Protein Alignment Mct1 and Slc16a10

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001107804.1
• Gene: Slc16a10 / 72472
• MGIID: 1919722
• Length: 512
• Species: Mus musculus
• Alignment Length: 637
• Identity: 130/637 - (20%)
• Similarity: 227/637 - (35%)
• Gaps: 199/637 - (31%)

  Fly     4 GPPARRKSQQQHEACEMDMERQ-----PTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFL 63
            ||.....|....|..|:::.|.     |.||:|||||:|:..:...:....|:..::|:.:...|
Mouse    32 GPGPSDVSDVAAEKVEVELTRSAGSEPPVPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSML 96

  Fly    64 DYF----NEGKGY-TAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQN 123
            |.|    ::...: |||:.|:.:|:.|...||.|.|.:.:|||...:.|:.:....::.|.|..:
Mouse    97 DTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSS 161

  Fly   124 VLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYG 188
            :..|.:|.|.....|....|.|::|.:..||:.:..|..||...||.    ||..|...|:||.
Mouse   162 IEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSS----VFTILLPLLLGNL- 221

  Fly   189 WRGAMLIIGGIVLNCI------IFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAEL 247
             ..::.:...:.:.||      :.|..:|||           .|||.:
Mouse   222 -ISSVKLFNTLRILCIFMFVLFLAGFTYRPL-----------VPSTKE----------------- 257

  Fly   248 EPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVK 312
                   |:             |||:  ||:.....                   .::||:.|
Mouse   258 -------KE-------------SGGS--RSSFFSRR-------------------KLSPPKKV-- 279

  Fly   313 STSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSG 377
                                                                             
Mouse   280 ----------------------------------------------------------------- 279

  Fly   378 VIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGF 442
                                                    .||:|.|:..:.:::........|:
Mouse   280 ----------------------------------------FNFALFKETTYAVWAAGIPLALFGY 304

  Fly   443 NVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISD-KPWVNRLLVYNVCLTACGVS 506
            .|||::::.:.:.......:...|...||:.:.|||::.|.|:| .|.|.::.:..:.....|:.
Mouse   305 FVPYVHLMNHVKERFQDVNNKEVLFMCIGITSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLM 369

  Fly   507 TAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPI 571
            :.|:|||..|.:|...|...|...|.::.:.:.|..:|:|....:.|.|.||.|..|...:||||
Mouse   370 SMMIPLCSAFGALIAVCLAMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPI 434

  Fly   572 GGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHL 623
            .|.::|...:|..||.:||:...:.|:|:..||.:...:.||..:....|.:
Mouse   435 AGLLHDKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKM 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	47/188 (25%)
		MFS	<426..604	CDD:119392	47/178 (26%)
Slc16a10	NP_001107804.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		3/11 (27%)
		2A0113	53..484	CDD:273325	123/612 (20%)
		MFS	68..467	CDD:119392	112/580 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750