Protein Alignment Mct1 and Slc16a8

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_113932.2
• Gene: Slc16a8 / 65200
• RGDID: 69282
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 597
• Identity: 141/597 - (23%)
• Similarity: 227/597 - (38%)
• Gaps: 208/597 - (34%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSG 88
            ||||||||||:...|:|    .|..|.|    .:|:.|....|..|...|||::|||:.:.:.:|
  Rat    12 PPDGGWGWVVLGACFVI----TGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTG 72

  Fly    89 PISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQY 153
            |:||..|.|:|||.|.:||.:||::.:|::.||..:|.|.:|.|..||||..|.:.|:::.:..|
  Rat    73 PLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLY 137

  Fly   154 FEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAP 218
            ||.:|.||.|:|..||.......:||.:.|...:||||..|:.||::|:|...||:.||     |
  Rat   138 FERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRP-----P 197

  Fly   219 PQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHN 283
            |...|                                        |.|.|..||
  Rat   198 PGPQP----------------------------------------RPDPAPPGG----------- 211

  Fly   284 LKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRP 348
                                                             |..||
  Rat   212 -------------------------------------------------RARHR----------- 216

  Fly   349 DALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDT 413
                                                                             
  Rat   217 ----------------------------------------------------------------- 216

  Fly   414 FAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGR 478
              ::::.::..|..|:::.|:.|..::|..||.:.:|.||:...:...:|::|:|.:|..:.|.|
  Rat   217 --QLLDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVAR 279

  Fly   479 IILGYISD----KPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSV 539
            ...|.::.    :|.|..|  :::.|.|.|::..:......:.:|..:|..||.:.|....|...
  Rat   280 PACGALAGLGRLRPHVPYL--FSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFE 342

  Fly   540 ILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFA-- 602
            :|:..:|..:..:|.||:||.:.:|..||||..|.:.|...:|...|.:||..:.::|:.|..
  Rat   343 VLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVVLAGVFMAVTT 407

  Fly   603 ---------IPP 605
                     |||
  Rat   408 YCCQRCSKDIPP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	70/181 (39%)
		MFS	<426..604	CDD:119392	48/192 (25%)
Slc16a8	NP_113932.2	2A0113	14..440	CDD:273325	139/595 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339262
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850