Protein Alignment Mct1 and CG8468

DIOPT Version :9

• Sequence 1: NP_001284810.1
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 681
• Identity: 218/681 - (32%)
• Similarity: 330/681 - (48%)
• Gaps: 91/681 - (13%)

  Fly     1 MVHGPPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDY 65
            :|...|...|.:.:.|. |::......|||.||.|||:..||:...|.||:.:..|:...:.:..
  Fly    17 LVSKQPENIKEENEGEE-EIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAE 80

  Fly    66 FNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIIT 130
            |...|.|.|:::|::.|....:||..|:..||:|.|.|||.|:|.||.|..:|.||.:|..|.:.
  Fly    81 FGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLI 145

  Fly   131 IGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLI 195
            .|...|:||.::|:||:|.:..|||..|:||||:|:||||.|||||||||:.|:.: |||..:.|
  Fly   146 YGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAI 209

  Fly   196 IGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPL------KVLP 254
            .|.|||:|.:||..|||::    |.|...|.......:|..:.....|.|....|      |.||
  Fly   210 QGIIVLSCALFGLAFRPIQ----PITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLP 270

  Fly   255 KDQY-LQLPQRTDTAVSGGALCRSNSVGHNLKP---------NLNNNSNGAVNG-QGPTL----- 303
            :.:: ..:|........|.:       ..|..|         ||....:|...| :|..|
  Fly   271 EGRFAYSMPNSAHNTYMGAS-------QRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRK 328

  Fly   304 ---VTP---PQAVV--------------KSTSNDDI-----------ARKCHSQLQLTP------ 331
               .||   ||.:.              :...||::           ||: |:.....|
  Fly   329 SQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARR-HTVSGRRPQDIGKR 392

  Fly   332 ----LRDAH--RERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNN 390
                ..:||  :..|:|..|||.|..:.|||..:|.| .|:..|:..||    :.|..:
  Fly   393 SAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQY-QSQTSLAYHMS----VTRLPT------ 446

  Fly   391 VSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAET 455
             .|...|.:..||..|.:..|.|.:.|::.:|||...|:..:.|.|.|.:||.||:.::|..|:.
  Fly   447 -KQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKA 510

  Fly   456 LKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLA 520
            ..:.:..|..::|.|||.||..||:.|.:|..|.|..|.:.|..|||.|::|....:..:..:..
  Fly   511 AGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATICSGIVINTATQW 575

  Fly   521 FYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPA 585
            .:...||..|..:..|.|:|.|:|:||:|||||:|.|:||||:|:..|.||.|.:|.:|.||..|
  Fly   576 TFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAA 640

  Fly   586 FLMAGLMIAISGLVMFAIPPLQRLQVRKSER 616
            |..||.:|.:|..:.:.:..:.|.:.|::|:
  Fly   641 FYFAGGLILLSAFLCYPLTWVSRWEERRNEK 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mct1	NP_001284810.1	MFS	35..>213	CDD:119392	79/177 (45%)
		MFS	<426..604	CDD:119392	66/177 (37%)
CG8468	NP_610940.1	MFS	50..>227	CDD:119392	79/177 (45%)
		MFS	<481..658	CDD:119392	66/176 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446237
Domainoid	1	1.000	64	1.000	Domainoid score	I559
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2778
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352338at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm8420
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
	10	9.900