Protein Alignment Mct1 and slc16a4

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001074068.2
• Gene: slc16a4 / 567144
• ZFINID: ZDB-GENE-070112-602
• Length: 558
• Species: Danio rerio
• Alignment Length: 605
• Identity: 173/605 - (28%)
• Similarity: 274/605 - (45%)
• Gaps: 103/605 - (17%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISS 92
            ||||||||:||...|:::::..|...:||||:....|.|.......:||.|||..:..|.||::|
Zfish    37 PPDGGWGWMVVLHCFLVNVLVMGTLKTFGIFFVALQDEFGGSSESISWIGSIMSSLRLSGGPLAS 101

  Fly    93 SFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAK 157
            ....:.|.|..:|.|::..::..:.|:||.:|..|.|::|...||||.|:|....|.:..||  :
Zfish   102 VACAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLGFALLYQATSVVIVTYF--R 164

  Fly   158 RSLATGIAVCGSGFG-TFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQT 221
            :.|||..::..||.| ||..||.|:.|:..|.|:||:||:||::||.:..|.:.||:.:..|
Zfish   165 KRLATAYSIGRSGMGLTFALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPINIRHP--- 226

  Fly   222 PPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKP 286
                        .|.|.:......|.:|||
Zfish   227 ------------ASPISNSTIHKTEKDPLK----------------------------------- 244

  Fly   287 NLNNNSNG---AVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHR--ERSASGTMY 346
               ||.||   ..||...:..:||  :.|.|.  .|....|.|..| |..|..:  :...:||
Zfish   245 ---NNMNGNTPVANGTSKSDSSPP--IHKDTL--IIKNPVHEQNSL-PHLDLKKPTQNGVNGT-- 299

  Fly   347 RPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETR 411
                            .||:...|..|:|   :....||.::.......|.:
Zfish   300 ----------------DSSQTKTSPEMNG---VSPVDSLLENGRTENVPENS------------- 332

  Fly   412 DTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTV 476
               .::::|||||:..|.|::.|...:.:.:.:||.::.|.|..|.:...|||::||..|:..||
Zfish   333 ---PKVLDFSLLKNPFFCIYTWSLVFSQLAYFIPYFHLSARARNLGIDPMDASFIISVAGITETV 394

  Fly   477 GRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVIL 541
            .::..|:::|:..|::...:...|..|||...:.||...:..|..|...|....|.|:.|...:|
Zfish   395 AQLASGWVTDRNLVHKYHYHKAYLILCGVVNLLSPLATSYILLMVYAVFFAIFCGGYMALLLPVL 459

  Fly   542 VDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPL 606
            |||:|.|||.|:.|..:.|.|:....|||:.|::||.|.:|..:|.:||:...:|.:.:|..|..
Zfish   460 VDLVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQTYDCSFYLAGVCYLLSSISLFLEPLA 524

  Fly   607 QRLQVRKSERKPHTEHLALS 626
            :|.|.||...:...:.|..|
Zfish   525 RRWQARKERLETLNQELMWS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	64/178 (36%)
		MFS	<426..604	CDD:119392	56/177 (32%)
slc16a4	NP_001074068.2	2A0113	35..520	CDD:273325	165/579 (28%)
		MFS	47..520	CDD:119392	156/569 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578916
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2778
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109218
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900