Protein Alignment Mct1 and slc16a6a

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001243761.1
• Gene: slc16a6a / 564872
• ZFINID: ZDB-GENE-110208-1
• Length: 495
• Species: Danio rerio
• Alignment Length: 582
• Identity: 133/582 - (22%)
• Similarity: 240/582 - (41%)
• Gaps: 142/582 - (24%)

  Fly    29 PDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSS 93
            |||||||:|....|::.:.|.|:..|||||..:.:..|||.....:||.||.|.|...:.|:|:.
Zfish    21 PDGGWGWIVAVALFLVEVFTYGVIKSFGIFLKDLMSDFNETNSRVSWIISICVFVMTFTAPLSTM 85

  Fly    94 FVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKR 158
            ..||:|.:.|.:.|..|.:...|.:.|..::..:.:|||..||||:.|.:||....::|||..:|
Zfish    86 LSNRFGFQPVVMFGGFLISLGTISTAFTSSINQMYLTIGIATGLGYCLTFLPTATILSQYFSRRR 150

  Fly   159 SLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPP 223
            |:...:|..|..|.||.|||....|....|.|..:::||.:....||.||:.||:.::
Zfish   151 SVVMAMASTGESFATFAFAPAFTALKNYIGRRYTLVVIGTLQGITIICGALLRPIVIK------- 208

  Fly   224 NTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNL 288
              |:             :.|..|.:....||.:|
Zfish   209 --PT-------------SLTETEQKITYTLPVEQ------------------------------- 227

  Fly   289 NNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQ 353
                   |.|.|             :|.|.:.:....:                          |
Zfish   228 -------VQGFG-------------SSGDSVVQSLEQE--------------------------Q 246

  Fly   354 GSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMM 418
            |              |...:....|.....:|:|.:|.|:::                     ::
Zfish   247 G--------------LKSGIELEEVEPVQINLKQQDNTSKNR---------------------LL 276

  Fly   419 NFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGY 483
            :.::||:..|:.:|......::||..|.||||..:.:|...:..|:|::|.:.::..:||:.:|:
Zfish   277 DLTVLKEGSFLCYSAFGLFATLGFFAPQLYVVELSASLGTERDKAAYMLSIMAISEIIGRLSIGW 341

  Fly   484 ISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILV-----D 543
            :.:...:.::.|..:|::...:...:..:.:.|..|...|.::||.:|   .:||..:.     |
Zfish   342 VMNCGCIRKIFVLLICVSLMCLVLVLFTIVNGFWGLVVCCVLYGFLLG---NITSTHIPMLAEDD 403

  Fly   544 LLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPP 605
            ::|:.::..|.|:.:..|..|...|||:||.:.|:|.:|:.||......:.:..:.:..:.|
Zfish   404 VVGIQRMPLAVGVYVCIQSFAGLAGPPLGGVLVDITQNYSAAFYSCAAGMGLGAIFLGLVRP 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	62/177 (35%)
		MFS	<426..604	CDD:119392	42/182 (23%)
slc16a6a	NP_001243761.1	MFS	31..464	CDD:119392	124/569 (22%)
		MFS_1	33..429	CDD:284993	114/532 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578900
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950