Protein Alignment Mct1 and slc16a12a

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_009291327.1
• Gene: slc16a12a / 557762
• ZFINID: ZDB-GENE-080721-24
• Length: 617
• Species: Danio rerio
• Alignment Length: 629
• Identity: 178/629 - (28%)
• Similarity: 300/629 - (47%)
• Gaps: 73/629 - (11%)

  Fly     6 PAR--RKSQQQHEACE----------MDM-ERQP---TPPDGGWGWVVVFGSFMIHIVTDGMTYS 54
            ||.  :|.:|:.|..|          ::| |:.|   |.|||||||::|.|.|:..:.|..:|..
Zfish    27 PAETGQKRKQEAERSEGMKERMKRGRLEMGEKNPCLATAPDGGWGWMIVAGCFLTTVCTRAVTRC 91

  Fly    55 FGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSM 119
            ..||:.||..||:.....||||.|::...|....|:.|...||...|...:.|.:|:::.:::|.
Zfish    92 VSIFFVEFQLYFSRDYSATAWIHSLLDCTTMLCAPLGSYIGNRLSSRIAIMIGGLLSSTGLLLSS 156

  Fly   120 FAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLI 184
            .|.:|..|.:|:|..||:||.|.|.|||..|..||..:::||.|||:.|||.|||:.||..:.||
Zfish   157 LATSVEFLYLTLGVLTGVGFALSYTPAIAMVGSYFRQRKALAYGIAMSGSGIGTFILAPAVQLLI 221

  Fly   185 GNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTP---PNTPSTPKLAKKSAIID-----QN 241
            ..:.||||:||:.|:|.:..:.||:.|||:.:...|..   .|..:...|..|.|.::     :.
Zfish   222 EFFSWRGALLILAGLVSHLCVCGALMRPLQSQRGRQNKMDLENGKTVDLLNVKLAYVELRGSMEV 286

  Fly   242 TTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTP 306
            |.|...|..|..|.:..|:                 |..|.....::..:........|..|...
Zfish   287 THAVVKEMEKKEPSENMLR-----------------NGKGWIEADDMKQSHLDGEENHGQDLSEN 334

  Fly   307 PQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSR 371
            |:.|.|.:..:.......:.:|            :||........||.:: ..|:..|..|:...
Zfish   335 PKTVNKWSEEEPRTISIPALVQ------------SSGLPLENLLKYQKNI-TFPESKSEGNNNQS 386

  Fly   372 SMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNF 436
            :::.|.|:|       :..:.:|:|..        ....|.|..:..:|.|:.|  |::..||..
Zfish   387 TVAKSKVVK-------AKLLKESKENV--------WSVLRKTVLKEYSFLLIPD--FLLLLVSFL 434

  Fly   437 CTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVN--RLLVYNVC 499
            ..:.|.:||::|:|.|:.:..::...|:.::|.:||:..:|.|..|:|:|:..:.  |::.|.:.
Zfish   435 FLAYGCSVPFVYLVPYSLSAGVSPQQAALVMSILGVSGIIGTITFGWIADRKCLRPYRVVSYMLA 499

  Fly   500 LTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIA 564
            :.:.|:|...:||...|..|..:..::|:..||||.|..|:..|.:...:||:|.|::.....|.
Zfish   500 VGSEGLSCLFLPLLSGFSLLVPFSLIYGYFDGAYVALIPVVTSDTVSSAQLTSALGVVYFLHAIP 564

  Fly   565 SFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQR 608
            ..|.||||||:.|.|.||...|:::|:.:..|.:::.|:..:.|
Zfish   565 YLISPPIGGWLVDQTGSYTATFILSGVSLICSAVILAAVKVIFR 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	69/177 (39%)
		MFS	<426..604	CDD:119392	54/179 (30%)
slc16a12a	XP_009291327.1	2A0113	55..601	CDD:273325	170/592 (29%)
		MFS	75..604	CDD:119392	160/575 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578905
Domainoid	1	1.000	104	1.000	Domainoid score	I6633
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	1	0.900	-	-		OOG6_109218
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.750