Protein Alignment Mct1 and slc16a12a

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_009291327.2
• Gene: slc16a12a / 557762
• ZFINID: ZDB-GENE-080721-24
• Length: 617
• Species: Danio rerio
• Alignment Length: 629
• Identity: 179/629 - (28%)
• Similarity: 304/629 - (48%)
• Gaps: 73/629 - (11%)

  Fly     6 PAR--RKSQQQHEACE----------MDM-ERQP---TPPDGGWGWVVVFGSFMIHIVTDGMTYS 54
            ||.  :|.:|:.|..|          ::| |:.|   |.|||||||::|.|.|:..:.|..:|..
Zfish    27 PAETGQKRKQEAERSEGMKERMKRGRLEMCEKNPCLATAPDGGWGWMIVAGCFLTTVCTRAVTRC 91

  Fly    55 FGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSM 119
            ..||:.||..||:.....||||.|::...|....|:.|...||...|...:.|.:|:::.:::|.
Zfish    92 VSIFFVEFQLYFSRDYSATAWIHSLLDCTTMLCAPLGSYIGNRLSSRIAIMIGGLLSSTGLLLSS 156

  Fly   120 FAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLI 184
            .|.:|..|.:|:|..||:||.|.|.|||..|..||..:::||.|||:.|||.|||:.||..:.||
Zfish   157 LATSVEFLYLTLGVLTGVGFALSYTPAIAMVGSYFRQRKALAYGIAMSGSGIGTFILAPAVQLLI 221

  Fly   185 GNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTP---PNTPSTPKLAKKSAIID-----QN 241
            ..:.||||:||:.|:|.:....||:.|||:.:...|..   .|..:...|..|.|.::     :.
Zfish   222 EFFSWRGALLILAGLVSHLCFCGALMRPLQSQRGRQNKMDLENGKTVDLLNVKLAYVELRGSMEV 286

  Fly   242 TTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTP 306
            |.|...|..|..|.:..|:         :|.....::.:..:   :|:...|     .|..|...
Zfish   287 THAVVKEMEKKEPSENMLR---------NGKGWIEADDMKQS---HLDEEEN-----HGQDLSEN 334

  Fly   307 PQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSR 371
            |:.|.|.:..:.......:.:|            :||........||.:: ..|:..|..|:...
Zfish   335 PKTVNKWSEEEPRTISIPALVQ------------SSGLPLENLLKYQKNI-TFPESKSEGNNNQS 386

  Fly   372 SMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNF 436
            :::.|.|:|       :..:.:|:|..        ....|.|..:..:|.|:.|  |::..||..
Zfish   387 TVAKSKVVK-------AKLLKESKENV--------WSVLRKTVLKEYSFLLIPD--FLLLLVSFL 434

  Fly   437 CTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVN--RLLVYNVC 499
            ..:.|.:||::|:|.|:.:..::...|:.::|.:||:..:|.|..|:|:|:..:.  |::.|.:.
Zfish   435 FLAYGCSVPFVYLVPYSLSAGVSPQQAALVMSILGVSGIIGTITFGWIADRKCLRPYRVVSYMLA 499

  Fly   500 LTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIA 564
            :.:.|:|...:||...|..|..:..::|:..||||.|..|:..|.:...:||:|.|::.....|.
Zfish   500 VGSEGLSCLFLPLLSGFSLLVPFSLIYGYFDGAYVALIPVVTSDTVSSAQLTSALGVVYFLHAIP 564

  Fly   565 SFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQR 608
            ..|.||||||:.|.|.||...|:::|:.:..|.:::.|:..:.|
Zfish   565 YLISPPIGGWLVDQTGSYTATFILSGVSLICSAVILAAVKVIFR 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	163/579 (28%)
slc16a12a	XP_009291327.2	None