Protein Alignment Mct1 and slc16a1b

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_956379.1
• Gene: slc16a1b / 368274
• ZFINID: ZDB-GENE-030515-5
• Length: 461
• Species: Danio rerio
• Alignment Length: 584
• Identity: 131/584 - (22%)
• Similarity: 221/584 - (37%)
• Gaps: 190/584 - (32%)

  Fly    27 TPPDGGWGWVVVFGSFMIHIVTDGMTYSF----GIFYNEFLDYFNEGKGYTAWIASIMVGVTFSS 87
            |||:|||||.||.|:|    ::.|.:|:|    .:|:.|....||......:||:|||:.|.::.
Zfish    12 TPPEGGWGWAVVVGAF----ISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMYAG 72

  Fly    88 GPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQ 152
            |||||..||::|.|.:.|||..|:.:.::.:.|...|..|...:|...|||......||:..:.:
Zfish    73 GPISSILVNKFGSRPIMIAGGCLSGTGLVAASFCDTVEGLYFCVGVIGGLGLAFNLNPALTMIGK 137

  Fly   153 YFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEA 217
            ||..:|.:|.|||:.||.......|||..:|...:||||:.||:||.:|||.:.|::.||:
Zfish   138 YFYKRRPIANGIAMAGSPVFLSTLAPLNSWLFDQFGWRGSFLILGGALLNCCVAGSLMRPI---- 198

  Fly   218 PPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGH 282
               .|...|:.||            ..||::|
Zfish   199 ---GPKPQPAIPK------------EDAEIKP--------------------------------- 215

  Fly   283 NLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYR 347
                                                                             
Zfish   216 ----------------------------------------------------------------- 215

  Fly   348 PDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD 412
                                                           ||:          |....
Zfish   216 -----------------------------------------------QEK----------KTVMQ 223

  Fly   413 TFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVG 477
            |....::.:|.....|:::.:.|.....|...|.:::..||::..::|..|::|:|.:...:.:.
Zfish   224 TINGFLDLTLFTHRGFLLYLLGNVIMFFGLFAPLVFLSNYAKSKHISKDKAAFLLSILAFTDMIA 288

  Fly   478 RIILGYISDKPWVNRLLVYNVCLTAC--GVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVI 540
            |..:|.:::..||...:.|....:..  ||...:.||..|:...|.|...||...|   .|:||:
Zfish   289 RPSMGLVANTRWVRPRIQYFFAASVLYNGVCHLLAPLSTDYLGFAIYAVFFGVAFG---WLSSVL 350

  Fly   541 ---LVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMF 601
               |:||:|..:.::|.||:.:.:.....:|||:.|.:.|:.|.|...:...|:::.|:.:.:|
Zfish   351 FETLMDLVGAQRFSSAVGLVTIVECAPVLLGPPLLGRLNDIYDDYKYTYQGCGIVLVIASIFLF 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	66/181 (36%)
		MFS	<426..604	CDD:119392	45/181 (25%)
slc16a1b	NP_956379.1	2A0113	1..442	CDD:273325	131/584 (22%)
		MFS	20..415	CDD:119392	124/576 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578876
Domainoid	1	1.000	142	1.000	Domainoid score	I4621
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm6360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.850