.:...|.:...:.::::.|
Yeast    67 AHYLENNTFAGGSKLDYASI-GGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAF 130

  Fly   121 AQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIG 185
            :..:..:.:|.|...|.|...|::|::..:..:|..|||||:||...|||.|..||
Yeast   131 SVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVF--------- 186

  Fly   186 NYGWRGAMLIIG---GIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAEL 247
            |.|.:..:...|   .::..|||
Yeast   187 NLGMQSILQKRGVKWALIAQCII------------------------------------------ 209

  Fly   248 EPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVK 312
                                       |
Yeast   210 ---------------------------C------------------------------------- 210

  Fly   313 STSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSG 377
             ||...||      |.||  |..|:........|:.:.|         ||     |:   :|...
Yeast   211 -TSLSTIA------LMLT--RTTHQGLRQHKRSYKFELL---------DY-----DV---LSNFA 249

  Fly   378 VIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGF 442
            |...:|                                 .::|::| ..|.:::|:|:|..|:|:
Yeast   250 VWLLFG---------------------------------FVSFAML-GYVVLLYSLSDFTVSLGY 280

  Fly   443 NVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVST 507
                            |....||:...:.|.:.:||.|:|:|:||        |........:..
Yeast   281 ----------------TSKQGSYVSCMVSVGSLLGRPIVGHIADK--------YGSLTVGMILHL 321

  Fly   508 AMVPLCHDF----QSLAFYCCVFGFTIGAYVG----LTSVILVDLLGLDKLTNAFGLLLLFQGIA 564
            .|..||...    ::|| ....||..:|:.:|    ..:.|:..::||.||...||...:|....
Yeast   322 VMAILCWAMWIPCKNLA-TAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAF 385

  Fly   565 SFIGPPIG 572
            :.:.|.||
Yeast   386 ALVAPIIG 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	42/184 (23%)
		MFS	<426..604	CDD:119392	38/155 (25%)
MCH2	NP_012701.2	MFS_MCT_SLC16	41..428	CDD:340910	101/554 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1250
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm13433
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
TreeFam	1	0.960	-	-
	8	7.920