Protein Alignment Mct1 and slc16a9b

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001003552.1
• Gene: slc16a9b / 445158
• ZFINID: ZDB-GENE-040801-69
• Length: 486
• Species: Danio rerio
• Alignment Length: 580
• Identity: 156/580 - (26%)
• Similarity: 245/580 - (42%)
• Gaps: 142/580 - (24%)

  Fly    29 PDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSS 93
            |||||||.:|..|||...:..|...|.|:.|.|:|:.|.:.||.|||:.|::.||...:.||.|:
Zfish    10 PDGGWGWAIVVASFMGQFLAYGSPQSVGVLYPEWLNTFQDSKGMTAWVGSLVSGVGLIASPICSA 74

  Fly    94 FVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKR 158
            .|..:|.|.|||...::.:..:::|.||.||..||.:.|...|||.||:|...:....|||:.:|
Zfish    75 CVVNFGARPVTIFSGVMVSGGLMLSAFAPNVQFLIFSYGIVVGLGCGLVYAATVTITCQYFDKRR 139

  Fly   159 SLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPP 223
            .||.||...|:..|.|::|......|..:|..|.:|:||...||.|....:.|||.|.|
Zfish   140 GLALGIVTTGTSVGGFLYAAAQNEFIALFGLDGCLLLIGCFALNIIACAGLMRPLHLPA------ 198

  Fly   224 NTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNL 288
                        ..:.|....||.....||.|...::.|
Zfish   199 ------------YYLKQRAAMAEKAEENVLEKSPVVEDP-------------------------- 225

  Fly   289 NNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQ 353
                           |...|::|..|.:               .:|.|.:|
Zfish   226 ---------------VKKTQSIVLITGD---------------TKDTHEKR-------------- 246

  Fly   354 GSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMM 418
                .|.:||:    |.|.|                                  |:.:..::|.:
Zfish   247 ----KLLNYVT----LVRLM----------------------------------KKKQKQYSEYL 269

  Fly   419 NF--SLLKDMVFVIFSVSNFCTSIGFNVPYLYV--VAYAETLKLTKTDASYLISTIGVANTVGRI 479
            :.  .:|::.||:...||.|...:|...|.|::  :|.:|.| :|......|:|.:.:|..||::
Zfish   270 HSIGQVLQNRVFLATCVSLFAYCLGAYTPLLFLEDLAQSEGL-ITGISTIPLVSIMSIAAGVGKL 333

  Fly   480 ILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVI---L 541
            :||.:.|..|:|.:.:|.|.|...|::..::|:..::..|.....|.||    :.|..|||   .
Zfish   334 LLGVMMDVRWMNSIYLYAVTLLGTGMALLIIPVTKNYAGLQVISAVLGF----FSGNWSVIPYMT 394

  Fly   542 VDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMF 601
            ..::|:|:||.|:|:|:.|.|.:..:|||:.||:||...||..||..:|..:.:.|..:|
Zfish   395 TKVVGMDRLTEAYGILMFFGGFSIMLGPPVAGWIYDWMHSYDLAFYFSGGFVLLGGAGLF 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	65/177 (37%)
		MFS	<426..604	CDD:119392	58/181 (32%)
slc16a9b	NP_001003552.1	2A0113	8..474	CDD:273325	156/580 (27%)
		MFS	19..455	CDD:119392	149/571 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850