Protein Alignment Mct1 and Slc16a3

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_110461.1
• Gene: Slc16a3 / 80878
• RGDID: 620603
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 147/616 - (23%)
• Similarity: 246/616 - (39%)
• Gaps: 217/616 - (35%)

  Fly    22 MERQPT---PPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASI 79
            ::..||   .|||||||.|:||.|:|    .|.:|:|    .:|:.|.:..|..|...||||:||
  Rat     6 VDEGPTGIKAPDGGWGWAVLFGCFII----TGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSI 66

  Fly    80 MVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYL 144
            ::.:.:.:||:.|..|||:|||.|.:.|.:.|:..::.:.|.::::.:.:|.|..||||..|.:.
  Rat    67 LLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQ 131

  Fly   145 PAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAM 209
            |:::.:.:||..:|.:|.|:|..||.......:||.:.|..:|||||..||:||::|||.:..|:
  Rat   132 PSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAAL 196

  Fly   210 FRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGAL 274
            .|||                                      |.|:             .||||
  Rat   197 MRPL--------------------------------------VAPQ-------------ASGGA- 209

  Fly   275 CRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRER 339
                      :|:            ||...:|
  Rat   210 ----------EPH------------GPQRPSP--------------------------------- 219

  Fly   340 SASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCI 404
                                                                             
  Rat   220 ----------------------------------------------------------------- 219

  Fly   405 TCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLIST 469
                       .:::.|:.:|..|:|::|:.....:|..||.::||:||:.:.:..|.|::|::.
  Rat   220 -----------RLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTI 273

  Fly   470 IGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGV----------STAMVPLCHDFQSLAFYCC 524
            :|..:...|...|:|:.   :.::..|:|.|.:..:          |||     .|:..|..:|.
  Rat   274 LGFIDIFARPTAGFITG---LKKVRPYSVYLFSFAMFFNGFTDLTGSTA-----SDYGGLVVFCI 330

  Fly   525 VFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMA 589
            .||.:.|....|...:|:.::|..|.::|.||:||.:.:|..||||.||.:.|.|..|...|::|
  Rat   331 FFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILA 395

  Fly   590 GLMIAISGLVM-----FAIPPLQRLQVRKSE 615
            |..:..|.||:     |.|...:|.:|.|.|
  Rat   396 GAEVLTSSLVLLLGNFFCIGKRKRPEVTKPE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	65/181 (36%)
		MFS	<426..604	CDD:119392	55/192 (29%)
Slc16a3	NP_110461.1	MFS_MCT3_4	21..410	CDD:340988	134/583 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm12325
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.750