Protein Alignment Mct1 and slc16a1

DIOPT Version :10

• Sequence 1: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001015931.1
• Gene: slc16a1 / 548685
• XenbaseID: XB-GENE-1014566
• Length: 490
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 141/607 - (23%)
• Similarity: 241/607 - (39%)
• Gaps: 171/607 - (28%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||:||||||||..:|    |:.|.:|:|    .:|:.:....|.......:||:|||:.|.::.
 Frog    12 TPPEGGWGWVVVVAAF----VSIGFSYAFPKSITVFFKDIEAIFGATSSEVSWISSIMLAVMYAG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQ 152
            |||||..||:||.|.|.|||..||.:.:|.:.|...|..|.:.||...|.|......||:..:.:
 Frog    73 GPISSVLVNKYGSRPVMIAGGCLAGTGLIAASFCNTVAELYLCIGVVGGFGLAFNLNPALTMIGK 137

  Fly   153 YFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            ||..||.:|.|:|:.||.......|||.::....:||||:.||:||::.||.:.|::.||:
 Frog   138 YFFKKRPIANGLAMAGSPVFLSTLAPLNQYFYSIFGWRGSFLILGGLLFNCCVAGSLMRPI---- 198

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
                .|....|.|...|..:
 Frog   199 ----GPKPEDTKKKVTKEVL--------------------------------------------- 214

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
                                               :.|.||.|:..    .|||::
 Frog   215 -----------------------------------EEAGKCVSKED----GDAHKD--------- 231

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
               |.:|.....|                       :|.|:.|
 Frog   232 ---LIEGKAKTKP-----------------------TLFQTIN---------------------- 248

  Fly   413 TFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVG 477
               :.::.||.....|:::...:.....|...|.:::..||::..::...|::|:|.:.:.:.:.
 Frog   249 ---KFLDLSLFTHRGFLLYLSGHMIMFFGLFAPLVFLSNYAKSKNISPESAAFLLSILAIVDMIA 310

  Fly   478 RIILGYISDKPWVNRLLVY--NVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVI 540
            |..:|.:::..||...:.|  .|.:...|:...:|||...:.....|...|||..|   .|:||:
 Frog   311 RPSMGIVANTKWVRPKIQYFFAVAVLYNGICHLLVPLSTSYVGFCIYAGFFGFAFG---WLSSVL 372

  Fly   541 ---LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFA 602
               |:||:|..:.::|.||:.:.:.....:|||:.|.:.|:...|...:...|:::.::.:.:|.
 Frog   373 FETLMDLVGAQRFSSAVGLVTIVECCPVLLGPPLLGRLNDIYGDYKYTYQACGIVLIVASVYLFI 437

  Fly   603 IPPLQ-RL--QVRKSERKPHTE 621
            ...:. ||  :.:|:|:|...|
 Frog   438 GMTIHYRLLAKEQKAEQKKAQE 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	129/578 (22%)
slc16a1	NP_001015931.1	2A0113	6..471	CDD:273325	141/607 (23%)