Protein Alignment Mct1 and slc16a7

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001032485.2
• Gene: slc16a7 / 641419
• ZFINID: ZDB-GENE-051113-248
• Length: 465
• Species: Danio rerio
• Alignment Length: 607
• Identity: 141/607 - (23%)
• Similarity: 238/607 - (39%)
• Gaps: 184/607 - (30%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||||||||.||||||    ::.|.:|:|    .|::.|..:||:......||::|||:...::.
Zfish    12 TPPDGGWGWAVVFGSF----ISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGF--GTGLGFGLIYLPAIVSV 150
            ||:||..|||||.|.|.|||.::....::.:.|..::|.|.:.:|.  |.||.|.|  .||:..:
Zfish    73 GPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFNL--QPALTII 135

  Fly   151 TQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLEL 215
            .:||..||.:|.|||:.||.......||:.:||...:||||:..|:||::.||.:.|::.||:::
Zfish   136 GKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPIKI 200

  Fly   216 EAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSV 280
            .
Zfish   201 P---------------------------------------------------------------- 201

  Fly   281 GHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTM 345
                                          |..|:.|:|:.:
Zfish   202 ------------------------------VSKTTEDNISPQ----------------------- 213

  Fly   346 YRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKET 410
                                                          :..|:|:|..||  .||
Zfish   214 ----------------------------------------------TAGQDESKPSGC--SSK-- 228

  Fly   411 RDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANT 475
               ..:.::.||.|...|:|:.|.|.....||..|.:::..||:...:.:..|::|:|...:.:.
Zfish   229 ---LNQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFALVDM 290

  Fly   476 VGRIILGYISDKPWVNRLLVY--NVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTS 538
            ..|...|.:::..|:...:.|  :..:|..|:...|.||...:..|..|..:||...|....|..
Zfish   291 FARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIDLVVYAVLFGLAFGMVCALLF 355

  Fly   539 VILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAI 603
            .:|:||:|..:.::|.||..:.:.....:||||.|.:.|:...|...:...|:|:...|:.:|.:
Zfish   356 EVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVFLFIM 420

  Fly   604 PPLQRLQVRKSERKPHTEHLAL 625
            .......::|.|::.:.|.|.:
Zfish   421 NYYNYRWLKKEEKQRNAEELQI 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	130/577 (23%)
slc16a7	NP_001032485.2	2A0113	1..440	CDD:273325	140/603 (23%)