Protein Alignment Mct1 and slc16a12

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_989310.1
• Gene: slc16a12 / 394932
• XenbaseID: XB-GENE-1012784
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 154/589 - (26%)
• Similarity: 245/589 - (41%)
• Gaps: 163/589 - (27%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISS 92
            ||||||||::|.|.|.:.:.|..:|....||:.||..||.:....||||.||:...|....||.|
 Frog    12 PPDGGWGWMIVIGCFFVTVCTRAVTRCISIFFVEFQSYFAQDYARTAWIHSIVDCSTMLCAPIGS 76

  Fly    93 SFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAK 157
            ...|.:.|:...|.|.:||::.:::|.||.::..|.:|:|..|||||.|.|.|||..|.:|||.:
 Frog    77 YVSNHFSCQVGIILGGVLASTGLVLSSFATSLEYLYLTLGVLTGLGFALCYSPAIAMVGKYFEKR 141

  Fly   158 RSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTP 222
            ::||.|||:.|||.|||:.||:.:.||..:.||||:||:||.|.|..:.||:.||:.|
 Frog   142 KALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVSNLCVCGALMRPITL------- 199

  Fly   223 PNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPN 287
                                            |:..|..|
 Frog   200 --------------------------------KEDSLHYP------------------------- 207

  Fly   288 LNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALY 352
                                                                           |.
 Frog   208 ---------------------------------------------------------------LK 209

  Fly   353 QGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCG--CITCSKETRDTFA 415
            |..:.|.|                         .||..:..|      |.  |..||.: |..:.
 Frog   210 QEQMENEP-------------------------TQSGRLDSS------CSPLCQDCSHK-RLCYC 242

  Fly   416 EMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRII 480
            ....:|.|....|::.:||....:.|.:.|::|:|.||..:.::..:|::|:|.:|:.:.||.|.
 Frog   243 TKKEYSFLLKPKFMVLAVSFLFLAYGCSPPFVYLVPYALNVGVSNQEAAFLMSILGIIDIVGNIT 307

  Fly   481 LGYISDKPWV--NRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVD 543
            .|:::|..::  :|...|.:.:...|:....:|:...||.|..:..:||:..||||.|..|:..|
 Frog   308 FGWVTDTRFLKKHRYCCYLIAVGLDGLCCLFLPILTRFQLLVPFSVMFGYFDGAYVALIPVVTGD 372

  Fly   544 LLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQR 608
            ::|...|::|.|::.....:...:.|||.||:.|.|..|..|||::|..:....:::.....:.|
 Frog   373 VVGTSSLSSALGVVFFLHAVPYLVSPPIAGWLVDTTGDYTAAFLLSGFSMIFCAVLLALAKIINR 437

  Fly   609 LQVR 612
            ::.|
 Frog   438 IKKR 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	76/177 (43%)
		MFS	<426..604	CDD:119392	50/179 (28%)
slc16a12	NP_989310.1	2A0111	12..444	CDD:331689	154/589 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	93	1.000	Domainoid score	I7419
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H130007
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9525
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2106
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.950