Protein Alignment Mct1 and Slc16a8

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_065262.1
• Gene: Slc16a8 / 57274
• MGIID: 1929519
• Length: 492
• Species: Mus musculus
• Alignment Length: 581
• Identity: 139/581 - (23%)
• Similarity: 225/581 - (38%)
• Gaps: 197/581 - (33%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSG 88
            ||||||||||:...|    |..|..|.|    .:|:.|....|..|...|||::|||:.:.:.:|
Mouse    12 PPDGGWGWVVLGACF----VVTGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTG 72

  Fly    89 PISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQY 153
            |:||..|.|:|||.|.:||.:||::.:|::.||..::.|.:|.|..||||..|.:.|:::.:..|
Mouse    73 PLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLY 137

  Fly   154 FEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAP 218
            ||.:|.||.|:|..||.....:.:||.:.|...:||||..|:.||::|:|...||:.||     |
Mouse   138 FERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRP-----P 197

  Fly   219 PQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHN 283
            |..||                                        |.|.:..||
Mouse   198 PGPPP----------------------------------------RRDPSPHGG----------- 211

  Fly   284 LKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRP 348
                                                              .|.|.|
Mouse   212 --------------------------------------------------PARRRR--------- 217

  Fly   349 DALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDT 413
                                                                             
Mouse   218 ----------------------------------------------------------------- 217

  Fly   414 FAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGR 478
               :::.::..|..||::.|:.|..::|..||.:.:|.||:...:...:|::|:|.:|..:.|.|
Mouse   218 ---LLDVAVCTDRAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVAR 279

  Fly   479 IILGYISD----KPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSV 539
            ...|.::.    :|.|..|  :::.|.|.|::..:......:.:|..:|..||.:.|....|...
Mouse   280 PACGALAGLGRLRPHVPYL--FSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFE 342

  Fly   540 ILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVM 600
            :|:..:|..:..:|.||:||.:.:|..||||..|.:.|...:|...|.:||..:|::|:.|
Mouse   343 VLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVALAGVFM 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	69/181 (38%)
		MFS	<426..604	CDD:119392	50/179 (28%)
Slc16a8	NP_065262.1	2A0113	14..440	CDD:273325	137/579 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850