Protein Alignment Mct1 and slc16a7

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001032485.1
• Gene: slc16a7 / 641419
• ZFINID: ZDB-GENE-051113-248
• Length: 465
• Species: Danio rerio
• Alignment Length: 605
• Identity: 137/605 - (22%)
• Similarity: 235/605 - (38%)
• Gaps: 180/605 - (29%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||||||||.||||||    ::.|.:|:|    .|::.|..:||:......||::|||:...::.
Zfish    12 TPPDGGWGWAVVFGSF----ISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQ 152
            ||:||..|||||.|.|.|||.::....::.:.|..::|.|.:.:|...|.|......||:..:.:
Zfish    73 GPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFDLQPALTIIGK 137

  Fly   153 YFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            ||..||.:|.|||:.||.......||:.:||...:||||:..|:||::.||.:.|::.||:::.
Zfish   138 YFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPIKIP- 201

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
                                                                             
Zfish   202 ----------------------------------------------------------------- 201

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
                                        |..|:.|:|:.:
Zfish   202 ----------------------------VSKTTEDNISPQ------------------------- 213

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
                                                        :..|:::|..||  .||
Zfish   214 --------------------------------------------TAGQDDSKPSGC--SSK---- 228

  Fly   413 TFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVG 477
             ..:.::.||.|...|:|:.|.|.....||..|.:::..||:...:.:..|::|:|...:.:...
Zfish   229 -LNQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFALVDMFA 292

  Fly   478 RIILGYISDKPWVNRLLVY--NVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVI 540
            |...|.:::..|:...:.|  :..:|..|:...|.||...:..|..|..:||...|....|...:
Zfish   293 RPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIGLVVYAVLFGLAFGMVCALLFEV 357

  Fly   541 LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPP 605
            |:||:|..:.::|.||..:.:.....:||||.|.:.|:...|...:...|:|:...|:.:|.:..
Zfish   358 LMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVFLFIMNY 422

  Fly   606 LQRLQVRKSERKPHTEHLAL 625
            .....::|.|::.:.|.|.:
Zfish   423 YNYRWLKKEEKQRNAEELQI 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	66/181 (36%)
		MFS	<426..604	CDD:119392	45/179 (25%)
slc16a7	NP_001032485.1	2A0113	1..440	CDD:273325	136/601 (23%)
		MFS	20..420	CDD:119392	125/573 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578886
Domainoid	1	1.000	142	1.000	Domainoid score	I4621
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.850