Protein Alignment Mct1 and CG12866

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 162/642 - (25%)
• Similarity: 270/642 - (42%)
• Gaps: 134/642 - (20%)

  Fly    28 PPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISS 92
            |||||:|||::..||:..::.||:.::.|:.........:......:::||:.:|..|:||..|:
  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSA 362

  Fly    93 SFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLII---TIGFGTGLGFGLIYLPAIVSVTQYF 154
            ..:||:|.|.|.|||.:.:|..|:.|.::.::..||.   .:....|:...:|:..:.:.|..||
  Fly   363 VLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYF 427

  Fly   155 EAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPP 219
            |..|.:|.|.:..|.|.|..:|..|..:|:...|||..:....|:::..::....:  :|: ||.
  Fly   428 ERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAY--VEV-APT 489

  Fly   220 QTP----PNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYL-------QLPQRTDTAVSGGA 273
            |..    |.:..|                         ..|:|.       .|.|...||
  Fly   490 QVGMYHLPGSSDT-------------------------SSDEYYGNFYVHDYLRQSAMTA----- 524

  Fly   274 LCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQ---LQLTPLRDA 335
              :|.|:....:|....        :|.....|      |.||....|:..||   .|...:|.|
  Fly   525 --KSRSILSTYEPRPKK--------KGCAKFCP------SCSNCCWRRRKKSQNADEQNLLIRPA 573

  Fly   336 HRERSASGTMYRPDALYQG--------SLHNL--PDYVSSRNDLSRSMSGSGV-----------I 379
            ..||.        |..|.|        |..|:  .:::...:|.:......|:           |
  Fly   574 PLERE--------DLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRI 630

  Fly   380 KRYGSLRQSNNVSQSQEEAKCCGCITCSKETRD--TFAEMMNFSLLKDMVFVIFSVSNFCTSIGF 442
            .|....|:.:|.:|.::.       :| :.:|.  |..::.::.|||...|.|...|.|...:||
  Fly   631 SRVHRERRWSNENQKKQN-------SC-RNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGF 687

  Fly   443 NVPYLY-------VVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCL 500
            |:|::|       .|.||..:.          ..||::|.|.|.|||.::.|   .|.....:|
  Fly   688 NIPFVYSSARTTIPVEYARMIG----------PIIGISNLVMRNILGILAYK---RRSWTLGLC- 738

  Fly   501 TACGVSTAMVP-LCHDF--QSLAFYCCVFGFTI----GAYVGLTSVILVDLLGLDKLTNAFGLLL 558
             .||:....|. |...|  ::|.::..::||:.    ..|..|..:|.|..|||.|||||||:..
  Fly   739 -GCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITS 802

  Fly   559 LFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSE 615
            |..|:.:|||..|.|.:..:|.:|:.||..|||.:.:||.:...:|.|.:.:.|.::
  Fly   803 LAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNRMAQ 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	46/180 (26%)
		MFS	<426..604	CDD:119392	61/191 (32%)
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	44/177 (25%)
		MFS	675..>839	CDD:119392	58/178 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449864
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1250
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900