Protein Alignment Mct1 and Slc16a14

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_082197.1
• Gene: Slc16a14 / 71781
• MGIID: 1919031
• Length: 512
• Species: Mus musculus
• Alignment Length: 619
• Identity: 175/619 - (28%)
• Similarity: 278/619 - (44%)
• Gaps: 134/619 - (21%)

  Fly    15 HEACEMDME----------RQPTPP-DGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNE 68
            ||....|:|          .:|.|. ||||.|::|..||.:||:..|...:.|:...|:|:.|::
Mouse     5 HEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQ 69

  Fly    69 GKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGF 133
            .:|.|||::|:.:|:|...||....|:|..|||...|.|.::.:...::|.:|.||.:|.||.|.
Mouse    70 SRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGV 134

  Fly   134 GTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGG 198
            ..|||.|:.||||:|.|.:||:.:|:||.|::..|:|||||:...|.::|...||||.||.|.|.
Mouse   135 AAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGA 199

  Fly   199 IVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQ 263
            :.||..:.||:.|||.    |:...|.|                   |.|....||       ..
Mouse   200 LSLNLCVCGALMRPLS----PEKLENCP-------------------EAEEPCALP-------AY 234

  Fly   264 RTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQ 328
            .|::..|||.|                   |....|.           :...|:::.  |..|.|
Mouse   235 STESVKSGGPL-------------------GMAEEQD-----------RRPGNEEMV--CDLQTQ 267

  Fly   329 LTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQ 393
            ..                      ||..|...:..:.|           |:|         .|||
Mouse   268 EC----------------------QGQTHPRKNVCAFR-----------VLK---------TVSQ 290

  Fly   394 SQEEAKCCGCITCSKETRDTFAEMM-NFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLK 457
            ...:.:        :..||..:... ..||..:.:||.|..........|.:|::::........
Mouse   291 LTVQVR--------RGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYN 347

  Fly   458 LTKTDASY-LISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTA---CGVSTAMVPLCHDFQS 518
            |::.:.:: |.|.|.:.:..|::|||.::|.|.::   |:||.|.|   ..:|..::||.|.:.|
Mouse   348 LSEQNDTFPLTSIIAILHIFGKVILGAVADLPCIS---VWNVFLIANFTLVLSIFLLPLMHTYAS 409

  Fly   519 LAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYA 583
            ||..|.:.||:.| |..|..|:..||:|.:.|.||:|:::...||::.:|||..||::|:|..|.
Mouse   410 LAVICALIGFSSG-YFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYD 473

  Fly   584 PAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERK 617
            .:|.:.||:..:..|.:...|.:|  .:.:|.||
Mouse   474 FSFYICGLLYMVGILFLLIQPCIQ--MIDQSRRK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	72/177 (41%)
		MFS	<426..604	CDD:119392	55/181 (30%)
Slc16a14	NP_082197.1	MFS_MCT14	35..494	CDD:340987	160/574 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm11108
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740