Protein Alignment Mct1 and Slc16a13

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_758959.1
• Gene: Slc16a13 / 69309
• MGIID: 1916559
• Length: 428
• Species: Mus musculus
• Alignment Length: 619
• Identity: 149/619 - (24%)
• Similarity: 240/619 - (38%)
• Gaps: 211/619 - (34%)

  Fly    22 MERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFS 86
            |.|:..||||||||:||..:|....:..|:..|||:|:.||:..|.|.....:|||||.:.|...
Mouse     1 MVRRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQF 65

  Fly    87 SGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVT 151
            ..||.|:...:.|.|.|.:.|.||||..::::.||.::..|.::||..:|.|:.|.:.|.:..::
Mouse    66 GSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTMACLS 130

  Fly   152 QYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELE 216
            :||..:||||.|:|:.|.|..:|.||||.::||.||.||||:|::..:.|:.:..||:.|||.|
Mouse   131 RYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSL- 194

  Fly   217 APPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVG 281
                                                            |:.|..||
Mouse   195 ------------------------------------------------TEDAAVGG--------- 202

  Fly   282 HNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMY 346
                                     |.|                  |:|
Mouse   203 -------------------------PGA------------------QIT---------------- 208

  Fly   347 RPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETR 411
                                                                             
Mouse   209 ----------------------------------------------------------------- 208

  Fly   412 DTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTV 476
                     |||:...|:.::.:....:.||.:||:::||:.:.|......|::|:|...|::.|
Mouse   209 ---------SLLRHGPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAFLLSVAAVSDLV 264

  Fly   477 GRIILGYISDK---PWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTS 538
            ||:..|::.|.   | |.|||:....||  |||.|:.|:.....:|......:|||.||...:..
Mouse   265 GRVASGWLGDAVPGP-VARLLMLWTTLT--GVSLALFPVAQASSTLVVLAVAYGFTSGALTPVAF 326

  Fly   539 VILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAI 603
            .:|.:|:|..::....||:.:.:.|...:|.|:.|::.|:|.:|..:|::||..:.....|:..:
Mouse   327 SVLPELVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTL 391

  Fly   604 PPL-----------QRLQVRKSERK---PHTEHL 623
            |..           |.|.:..|:.|   |..|.|
Mouse   392 PHFFSCISVSTSRPQDLVIEASDTKIPLPKEEGL 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	133/572 (23%)
Slc16a13	NP_758959.1	MFS_MCT11_13	13..392	CDD:340981	133/572 (23%)