Protein Alignment Mct1 and Slc16a9

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001408038.1
• Gene: Slc16a9 / 687808
• RGDID: 1596295
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 171/598 - (28%)
• Similarity: 257/598 - (42%)
• Gaps: 130/598 - (21%)

  Fly    29 PDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSS 93
            ||||||||:|..||....:..|...:.|:.|.|:||.|.||||.|||:.|:..||...:.|:.|.
  Rat     7 PDGGWGWVIVVVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSL 71

  Fly    94 FVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKR 158
            ||:.:|.|.|||....|.|..:::|..|.|:..|..:.|...|||.||:|...:....|||:::|
  Rat    72 FVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRR 136

  Fly   159 SLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPP 223
            .||.|:...||..|.|::|.|...||..||..|.:||:|.:.||.:..|::.|||:....|
  Rat   137 GLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCP---- 197

  Fly   224 NTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNL 288
                                    .|.|:.|::    :|.|                 :::....
  Rat   198 ------------------------FPEKIAPEN----VPDR-----------------YSIYNEK 217

  Fly   289 NNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQ 353
            ..|....:..|.           |..||:|   ||      .|..|..||.|
  Rat   218 EKNQEETMTFQD-----------KGYSNED---KC------LPNGDWGRETS------------- 249

  Fly   354 GSLHNLPDYVSSRNDLSRSMSGSGVIK-----RYGSLRQSNNVSQS-----QEEAKCCGCITCSK 408
                           |.::.:|:...|     :...:.|:|...|.     |.....||
  Rat   250 ---------------LPKNPTGAAHTKEPEPYKKKVVEQTNFCKQLAKRKWQVYRNYCG------ 293

  Fly   409 ETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASY-LISTIGV 472
            ||.         ||.|:.||....|:.....||...|.|.:...|.:..:.:.|.:. |||..|:
  Rat   294 ETA---------SLFKNKVFSALFVAILLFDIGGFPPSLLMEDVARSYHVREEDLTIPLISIFGI 349

  Fly   473 ANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLT 537
            ...||:::||.::|..|||.|.:|...|...|::...:||...:.:||....:.||..|.: .:.
  Rat   350 MTAVGKLLLGILADFKWVNTLYLYVATLIITGLALCAIPLAKSYVTLAILSGILGFLTGNW-SIF 413

  Fly   538 SVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISG-LVMF 601
            ..:....:|:|||.:|:|:|:.|.|:.:.:||||.||.||.|.:|..||..:|..:.:.| :::.
  Rat   414 PYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 478

  Fly   602 AIPPL-----QRL 609
            ||.|.     |||
  Rat   479 AILPCWGMCNQRL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	161/581 (28%)
Slc16a9	NP_001408038.1	MFS_MCT9	12..479	CDD:340986	160/579 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..263		7/48 (15%)